Catalog No.
RHG87003
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
DXS423E, SB1.8, KIAA0178, Structural maintenance of chromosomes protein 1A, SMC-1A, Sb1.8, SMC1, SMC1A, SMC protein 1A, SMC1L1, SMC-1-alpha
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14683
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T29
Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development., PMID:39627609
IRX3/5 regulate mitotic chromatid segregation and limb bud shape., PMID:32907847
Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators., PMID:25875106
SMC1-mediated intra-S-phase arrest facilitates bocavirus DNA replication., PMID:23365434
In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex., PMID:22628566
Telomere shortening alters the kinetics of the DNA damage response after ionizing radiation in human cells., PMID:21930799
Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISA., PMID:21388270
The foci of DNA double strand break-recognition proteins localize with gammaH2AX after heat treatment., PMID:20173316
Meiotic chromosome pairing and bouquet formation during Eimeria tenella sporulation., PMID:19837073
PTIP regulates 53BP1 and SMC1 at the DNA damage sites., PMID:19414588
Rapid flow cytometry-based structural maintenance of chromosomes 1 (SMC1) phosphorylation assay for identification of ataxia-telangiectasia homozygotes and heterozygotes., PMID:19147735
No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells., PMID:19071232
Cohesin subunit SMC1 associates with mitotic microtubules at the spindle pole., PMID:18832153
Cohesin protein SMC1 is a centrosomal protein., PMID:18515072
Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment., PMID:18468964
The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR., PMID:18375193
RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins., PMID:16043481
Characterization of Arabidopsis thaliana SMC1 and SMC3: evidence that AtSMC3 may function beyond chromosome cohesion., PMID:15972315
Hinderin, a five-domains protein including coiled-coil motifs that binds to SMC3., PMID:15656913
SMC1 involvement in fragile site expression., PMID:15640246
Cohesin component dynamics during meiotic prophase I in mammalian oocytes., PMID:15125634
ATP hydrolysis is required for cohesin's association with chromosomes., PMID:14614819
Localization of human SMC1 protein at kinetochores., PMID:12199140
STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis., PMID:12034751
A potential role for human cohesin in mitotic spindle aster assembly., PMID:11590136
Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I., PMID:11483963
Association of mammalian SMC1 and SMC3 proteins with meiotic chromosomes and synaptonemal complexes., PMID:10652260
Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1., PMID:10072753
A 71-kDa protein from Halobacterium salinarium belongs to a ubiquitous P-loop ATPase superfamily with head-rod-tail structure., PMID:9396829
SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family., PMID:8276886
Rabbit ductus arteriosus during development: anatomical structure and smooth muscle cell composition., PMID:8417632
For research use only. Not for human or drug use.
