Catalog No.
RHJ55106
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000
Target
APG5-like, Apoptosis-specific protein, ASP, APG5L, ATG5, Autophagy protein 5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H1Y0
Applications
ELISA, FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3W35
Fangchinoline-mediated autophagy inhibition amplifies antigen presentation and PD-1 blockade efficacy in lung cancer., PMID:40269245
Rituximab-Chidamide combination chemotherapy enhances autophagy to overcome drug resistance in diffuse large B-cell lymphoma., PMID:40258315
Dual roles of CXCR4 (C-X-C motif chemokine receptor 4) in promoting entry of ebolavirus and targeting excessive glycoprotein for reticulophagic degradation to facilitate viral fitness., PMID:40223186
Deciphering the role of TMEM164 in autophagy-mediated ferroptosis and immune modulation in non-small cell lung cancer., PMID:39798196
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy., PMID:39725039
Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation., PMID:39508267
TMEM164 promotes ferroptosis by selectively mediating ATG5-dependent autophagosome formation to inhibit the progression of LUAD., PMID:39392409
Genetic polymorphisms to identify patients with an optimal response to tildrakizumab in psoriasis patients from real-life clinical practice., PMID:39081053
Extracellular NCOA4 is a mediator of septic death by activating the AGER-NFKB pathway., PMID:38916095
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity., PMID:38869076
M6A RNA Methylation-Mediated Dysregulation of AGAP2-AS1 Promotes Trastuzumab Resistance of Breast Cancer., PMID:38744264
Bone marrow mesenchymal stem cells suppress activated CD4+ T cells proliferation through TGF-beta and IL10 dependent of autophagy in pathological hypoxic microenvironment., PMID:38340652
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185., PMID:38084826
Upregulation of ATG9b by propranolol promotes autophagic cell death of hepatic stellate cells to improve liver fibrosis., PMID:37970991
Immunomodulatory mechanisms of an acidic polysaccharide from the fermented burdock residue by Rhizopus nigricans in RAW264.7 cells and cyclophosphamide-induced immunosuppressive mice., PMID:37619680
Autophagy and mitophagy-related extracellular mitochondrial dysfunction of cerebrospinal fluid cells in patients with hemorrhagic moyamoya disease., PMID:37612316
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice., PMID:37477632
Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization., PMID:37239846
Evaluation of the mTORC activity in the presence of Toxoplasma gondii and azathioprine in human monocyte cell line., PMID:36941573
Porcine reproductive and respiratory syndrome virus degrades DDX10 via SQSTM1/p62-dependent selective autophagy to antagonize its antiviral activity., PMID:36779599
Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs., PMID:36587218
High plasma concentrations of acyl-coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP., PMID:36510662
Methamphetamine and HIV-1 Tat proteins synergistically induce microglial autophagy via activation of the Nrf2/NQO1/HO-1 signal pathway., PMID:36162528
Salvianolic acid B inhibits autophagy and activation of hepatic stellate cells induced by TGF-β1 by downregulating the MAPK pathway., PMID:35991894
Branched-chain amino acid transaminase 1 inhibition attenuates childhood asthma in mice by effecting airway remodeling and autophagy., PMID:35961527
Curcumin antagonizes inflammation and autophagy induced by arsenic trioxide through immune protection in duck spleen., PMID:35653021
Vitamin D Attenuates Airway Inflammation in Asthmatic Guinea Pigs Using Mammalian Target of Rapamycin-Mediated Autophagy., PMID:35438528
The biomechanistic aspects of renal cortical injury induced by diesel exhaust particles in rats and the renoprotective contribution of quercetin pretreatment: Histological and biochemical study., PMID:34751495
Bortezomib alleviates antibody-mediated rejection in kidney transplantation by facilitating Atg5 expression., PMID:34734681
Autophagic secretion of HMGB1 from cancer-associated fibroblasts promotes metastatic potential of non-small cell lung cancer cells via NFκB signaling., PMID:34552063
Curcumin Blunts IL-6 Dependent Endothelial-to-Mesenchymal Transition to Alleviate Renal Allograft Fibrosis Through Autophagy Activation., PMID:34122411
Nrg1β Released in Remote Ischemic Preconditioning Improves Myocardial Perfusion and Decreases Ischemia/Reperfusion Injury via ErbB2-Mediated Rescue of Endothelial Nitric Oxide Synthase and Abrogation of Trx2 Autophagy., PMID:34039018
Positively Correlated CD47 Activation and Autophagy in Umbilical Cord Blood-Derived Mesenchymal Stem Cells during Senescence., PMID:33936211
The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore., PMID:33783314
Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism., PMID:33749503
Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes., PMID:33730050
CD36 and LC3B initiated autophagy in B cells regulates the humoral immune response., PMID:33535890
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293
Tofacitinib counteracts IL-6 overexpression induced by deficient autophagy: implications in Sjögren's syndrome., PMID:33216905
The Role of Autophagy-Mediated Dengue Virus Antibody-Dependent Enhancement Infection of THP-1 Cells., PMID:33202415
The Role of Macrophage Migration Inhibitory Factor (MIF) in Asthmatic Airway Remodeling., PMID:33191679
Assessing methods to quantitatively validate TGFβ-dependent autophagy., PMID:33168592
Vitamin D - A host directed autophagy mediated therapy for tuberculosis., PMID:33039674
Role of autophagy in nerve cell apoptosis in mice infected with street rabies virus., PMID:33034763
An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells., PMID:32897127
Mycoplasma pneumoniae lipids license TLR-4 for activation of NLRP3 inflammasome and autophagy to evoke a proinflammatory response., PMID:32894580
lncRNA ZNF649-AS1 Induces Trastuzumab Resistance by Promoting ATG5 Expression and Autophagy., PMID:32735773
Doxycycline decreases amyloidogenic light chain-induced autophagy in isolated primary cardiac myocytes., PMID:32682005
Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice., PMID:32677505
Alpha-neoendorphin can reduce UVB-induced skin photoaging by activating cellular autophagy., PMID:32526201
For research use only. Not for human or drug use.
