Catalog No.
RHJ84802
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:50
Target
CC chemokine IMAC, C-C motif chemokine 26, CCL26, Small-inducible cytokine A26, Macrophage inflammatory protein 4-alpha, Thymic stroma chemokine-1, TSC-1, MIP-4-alpha, Eotaxin-3, SCYA26
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y258
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X62
Inhibition of IL-4Rα reduces CCL26 in bronchial epithelial cells from COPD patients., PMID:40470156
T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting., PMID:40370530
Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324
Leptin augments IL-13-induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma., PMID:39581293
Non-invasive strategy: Developing a topical IL-4Rα-specific nanobody for the treatment of allergic airway diseases., PMID:39108557
Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma., PMID:39097197
Effect of benralizumab on histopathology and inflammatory signatures in a clinical cohort of eosinophilic esophagitis., PMID:38986036
Nicotiana benthamiana-derived dupilumab-scFv reaches deep into the cultured human nasal epithelial cells and inhibits CCL26 expression., PMID:38914666
Expression of inducible nitric oxide synthase, nitrotyrosine, eosinophilic peroxidase, eotaxin-3, and galectin-3 in patients with gastroesophageal reflux disease, eosinophilic esophagitis, and in healthy controls: a semiquantitative image analysis of 3,3'-diaminobenzidine-stained esophageal biopsies., PMID:38679488
Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells., PMID:38565563
Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683
The functional role of CST1 and CCL26 in asthma development., PMID:38270326
Th2 cytokine signaling through IL-4Rα increases eotaxin-3 secretion and tension in human esophageal smooth muscle., PMID:37933466
Exploration of efficacy and mechanism of 0.05% cyclosporine eye drops (II) monotherapy in allergic conjunctivitis-associated dry eye., PMID:37904000
Efficacy of dupilumab in patients with uncontrolled, moderate-to-severe asthma with fungal sensitization., PMID:37752621
Eotaxin-2 and eotaxin-3 in malaria exposure and pregnancy., PMID:36380370
Pediatric Eosinophilic Esophagitis: Searching for Serologic Markers., PMID:36197779
Dipeptidyl Peptidase 4 Inhibitor‒Associated Bullous Pemphigoid Is Characterized by an Altered Expression of Cytokines in the Skin., PMID:35921900
Type-2 Cytokines Promote the Secretion of the Eosinophil-Attractant CCL26 by Intestinal Epithelial Cells in Food-Sensitized Patients., PMID:35799778
The Role of Heparan Sulfate in CCL26-Induced Eosinophil Chemotaxis., PMID:35742962
IL-25 blockade augments antiviral immunity during respiratory virus infection., PMID:35508632
Adult allergic rhinitis sufferers have unique nasal mucosal and peripheral blood immune gene expression profiles: A case-control study., PMID:34637606
Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma., PMID:34518591
A Comprehensive Analysis of Immune Constituents in Blood and Bronchoalveolar Lavage Allows Identification of an Immune Signature of Severe Asthma in Children., PMID:34349761
Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases., PMID:34037993
Immunoinflammatory Biomarkers in Serum Are Associated with Disease Severity in Atopic Dermatitis., PMID:33730733
Biomarkers in atopic dermatitis-a review on behalf of the International Eczema Council., PMID:33516871
Exploration of biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab: A study protocol., PMID:32957324
A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER)., PMID:32909660
CCL26 regulates the proportion of CD4+CD25+FOXP3+ Tregs and the production of inflammatory factors in peripheral blood mononuclear cells following acute ischemic stroke via the STAT5 pathway., PMID:32855707
Increased serum CCL26 level is a potential biomarker for the effectiveness of anti-PD1 antibodies in patients with advanced melanoma., PMID:32658051
Thermal Bioprinting Causes Ample Alterations of Expression of LUCAT1, IL6, CCL26, and NRN1L Genes and Massive Phosphorylation of Critical Oncogenic Drug Resistance Pathways in Breast Cancer Cells., PMID:32154227
IgG4 Related Autoimmune Pancreatitis: An Overview and the Emerging Role of Serum Eotaxin as a Potential Treatment Target., PMID:31542909
Pathogenesis of Atopic Dermatitis: Current Paradigm., PMID:31182684
Comparison of the chemokine profiles in the bronchoalveolar lavage fluid between IgG4-related respiratory disease and sarcoidosis: CC-chemokine ligand 1 might be involved in the pathogenesis of sarcoidosis., PMID:31063909
Serum and blister fluid levels of cytokines and chemokines in pemphigus and bullous pemphigoid., PMID:30844553
Dupilumab in patients with uncontrolled asthma: type 2 biomarkers might be predictors of therapeutic efficacy., PMID:30821528
Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs., PMID:30500834
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis., PMID:30194992
Mesenchymal stem cells up-regulate the invasive potential of prostate cancer cells via the eotaxin-3/CCR3 axis., PMID:30029937
Flavanol-Rich Cocoa Powder Interacts with Lactobacillus rhamnossus LGG to Alter the Antibody Response to Infection with the Parasitic Nematode Ascaris suum., PMID:29023393
Immunohistochemical differentiation of eosinophilic esophageal myositis from eosinophilic esophagitis., PMID:27262491
Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26., PMID:27228567
An Overlook to the Characteristics and Roles Played by Eotaxin Network in the Pathophysiology of Food Allergies: Allergic Asthma and Atopic Dermatitis., PMID:26861136
Comparison of eotaxin-3 biomarker in patients with eosinophilic oesophagitis, proton pump inhibitor-responsive oesophageal eosinophilia and gastro-oesophageal reflux disease., PMID:26011446
Serum biomarkers in patients with relapsing eosinophilic granulomatosis with polyangiitis (Churg-Strauss)., PMID:25812008
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis., PMID:25482871
IL-27 and type 2 immunity in asthmatic patients: association with severity, CXCL9, and signal transducer and activator of transcription signaling., PMID:25312760
Distinctive cytokine, chemokine, and antibody responses in Echinococcus multilocularis-infected patients with cured, stable, or progressive disease., PMID:24509604
Editorial: are all eotaxins created equal?, PMID:23906965
For research use only. Not for human or drug use.
