Catalog No.
RHJ88602
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
IL-11 R-alpha-locus chemokine, CC chemokine ILC, CTACK, Cutaneous T-cell-attracting chemokine, Skinkine, Small-inducible cytokine A27, CCL27, ESkine, C-C motif chemokine 27, ILC, SCYA27
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y4X3
Applications
ELISA, FCM, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X69
Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324
Harnessing immunotherapeutic molecules and diagnostic biomarkers as human-derived adjuvants for MERS-CoV vaccine development., PMID:40181980
Lipid nanoparticles encapsulating both adjuvant and antigen mRNA improve influenza immune cross-protection in mice., PMID:39724768
Status of B-Lymphocyte Subsets and Their Homing Markers in Patients With Post-Kala-Azar Dermal Leishmaniasis., PMID:38527908
Effect of weekly vitamin D supplementation on the severity of atopic dermatitis and type 2 immunity biomarkers in children: A randomized controlled trial., PMID:38483248
Allergen sensitization stratifies IL-31 production by memory T cells in atopic dermatitis patients., PMID:36993985
Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584., PMID:36993977
Unraveling the surface proteomic profile of multiple myeloma to reveal new immunotherapeutic targets and markers of drug resistance., PMID:36311892
Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo., PMID:35839767
Pharmacokinetics, Safety, Efficacy, and Biomarker Profiles During Nemolizumab Treatment of Atopic Dermatitis in Adolescents., PMID:35088348
Immunoinflammatory Biomarkers in Serum Are Associated with Disease Severity in Atopic Dermatitis., PMID:33730733
Biomarkers in atopic dermatitis-a review on behalf of the International Eczema Council., PMID:33516871
Exploration of biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab: A study protocol., PMID:32957324
Correlation analysis between IL-35, IL-36γ, CCL27 and psoriasis vulgaris., PMID:31682473
HCT-116 colorectal cancer cells secrete chemokines which induce chemoattraction and intracellular calcium mobilization in NK92 cells., PMID:30847498
Cytokines and chemokines expression in serum of patients with neuromyelitis optica., PMID:30718956
Tonsillitis exacerbates renal injury in IgA nephropathy through promoting Th22 cells chemotaxis., PMID:29549623
Chemokine CCL27 is a novel plasma biomarker for identification the nasopharyngeal carcinoma patients from the Epstein-Barr virus capsid antigen-specific IgA seropositive population., PMID:29295705
Dysregulation of Circulating Tfr/Tfh Ratio in Primary biliary cholangitis., PMID:28941291
An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium., PMID:28648867
Altered balance of epidermis-related chemokines in epidermolysis bullosa., PMID:28094098
Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity., PMID:27807435
Differentiation and recruitment of IL-22-producing helper T cells in lgA nephropathy., PMID:27725866
A novel molecular disease classifier for psoriasis and eczema., PMID:27193975
Association of nerve growth factor, chemokine (C-C motif) ligands and immunoglobulin E with pruritus in cutaneous T-cell lymphoma., PMID:22948508
CCR10 and its ligands in regulation of epithelial immunity and diseases., PMID:22684736
Differentiation and recruitment of IL-22-producing helper T cells stimulated by pleural mesothelial cells in tuberculous pleurisy., PMID:22199006
No detectable beneficial systemic immunomodulatory effects of a specific synbiotic mixture in infants with atopic dermatitis., PMID:22092915
Cutaneous lymphoma and chemokine., PMID:21628851
Chemokine profile of synovial fluid from normal, osteoarthritis and rheumatoid arthritis patients: CCL25, CXCL10 and XCL1 recruit human subchondral mesenchymal progenitor cells., PMID:20709179
Expression and regulation in the brain of the chemokine CCL27 gene locus., PMID:20605223
Positive treatment effects of ustekinumab in psoriasis: analysis of lesional and systemic parameters., PMID:20536646
Systemic immunization with CCL27/CTACK modulates immune responses at mucosal sites in mice and macaques., PMID:20188250
I-TAC is a dominant chemokine in controlling skin intragraft inflammation via recruiting CXCR3+ cells into the graft., PMID:19875106
Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo., PMID:19847203
Visualizing CD4 T-cell migration into inflamed skin and its inhibition by CCR4/CCR10 blockades using in vivo imaging model., PMID:19832835
Phenotype of atopic dermatitis subjects with a history of eczema herpeticum., PMID:19541356
Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation., PMID:19536139
Cutting edge: rapid accumulation of epidermal CCL27 in skin-draining lymph nodes following topical application of a contact sensitizer recruits CCR10-expressing T cells., PMID:18453562
CCL27-transgenic mice show enhanced contact hypersensitivity to Th2, but not Th1 stimuli., PMID:18266301
Are age-specific high serum IgE levels associated with worse symptomatology in children with atopic dermatitis?, PMID:18173519
Tumor immune escape by the loss of homeostatic chemokine expression., PMID:18025475
CTACK /CCL27 expression in psoriatic skin and its modification after administration of etanercept., PMID:17916208
TNF family molecule LIGHT regulates chemokine CCL27 expression on mouse embryonic stem cell-derived dendritic cells through NF-kappaB activation., PMID:16978841
CTACK/CCL27 accelerates skin regeneration via accumulation of bone marrow-derived keratinocytes., PMID:16931770
Increased serum thymus and activation-regulated chemokine and cutaneous T cell-attracting chemokine levels in children with atopic dermatitis., PMID:16499646
Circulating clonal CLA(+) and CD4(+) T cells in Sezary syndrome express the skin-homing chemokine receptors CCR4 and CCR10 as well as the lymph node-homing chemokine receptor CCR7., PMID:15727636
Induction of cytokine (interleukin-1alpha and tumor necrosis factor-alpha) and chemokine (CCL20, CCL27, and CXCL8) alarm signals after allergen and irritant exposure., PMID:15679580
CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells., PMID:15356112
Increased CCL27-CCR10 expression in allergic contact dermatitis: implications for local skin memory., PMID:15307136
For research use only. Not for human or drug use.
