Catalog No.
RHK70801
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200
Target
Serine-protein kinase PIKFYVE, Phosphatidylinositol 3-phosphate 5-kinase, PIKfyve, 1-phosphatidylinositol 3-phosphate 5-kinase, PIKFYVE, FYVE finger-containing phosphoinositide kinase, Type III PIP kinase, PIPkin-III, KIAA0981, PIP5K3, Phosphatidylinositol 3-phosphate 5-kinase type III
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y2I7
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Z30
Phase II trial of multi-tyrosine kinase inhibitor ESK981 in combination with PD-1 inhibitor nivolumab in patients with metastatic castration-resistant prostate cancer., PMID:39503807
Autophagy Blockage Up-Regulates HLA-Class-I Molecule Expression in Lung Cancer and Enhances Anti-PD-L1 Immunotherapy Efficacy., PMID:39409895
Complete Protection from SARS-CoV-2 Lung Infection in Mice Through Combined Intranasal Delivery of PIKfyve Kinase and TMPRSS2 Protease Inhibitors., PMID:37503261
Ribosomal targeting strategy and nuclear labeling to analyze photoreceptor phosphoinositide signatures., PMID:35427794
Loss of PIKfyve drives the spongiform degeneration in prion diseases., PMID:34291577
Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV., PMID:32221306
PIKfyve sensitivity of hERG channels., PMID:23735862
Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40., PMID:14530284
Selective insulin-induced activation of class I(A) phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes., PMID:11476939
Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells., PMID:9858586