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Anti-KAT8 Antibody (R3Z11)

Catalog #:   RHK54201 Specific References (8) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: IF, IHC, WB
Accession: Q9H7Z6
Overview

Catalog No.

RHK54201

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

MYST-1, hMOF, Histone acetyltransferase KAT8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, KAT8, MYST1, MOF, Lysine acetyltransferase 8

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9H7Z6

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3Z11

Data Image
  • Immunofluorescence
    Confocal Immunofluorescence analysis of Eca 109 cells using MOF/MYST1 mouse mAb (green), showing nuclear localization.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carcinoma (F) tissues, showing nuclear localization using MOF/MYST1 mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using MYST1 mouse mAb against Hela (1), HepG2 (2) and SMMC-7721 (3) cell lysate.
References

Processivity and specificity of histone acetylation by the male-specific lethal complex., PMID:38407474

Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis., PMID:33657400

MOF upregulates the estrogen receptor α signaling pathway by its acetylase activity in hepatocellular carcinoma., PMID:33544437

KLF6 Acetylation Promotes Sublytic C5b-9-Induced Production of MCP-1 and RANTES in Experimental Mesangial Proliferative Glomerulonephritis., PMID:32760202

Estrogen/estrogen receptor promotes the proliferation of endometrial carcinoma cells by enhancing hMOF expression., PMID:31990345

G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression., PMID:26960573

H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFb., PMID:24837678

[Preparation and identification of monoclonal antibody against hMOF]., PMID:22007507

Datasheet

Document Download

Anti-KAT8 Antibody (R3Z11).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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For research use only. Not for human or drug use.

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Anti-KAT8 Antibody (R3Z11) [RHK54201]
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