Catalog No.
RHJ61603
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, WB: 1:500-1:2000
Target
CD209, DC-SIGN1, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, CD209 antigen, CLEC4L, DC-SIGN, C-type lectin domain family 4 member L
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NNX6
Applications
ELISA, FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3W69
The evaluation of a novel multi-epitope vaccine against human papillomavirus and Candida albicans., PMID:40390500
Molecular determinants of sialylated IgG anti-inflammatory activity., PMID:40377989
The characterization of technical design of a virus-like structure (VLS) nanodelivery system as vaccine candidate against SARS-CoV-2 variants., PMID:40045463
Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D., PMID:39791910
Simultaneous Blockade of CD209 and CD209L by Monoclonal Antibody Does Not Provide Sufficient Protection Against Multiple Viral Infections In Vivo., PMID:39783143
Autoantibodies in hospitalised patients with COVID-19., PMID:39734590
Development of a candidate vaccine against severe fever with thrombocytopenia syndrome virus using Gn/Gc glycoprotein via multiple expression vectors delivered by attenuated Salmonella confers effective protection in hDC-SIGN transduced mice., PMID:39547019
Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease., PMID:39541970
Development and characterization of dendritic cell internalization and activation assays contributing to the immunogenicity risk evaluation of biotherapeutics., PMID:39229274
Exosomes multiplex profiling, a promising strategy for early diagnosis of laryngeal cancer., PMID:38902710
Virus-like structures for combination antigen protein mRNA vaccination., PMID:38802667
Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is a cellular receptor for delta inulin adjuvant., PMID:38757764
Sialylated IVIg promotes clinical improvements in a rabbit dry eye model by regulating inflammatory cytokines., PMID:38199260
The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm., PMID:37891014
SARS-CoV-2 suppresses TLR4-induced immunity by dendritic cells via C-type lectin receptor DC-SIGN., PMID:37844099
High infiltration of CD209+ dendritic cells and CD163+ macrophages in the peritumor area of prostate cancer is predictive of late adverse outcomes., PMID:37435060
Localization of macrophages and dendritic cells in human thoracic lymph nodes: An immunohistochemical study using surgically obtained specimens., PMID:37024113
Life stage-specific glycosylation of extracellular vesicles from Schistosoma mansoni schistosomula and adult worms drives differential interaction with C-type lectin receptors DC-SIGN and MGL., PMID:37006612
Distribution of DC Subtypes: CD83+, DC-LAMP+, CD1a+, CD1c+, CD123+, and DC-SIGN+ in the Tumor Microenvironment of Endometrial Cancers-Correlation with Clinicopathologic Features., PMID:36768258
Sialylated IVIg binding to DC-SIGN+ Hofbauer cells induces immune tolerance through the caveolin-1/NF-kB pathway and IL-10 secretion., PMID:36581222
ACE2-Independent Alternative Receptors for SARS-CoV-2., PMID:36423144
Importance of NFκβ, IL-10 serum levels and DC-SIGN polymorphic haplotypes in determining dengue disease severity among eastern Indian patients., PMID:36356794
Fusion Proteins CLD and CLDmut Demonstrate Potent and Broad Neutralizing Activity against HIV-1., PMID:35891347
HCV inhibits M2a, M2b and M2c macrophage polarization via HCV core protein engagement with Toll-like receptor 2., PMID:35837038
HDAC Inhibition with Valproate Improves Direct Cytotoxicity of Monocytes against Mesothelioma Tumor Cells., PMID:35565292
CSF-1-induced DC-SIGN+ macrophages are present in the ovarian endometriosis., PMID:35260161
BSG/CD147 and ACE2 receptors facilitate SARS-CoV-2 infection of human iPS cell-derived kidney podocytes., PMID:34816259
Changes in phenotypic patterns of blood monocytes after kidney transplantation and during acute rejection., PMID:34505523
Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies., PMID:34464958
Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior., PMID:34424958
DC-SIGN binding to mannosylated B-cell receptors in follicular lymphoma down-modulates receptor signaling capacity., PMID:34083646
Expression of the human or porcine C-type lectins DC-SIGN/L-SIGN confers susceptibility to porcine epidemic diarrhea virus entry and infection in otherwise refractory cell lines., PMID:34022357
Circulating extracellular vesicles are endowed with enhanced procoagulant activity in SARS-CoV-2 infection., PMID:33971404
Characterization of the robust humoral immune response to GSK2618960, a humanized anti-IL-7 receptor monoclonal antibody, observed in healthy subjects in a Phase 1 study., PMID:33755713
Toward a humanized mouse model of Pneumocystis pneumonia., PMID:33491669
Proteus mirabilis Targets Atherosclerosis Plaques in Human Coronary Arteries via DC-SIGN (CD209)., PMID:33488579
Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays., PMID:33278960
Immunohistochemical Study of SARS-CoV-2 Viral Entry Factors in the Cornea and Ocular Surface., PMID:32826650
CD209 C-Type Lectins Promote Host Invasion, Dissemination, and Infection of Toxoplasma gondii., PMID:32391004
Antibody combinations for optimized staining of macrophages in human lung tumours., PMID:32299134
Blockade of DC-SIGN+ Tumor-Associated Macrophages Reactivates Antitumor Immunity and Improves Immunotherapy in Muscle-Invasive Bladder Cancer., PMID:32060149
Murine SIGNR1 (CD209b) Contributes to the Clearance of Uropathogenic Escherichia coli During Urinary Tract Infections., PMID:31998663
Transglutaminase 3 Promotes Skin Inflammation in Atopic Dermatitis by Activating Monocyte-Derived Dendritic Cells via DC-SIGN., PMID:31425706
Human DC-SIGN and CD23 do not interact with human IgG., PMID:31292524
HIV-1 subtype C Envelope function becomes less sensitive to N-glycosylation deletion during disease progression., PMID:31208438
Novel trisaccharide based phospholipids as immunomodulators., PMID:31200340
Immune cell populations residing in mesenteric adipose depots and mesenteric lymph nodes of lean dairy cows., PMID:30799109
A high mucosal blocking score is associated with HIV protection., PMID:30703069
Dynamic modulation of DC-SIGN and FcΥR2A receptors expression on platelets in dengue., PMID:30412591
Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses via Basophil Interleukin (IL)-4 and IL-13., PMID:30364177
For research use only. Not for human or drug use.
