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Anti-FOXP1 Antibody (R3W45)

Catalog #:   RHJ56302 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IHC, WB
Accession: Q9H334
Overview

Catalog No.

RHJ56302

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

FOXP1, MFH, Forkhead box protein P1, Mac-1-regulated forkhead

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9H334

Applications

ELISA, FCM, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3W45

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Jurkat cells using FOXP1 mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human breast cancer tissues using FOXP1 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using FOXP1 mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using FOXP1 mouse mAb against HeLa (1), Jurkat (2), MCF-7 (3), T47D (4), and Raw264.7 (5) cell lysate.
References

Expression and regulation of SETBP1 in the song system of male zebra finches (Taeniopygia guttata) during singing., PMID:39580495

Follicular lymphoma comprises germinal center-like and memory-like molecular subtypes with prognostic significance., PMID:39374535

LIM domain only 7: a novel driver of immune evasion through regulatory T cell differentiation and chemotaxis in pancreatic ductal adenocarcinoma., PMID:39143228

The Combination of Anti-CD47 Antibody with CTLA4 Blockade Enhances Anti-Tumor Immunity in Non-Small Cell Lung Cancer via Normalization of Tumor Vasculature and Reprogramming of the Immune Microenvironment., PMID:38398223

Stepwise differentiation of follicular helper T cells reveals distinct developmental and functional states., PMID:38001088

NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer., PMID:37818745

Ki67 proliferation index in follicular lymphoma is associated with favorable outcome in patients treated with R-CHOP., PMID:37226602

A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia., PMID:36016656

Comprehensive Analysis of lncRNA Expression Profile and the Potential Role of ENST00000604491 in Graves' Disease., PMID:35509980

MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination., PMID:34586363

MAb NJ001 inhibits lung adenocarcinoma invasiveness by directly regulating TIMP-3 promoter activity via FOXP1 binding sites., PMID:32744429

The life and death of the germinal center., PMID:31751845

Novel markers in pediatric-type follicular lymphoma., PMID:31686194

MicroRNA miR-34a downregulates FOXP1 during DNA damage response to limit BCR signalling in chronic lymphocytic leukaemia B cells., PMID:30111844

Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis., PMID:30100403

Foxp1 controls mature B cell survival and the development of follicular and B-1 B cells., PMID:29507226

FOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab and chemotherapy., PMID:29122756

Splicing regulators in endothelial cell differentiation., PMID:28661931

Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα., PMID:28555620

[Application of rabbit monoclonal antibody GCET2 in diagnosis of diffuse large B cell lymphoma]., PMID:28056299

Clinicopathological characteristics and genomic profile of primary sinonasal tract diffuse large B cell lymphoma (DLBCL) reveals gain at 1q31 and RGS1 encoding protein; high RGS1 immunohistochemical expression associates with poor overall survival in DLBCL not otherwise specified (NOS)., PMID:27775850

The significance of FOXP1 in diffuse large B-cell lymphoma., PMID:27678023

Neuropilin-1highCD4⁺CD25⁺ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis., PMID:27239104

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures., PMID:27224915

N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells., PMID:27056922

FOXP1 Expression in Normal and Neoplastic Erythroid and Myeloid Cells., PMID:26898077

Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling., PMID:26799990

Accumulation of FoxP3+ T regulatory cells in the tumor microenvironment of human colorectal adenomas., PMID:26724144

FOXP1 functions as an oncogene in promoting cancer stem cell-like characteristics in ovarian cancer cells., PMID:26654944

FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas., PMID:26500140

The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes., PMID:26350416

Low HIP1R mRNA and protein expression are associated with worse survival in diffuse large B-cell lymphoma patients treated with R-CHOP., PMID:26341140

IgG4-positive extranodal marginal zone lymphoma arising in Hashimoto's thyroiditis: clinicopathological and cytogenetic features of a hitherto undescribed condition., PMID:26332259

Primary testicular diffuse large B-cell lymphoma displays distinct clinical and biological features for treatment failure in rituximab era: a report from the International PTL Consortium., PMID:26308769

The forkhead transcription factor FOXP1 represses human plasma cell differentiation., PMID:26289642

Multiparameter analysis of homogeneously R-CHOP-treated diffuse large B cell lymphomas identifies CD5 and FOXP1 as relevant prognostic biomarkers: report of the prospective SAKK 38/07 study., PMID:26071053

MicroRNAs in B-cell lymphomas: how a complex biology gets more complex., PMID:25541152

The expression and correlation between the transcription factor FOXP1 and estrogen receptors in epithelial ovarian cancer., PMID:25500588

Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production., PMID:25278262

miR in CLL: more than mere markers of prognosis?, PMID:24993874

The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells., PMID:24859450

miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1., PMID:24787006

Prognostic significance of immunohistochemistry-based markers and algorithms in immunochemotherapy-treated diffuse large B cell lymphoma patients., PMID:24117687

Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients., PMID:23884370

Human pluripotent stem cell differentiation into authentic striatal projection neurons., PMID:23625190

Inflammation and vascular injury: basic discovery to drug development., PMID:22785436

Abnormal maturation and differentiation of neocortical neurons in epileptogenic cortical malformation: unique distribution of layer-specific marker cells of focal cortical dysplasia and hemimegalencephaly., PMID:22759905

Diffuse large B-cell lymphoma of the orbit: clinicopathologic, immunohistochemical, and prognostic features of 20 cases., PMID:22503694

Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: a report from the International DLBCL Rituximab-CHOP Consortium Program Study., PMID:22437443

Inter- and intra-observational variability in immunohistochemistry: a multicentre analysis of diffuse large B-cell lymphoma staining., PMID:22372580

Datasheet

Document Download

Anti-FOXP1 Antibody (R3W45).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-FOXP1 Antibody (R3W45) [RHJ56302]
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