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Anti-SATB2 Antibody (R3Z09)

Catalog #:   RHK53203 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IHC
Accession: Q9UPW6
Overview

Catalog No.

RHK53203

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

SATB2, DNA-binding protein SATB2, KIAA1034, Special AT-rich sequence-binding protein 2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UPW6

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3Z09

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using SATB2 mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using SATB2 mouse mAb with DAB staining.
References

SATB2 immunohistochemistry in osteosarcoma: Utility in diagnosis and differentiation from histologic mimics., PMID:40485468

Conventional (bone-type) giant cell tumor of the larynx: the first case with proven H3-3A: c.103G >T (p.Gly35Trp) mutation., PMID:39565412

TTF-1 is a highly sensitive but not fully specific marker for pulmonary and thyroidal cancer: a tissue microarray study evaluating more than 17,000 tumors from 152 different tumor entities., PMID:39377914

Special at-rich sequence-binding protein 2 and its role in healing of the experimental mandible bone tissue defect filling with a synthetic bone graft material and electrical stimulation impact., PMID:39360717

An extensive immunohistochemical analysis of 290 ovarian adult granulosa cell tumors with 29 markers., PMID:38904760

SATB2, CKAE1/AE3, and synaptophysin as a sensitive immunohistochemical panel for the detection of lymph node metastases of Merkel cell carcinoma., PMID:38066198

Wnt1 induces osteoblastic changes in a well-established osteolytic skeletal metastatic model derived from breast cancer., PMID:37840014

Immunohistochemical Characterization of a Large Cohort of Triple Negative Breast Cancer., PMID:37306115

Chondroblastoma of foot bones; a clinicopathological study of 29 cases confirming the diagnostic utility of H3K36M and H3G34W antibodies at an uncommon site., PMID:37075609

Inhibition of RANKL Expression in Osteocyte-like Differentiated Tumor Cells in Giant Cell Tumor of Bone After Denosumab Treatment., PMID:36971322

Special AT-rich sequence-binding protein 2 (SATB2) in the differential diagnosis of osteogenic and non-osteogenic bone and soft tissue tumors., PMID:36128863

Aberrant expression of SATB2, CDX2, CDH17 and CK20 in hepatocellular carcinoma: a pathological, clinical and outcome study., PMID:34036629

Optimized Immunostaining of Embryonic and Early Postnatal Mouse Brain Sections., PMID:33732758

Identification of key genes involved in tumor immune cell infiltration and cetuximab resistance in colorectal cancer., PMID:33632198

Identification of retinal ganglion cell types expressing the transcription factor Satb2 in three primate species., PMID:33527361

Intestinal, intestinal-type and intestine-localized metastatic adenocarcinoma. Immunohistochemical approach to the differential diagnosis., PMID:33336735

YJ5 as an immunohistochemical marker of osteogenic lineage., PMID:33187685

Immunohistochemical Characterization of Giant Cell Tumor of Bone Treated With Denosumab: Support for Osteoblastic Differentiation., PMID:32773532

Histomorphometric Analysis of Pre- and Post-Denosumab-Treated Giant Cell Tumor of Bone., PMID:32429739

SRSF1-3, a splicing and somatic hypermutation regulator, controls transcription of IgV genes via chromatin regulators SATB2, UBN1 and histone variant H3.3., PMID:31986311

Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations., PMID:31434953

Cellular localization of PD-L1 expression in mismatch-repair-deficient and proficient colorectal carcinomas., PMID:30166615

Decrease of MiR-31 induced by TNF-α inhibitor activates SATB2/RUNX2 pathway and promotes osteogenic differentiation in ethanol-induced osteonecrosis., PMID:30132874

Histone H3K36M mutation and trimethylation patterns in chondroblastoma., PMID:30098026

EWSR1-SMAD3-rearranged Fibroblastic Tumor: An Emerging Entity in an Increasingly More Complex Group of Fibroblastic/Myofibroblastic Neoplasms., PMID:29957732

SATB2 is a supplementary immunohistochemical marker to CDX2 in the diagnosis of colorectal carcinoma metastasis in an unknown primary., PMID:29924451

Clinicopathological, immunohistochemical, and mutational analyses of pulmonary enteric adenocarcinoma: usefulness of SATB2 and β-catenin immunostaining for differentiation from metastatic colorectal carcinoma., PMID:28438615

Interobserver Reproducibility Among Gynecologic Pathologists in Diagnosing Heterologous Osteosarcomatous Component in Gynecologic Tract Carcinosarcomas., PMID:28221217

The utility of SATB2 immunohistochemical expression in distinguishing between osteosarcomas and their malignant bone tumor mimickers, such as Ewing sarcomas and chondrosarcomas., PMID:27465835

BCOR Overexpression Is a Highly Sensitive Marker in Round Cell Sarcomas With BCOR Genetic Abnormalities., PMID:27428733

The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma., PMID:27258560

Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular analysis of a series., PMID:26338802

SATB2 is a sensitive marker for lower gastrointestinal well-differentiated neuroendocrine tumors., PMID:26261600

Metastatic carcinoma of unknown primary: diagnostic approach using immunohistochemistry., PMID:25844674

Small cell osteosarcoma: clinicopathologic, immunohistochemical, and molecular analysis of 36 cases., PMID:25723116

Satb2-independent acquisition of the cholinergic sudomotor phenotype in rodents., PMID:25239161

Cerium promotes bone marrow stromal cells migration and osteogenic differentiation via Smad1/5/8 signaling pathway., PMID:25197425

Analysis of candidate genes for lineage-specific expression changes in humans and primates., PMID:24911366

[Clinicopathologic characteristics and histogenesis of mucinous tumor of peritoneum]., PMID:24842014

Overexpression of SATB1 is associated with biologic behavior in human renal cell carcinoma., PMID:24835085

The role of SATB2 as a diagnostic marker for tumors of colorectal origin: Results of a pathology-based clinical prospective study., PMID:24713733

The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis., PMID:23175820

Abnormal maturation and differentiation of neocortical neurons in epileptogenic cortical malformation: unique distribution of layer-specific marker cells of focal cortical dysplasia and hemimegalencephaly., PMID:22759905

Sonic hedgehog expression in corticofugal projection neurons directs cortical microcircuit formation., PMID:22445340

Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers., PMID:22412953

Generation of monospecific antibodies based on affinity capture of polyclonal antibodies., PMID:21898641

SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas., PMID:21677534

FIAT is co-expressed with its dimerization target ATF4 in early osteoblasts, but not in osteocytes., PMID:19232401

Epitope mapping of antibodies using bacterial surface display., PMID:19029907

SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression., PMID:14701874

Datasheet

Document Download

Anti-SATB2 Antibody (R3Z09).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-SATB2 Antibody (R3Z09) [RHK53203]
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