Catalog No.
RHN58202
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
WIF1, WIF-1, Wnt inhibitory factor 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y5W5
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4A23
Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis., PMID:40173259
Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect., PMID:39424806
Identification and validation of plasma biomarkers for diagnosis of breast cancer in South Asian women., PMID:34997107
Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen deficient osteocytes., PMID:33148174
Evolution of RAS Mutational Status in Liquid Biopsies During First-Line Chemotherapy for Metastatic Colorectal Cancer., PMID:32766143
RORA Overexpression Alleviates Nasal Mucosal Injury and Enhances Red Blood Cell Immune Adhesion Function in a Mouse Model of Allergic Rhinitis via Inactivation of the Wnt/β-Catenin Signaling Pathway., PMID:31340215
Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options., PMID:30770859
Exploring pathways for sustained melanogenesis in facial melasma: an immunofluorescence study., PMID:29846953
RAS mutation analysis in circulating tumor DNA from patients with metastatic colorectal cancer: the AGEO RASANC prospective multicenter study., PMID:29438522
Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists., PMID:29129759
Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection., PMID:27193292
Ornithine Decarboxylase Activity Is Required for Prostatic Budding in the Developing Mouse Prostate., PMID:26426536
Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the Wnt inhibitor WIF-1 in systemic sclerosis and fibrosis., PMID:25185156
Wnt modulators in the aqueous humor are associated with outer retinal damage severity in patients with neovascular age-related macular degeneration., PMID:25034605
Neural stem cells inhibit melanin production by activation of Wnt inhibitors., PMID:24016750
Promoter methylation of WNT inhibitory factor-1 and expression pattern of WNT/β-catenin pathway in human astrocytoma: pathologic and prognostic correlations., PMID:23328978
CpG island methylator phenotype and Helicobacter pylori infection associated with gastric cancer., PMID:23049225
CpG island methylator phenotype in plasma is associated with hepatocellular carcinoma prognosis., PMID:22180715
[Myeloma bone disease and RANKL signaling]., PMID:21814021
Epigenetic markers for early detection of nasopharyngeal carcinoma in a high risk population., PMID:21535891
Aberrant PLAG1 expression in pleomorphic adenomas of the salivary gland: a molecular genetic and immunohistochemical study., PMID:21394649
Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation., PMID:20795789
The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition., PMID:20573255
Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma., PMID:19690140
Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation., PMID:19515997
Target genes of the WNT/beta-catenin pathway in Wilms tumors., PMID:16575872
Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations., PMID:15735684
The extracellular matrix component WIF-1 is expressed during, and can modulate, retinal development., PMID:15555925
WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer., PMID:14517837
A new secreted protein that binds to Wnt proteins and inhibits their activities., PMID:10201374