Catalog No.
RHH15903
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100
Target
IKBB, IkB-beta, TRIP9, TRIP-9, IkappaBbeta, I-kappa-B-beta, IkB-B, NFKBIB, NF-kappa-B inhibitor beta, TR-interacting protein 9, NF-kappa-BIB, Thyroid receptor-interacting protein 9
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15653
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T88
IL-1α released from oral epithelial cells upon candidalysin exposure initiates an early innate epithelial response., PMID:33038250
A Novel Mechanism for NF-κB-activation via IκB-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation., PMID:32912968
Functional importance of stripping in NFκB signaling revealed by a stripping-impaired IκBα mutant., PMID:28167786
Detection of huntingtin exon 1 phosphorylation by Phos-Tag SDS-PAGE: Predominant phosphorylation on threonine 3 and regulation by IKKβ., PMID:26106822
Compressive mechanical stress may activate IKK-NF-κB through proinflammatory cytokines in MC3T3-E1 cells., PMID:25967035
Stem cell factor induces AP-1-dependent mast cell IL-6 production via MAPK kinase 3 activity., PMID:24453276
A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation., PMID:22856597
Inactivation of I kappaB-kinase-beta dependent genes in airway epithelium reduces tobacco smoke induced acute airway inflammation., PMID:20494824
The rGel/BLyS fusion toxin inhibits diffuse large B-cell lymphoma growth in vitro and in vivo., PMID:20454508
Lipopolysaccharide induces calcitonin gene-related peptide in the RAW264.7 macrophage cell line., PMID:20141542
Functional antagonism by GM-CSF on TNF-alpha-induced CD83 expression in human neutrophils., PMID:18755511
The role of IkappaBalpha in TNF-alpha-induced apoptosis in hepatic stellate cell line HSC-T6., PMID:17828497
High-content classification of nucleocytoplasmic import or export inhibitors., PMID:17507639
5-Androstenediol promotes survival of gamma-irradiated human hematopoietic progenitors through induction of nuclear factor-kappaB activation and granulocyte colony-stimulating factor expression., PMID:17473057
Upregulated expression of kappa light chain by Epstein-Barr virus encoded latent membrane protein 1 in nasopharyngeal carcinoma cells via NF-kappaB and AP-1 pathways., PMID:16979873
Lipopolysaccharide induces CXCL2/macrophage inflammatory protein-2 gene expression in enterocytes via NF-kappaB activation: independence from endogenous TNF-alpha and platelet-activating factor., PMID:16771850
The cellular distribution of the Wld s chimeric protein and its constituent proteins in the CNS., PMID:16154290
IL-17 reduces TNF-induced Rantes and VCAM-1 expression., PMID:15975820
BCG promotes cord blood monocyte-derived dendritic cell maturation with nuclear Rel-B up-regulation and cytosolic I kappa B alpha and beta degradation., PMID:12672905
Thrombin induces nitric-oxide synthase via Galpha12/13-coupled protein kinase C-dependent I-kappaBalpha phosphorylation and JNK-mediated I-kappaBalpha degradation., PMID:12606553
Differential usage of IkappaBalpha and IkappaBbeta in regulation of apoptosis versus gene expression., PMID:12535663
16K prolactin induces NF-kappaB activation in pulmonary fibroblasts., PMID:12475392
Potential role of nuclear factor kappaB and reactive oxygen species in cAMP and cytokine regulation of surfactant protein-A gene expression in lung type II cells., PMID:12040027
Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly., PMID:11943206
Multi-parameter analysis of the kinetics of NF-kappaB signalling and transcription in single living cells., PMID:11884514
TNF-alpha mediates SDF-1 alpha-induced NF-kappa B activation and cytotoxic effects in primary astrocytes., PMID:11489936
Effect of a synthetic lipid immunomodulator on the regulation of the transcription factor NF-kappaB., PMID:11105779
Mechanisms of persistent NF-kappa B activity in the bronchi of an animal model of asthma., PMID:11067942
IkappaBbeta-related proteins in normal and transformed colonic epithelial cells., PMID:11020244
Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice., PMID:10702415
The signal transduction pathway of CD23 (Fc epsilon RIIb) targets I kappa B kinase., PMID:10490984
Constitutive nuclear translocation of NF-kappa B in B cells in the absence of I kappa B degradation., PMID:10384125
Characterization of a neuronal kappaB-binding factor distinct from NF-kappaB., PMID:10216229
Human mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase cascades., PMID:9841871
Nuclear factor NF-kappa B in myocardium: developmental expression of subunits and activation by interleukin-1 beta in cardiac myocytes in vitro., PMID:9798528
Herpes simplex type 1 induction of persistent NF-kappa B nuclear translocation increases the efficiency of virus replication., PMID:9705914
CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel., PMID:9570540
Expression of constitutively active IkappaB beta in T cells of transgenic mice: persistent NF-kappaB activity is required for T-cell immune responses., PMID:9418895
Proteasome regulation of Fas ligand cytotoxicity., PMID:9341769
Persistent activation of NF-kappa B/Rel by human T-cell leukemia virus type 1 tax involves degradation of I kappa B beta., PMID:8627746
Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation., PMID:8497253
The C terminus of the NF-kappa B p50 precursor and an I kappa B isoform contain transcription activation domains., PMID:1598203
For research use only. Not for human or drug use.
