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Anti-CAMK4 Antibody (R3U38)

Catalog #:   RHH29601 Specific References (47) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF, IHC, WB
Accession: Q16566
Overview

Catalog No.

RHH29601

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

CAMK, CaMK IV, CaM kinase-GR, CAMKIV, Calcium/calmodulin-dependent protein kinase type IV, CAMK-GR, CAMK4

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q16566

Applications

ELISA, FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3U38

Data Image
  • Immunofluorescence
    Immunofluorescence analysis of HepG2 cells using CAMK4 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using CAMK4 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CAMK4 mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using CAMK4 mouse mAb against Jurkat (1), SK-N-SH (2), Raji (3), and HeLa (4) cell lysate.
References

Calcium calmodulin kinase IV deficiency in podocytes prevents the development of lupus nephritis., PMID:39793862

The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression., PMID:38467629

CaMK4 controls follicular helper T cell expansion and function during normal and autoimmune T-dependent B cell responses., PMID:38287012

Fasudil compensates podocyte injury via CaMK4/Rho GTPases signal and actin cytoskeleton-dependent activation of YAP in MRL/lpr mice., PMID:37094544

Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: dual effect on Th17 cell activation and osteoclastogenesis., PMID:35781320

Anti-phospholipase A2 receptor antibodies directly induced podocyte damage in vitro., PMID:35333675

Aberrantly glycosylated IgG elicits pathogenic signaling in podocytes and signifies lupus nephritis., PMID:33784256

N-glycosylated IgG in patients with kidney transplants increases calcium/calmodulin kinase IV in podocytes and causes injury., PMID:32531122

Promotion of Calcium/Calmodulin-Dependent Protein Kinase 4 by GLUT1-Dependent Glycolysis in Systemic Lupus Erythematosus., PMID:30462889

Activation of CaMKIV by soluble amyloid-β1-42 impedes trafficking of axonal vesicles and impairs activity-dependent synaptogenesis., PMID:28698220

Hepatitis B virus X protein stimulates high mobility group box 1 secretion and enhances hepatocellular carcinoma metastasis., PMID:28216372

Lupus Nephritis IgG Induction of Calcium/Calmodulin-Dependent Protein Kinase IV Expression in Podocytes and Alteration of Their Function., PMID:26636664

In vivo immunotoxicity of perfluorooctane sulfonate in BALB/c mice: Identification of T-cell receptor and calcium-mediated signaling pathway disruption through gene expression profiling of the spleen., PMID:26300304

IB4-binding sensory neurons in the adult rat express a novel 3' UTR-extended isoform of CaMK4 that is associated with its localization to axons., PMID:23817991

New therapeutics in systemic lupus erythematosus., PMID:23492737

Potential characteristics of stem cells from human exfoliated deciduous teeth compared with bone marrow-derived mesenchymal stem cells for mineralized tissue-forming cell biology., PMID:22099898

Lack of action of exogenously administered T3 on the fetal rat brain despite expression of the monocarboxylate transporter 8., PMID:21303950

The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo., PMID:19776387

Temporal assessment of histone H3 phospho-acetylation and casein kinase 2 activation in dentate gyrus from ischemic rats., PMID:19765564

The Balpha and Bdelta regulatory subunits of PP2A are necessary for assembly of the CaMKIV.PP2A signaling complex., PMID:19538941

X-box-binding protein 1 activates lytic Epstein-Barr virus gene expression in combination with protein kinase D., PMID:17494074

HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage., PMID:17038545

Identification of a biphasic signaling pathway involved in ischemic resistance of the hippocampal dentate gyrus., PMID:16996500

Calmodulin-dependent protein kinases phosphorylate gp130 at the serine-based dileucine internalization motif., PMID:16036214

Regulation of the human atrial myosin light chain 1 promoter by Ca2+-calmodulin-dependent signaling pathways., PMID:15791000

Generation of a polyclonal antibody that simultaneously detects multiple Ser/Thr protein kinases., PMID:15236906

Skeletal muscle adaptation in response to voluntary running in Ca2+/calmodulin-dependent protein kinase IV-deficient mice., PMID:15229108

A new approach for the detection of multiple protein kinases using monoclonal antibodies directed to the highly conserved region of protein kinases., PMID:14596830

Involvement of calcium/calmodulin-dependent protein kinase II in the induction of mPer1., PMID:12692905

Activation of Ca2+/calmodulin-dependent protein kinase I in cultured rat hippocampal neurons., PMID:12153482

Amyloid precursor protein family-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway., PMID:11877414

Immunohistochemical localization of Ca(2+)/calmodulin-dependent protein kinase kinase beta in the rat central nervous system., PMID:11223463

A possible role for Ca(2+)/calmodulin-dependent protein kinase IV during pancreatic acinar stimulus-secretion coupling., PMID:10838169

Age-related decline in activation of calcium/calmodulin-dependent phosphatase calcineurin and kinase CaMK-IV in rat T cells., PMID:10656183

Distinct immunohistochemical localization of two isoforms of Ca2+/calmodulin-dependent protein kinase kinases in the adult rat brain., PMID:10651863

High-affinity cholecystokinin type A receptor/cytosolic phospholipase A2 pathways mediate Ca2+ oscillations via a positive feedback regulation by calmodulin kinase in pancreatic acini., PMID:10535305

Immunological evidence that the beta isoform of Ca2+/calmodulin-dependent protein kinase IV is a cerebellar granule cell-specific product of the CaM kinase IV gene., PMID:10383642

Differential effects of a calcineurin inhibitor on glutamate-induced phosphorylation of Ca2+/calmodulin-dependent protein kinases in cultured rat hippocampal neurons., PMID:10085155

Immunohistochemical localization of Ca2+/Calmodulin-dependent protein kinase IV in outer hair cells., PMID:9857208

Involvement of calmodulin-dependent protein kinases-I and -IV in long-term potentiation., PMID:9163554

Ca2+/calmodulin-dependent protein kinase type IV in dorsal root ganglion: colocalization with peptides, axonal transport and effect of axotomy., PMID:8793097

Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma., PMID:8615909

Activation of Ca2+/calmodulin-dependent protein kinase (CaM-kinase) IV by CaM-kinase kinase in Jurkat T lymphocytes., PMID:8530476

The cDNA sequence and characterization of the Ca2+/calmodulin-dependent protein kinase-Gr from human brain and thymus., PMID:8194751

cDNA cloning and expression of human calmodulin-dependent protein kinase IV., PMID:8089075

A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1., PMID:8107230

Nuclear and axonal localization of Ca2+/calmodulin-dependent protein kinase type Gr in rat cerebellar cortex., PMID:2011593

Datasheet

Document Download

Anti-CAMK4 Antibody (R3U38).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-CAMK4 Antibody (R3U38) [RHH29601]
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