Catalog No.
RHG86803
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
Tyrosine-protein kinase MELK, Maternal embryonic leucine zipper kinase, Protein kinase Eg3, hMELK, MELK, Protein kinase PK38, hPK38, pEg3 kinase, KIAA0175
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14680
Applications
ELISA, FCM, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T28
Incidence, risk factors, management strategies, and outcomes of antibody-mediated rejection in pediatric kidney transplant recipients-a multicenter analysis of the Cooperative European Paediatric Renal Transplant Initiative (CERTAIN)., PMID:39283519
Progression-free survival after front line, second line and third line in patients with follicular lymphoma treated in clinical practice., PMID:38709114
Targeting MELK improves PD-1 blockade efficiency in cervical cancer via enhancing antitumor immunity., PMID:38596298
Mobile SARS‑CoV‑2 screening facilities for rapid deployment and university-based diagnostic laboratory., PMID:36751470
Comparison of two antibody screening systems for SARS-CoV-2 antibody detection in recovered and vaccinated subjects - test performance and possible indicators for immunity., PMID:36279696
Children and Adolescents' Behavioral Patterns in Response to Escalating COVID-19 Restriction Reveal Sex and Age Differences., PMID:34972613
Urinary proteomics to diagnose chronic active antibody-mediated rejection in pediatric kidney transplantation - a pilot study., PMID:30357927
Correction to: MicroRNA-214-3p inhibits proliferation and cell cycle progression by targeting MELK in hepatocellular carcinoma and correlates cancer prognosis., PMID:29652412
MicroRNA-214-3p inhibits proliferation and cell cycle progression by targeting MELK in hepatocellular carcinoma and correlates cancer prognosis., PMID:29151817
Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference., PMID:28319600
OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases., PMID:27082996
Local convection-enhanced delivery of an anti-CD40 agonistic monoclonal antibody induces antitumor effects in mouse glioma models., PMID:26917236
Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia., PMID:25365263
Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo., PMID:20861186
Successful treatment of chronic antibody-mediated rejection with IVIG and rituximab in pediatric renal transplant recipients., PMID:19005402
A three-symbol code for organized proteomes based on cyclical imaging of protein locations., PMID:17326231
Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling., PMID:16316342
Lesions of T-cell-mediated kidney allograft rejection in mice do not require perforin or granzymes A and B., PMID:15084164
Association of elevated blood levels of pentachlorophenol (PCP) with cellular and humoral immunodeficiencies., PMID:11256860
Reduction of viral load and immune complex load on CD4+ lymphocytes as a consequence of highly active antiretroviral treatment (HAART) in HIV-infected hemophilia patients., PMID:10482364
Production and characterization of an antibody specific for a novel protein serine/threonine kinase, MPK38, highly expressed in hematopoietic cells., PMID:10394617
Microchimerism in sensitized renal patients., PMID:10360597
CD4 depletion in HIV-infected haemophilia patients is associated with rapid clearance of immune complex-coated CD4+ lymphocytes., PMID:10193421
Association of viral load in plasma samples of HIV-infected hemophilia patients with autoantibodies and gp120-containing immune complexes on CD4+ lymphocytes., PMID:9557961
Diagnostic and prognostic significance of anticardiolipin antibodies in patients with recurrent spontaneous abortions., PMID:7546239
Immunogenetic and serological investigations in nonpregnant and in pregnant women with a history of recurrent spontaneous abortions. German RSA/IVIG Study Group., PMID:7884745
[The presence of antibodies against glycoprotein I (gI) of the virus of Aujeszky's disease in colostrum and milk of sows]., PMID:1851579
[Correlation of inguinal hernia and agglutinating sperm antibodies]., PMID:2368519
For research use only. Not for human or drug use.
