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Anti-NEUROD1 Antibody (R3S79)

Catalog #:   RHG58701 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: FCM, IHC, WB
Accession: Q13562
Overview

Catalog No.

RHG58701

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

NEUROD, Neurogenic differentiation factor 1, Class A basic helix-loop-helix protein 3, bHLHa3, NeuroD1, NEUROD1, BHLHA3, NeuroD

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13562

Applications

FCM, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3S79

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using Neurod mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human brain tissues using Neurod mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using Neurod mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using Neurod mouse mAb against WERI-Rb-1 cell lysate.
References

Prognostic Significance of Immunohistochemical Surrogate Molecular Sub-Typing of Small Cell Lung Carcinoma., PMID:40536008

Transient islet-antigen 2 positivity at diagnosis of diabetes during COVID-19 infection in an adolescent with a NEUROD1 variant: a case report., PMID:40474235

Molecular subtyping dictates therapeutic response to anti-PD-L1 immunotherapy in ES-SCLC., PMID:40402312

The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer., PMID:39941061

Dual onsets of small cell lung cancer with contrasting neuroendocrine features and immune microenvironments: A case report., PMID:39919549

Beta cell-specific PAK1 enrichment ameliorates diet-induced glucose intolerance in mice by promoting insulin biogenesis and minimising beta cell apoptosis., PMID:39404845

A novel nonsense mutation c.747C>G in the NEUROD1 gene detected within a Chinese family affected by maturity-onset diabetes of the young type 6., PMID:39264012

A Newly Developed Anti-L1CAM Monoclonal Antibody Targets Small Cell Lung Carcinoma Cells., PMID:39201435

Clinical and Laboratory Characteristics of MODY Cases, Genetic Mutation Spectrum and Phenotype-genotype Relationship., PMID:38665000

Reprogramming of astrocytes to neuronal-like cells in spinal cord injury: a systematic review., PMID:38448665

Screening of Mutations in Maturity-onset Diabetes of the Young-related Genes and RFX6 in Children with Autoantibody-negative Type 1 Diabetes Mellitus., PMID:38054414

Pathologic diagnosis of lung cancer - recent developments., PMID:37975321

Identification of Lineage-specific Transcriptional Factor-defined Molecular Subtypes in Small Cell Bladder Cancer., PMID:37380560

CRISPR/Cas9-Mediated Knockout of tnfaip1 in Zebrafish Plays a Role in Early Development., PMID:37239365

Whole-Section Landscape Analysis of Molecular Subtypes in Curatively Resected Small Cell Lung Cancer: Clinicopathologic Features and Prognostic Significance., PMID:37054974

Identification of inflamed-phenotype of small cell lung cancer leading to the efficacy of anti-PD-L1 antibody and chemotherapy., PMID:37037178

NeuroD1 localizes to the presumptive ganglia and gut of the sea urchin larvae., PMID:36468156

Stress Induced Hyperglycemia in Early Childhood as a Clue for the Diagnosis of NEUROD1-MODY., PMID:36047484

Immune Checkpoint Blockade Outcome in Small-Cell Lung Cancer and Its Relationship With Retinoblastoma Mutation Status and Function., PMID:36044718

Pancreatic-Like Cells Derived From Mouse Embryonic Stem Cells Are Regulated by Pdx1 Involving the Notch Pathway., PMID:35695761

Identification of Variants Responsible for Monogenic Forms of Diabetes in Brazil., PMID:35592779

Differentiation of PC12 cell line into neuron by Valproic acid encapsulated in the stabilized core-shell liposome-chitosan Nano carriers., PMID:35537586

Molecular subtypes of small cell lung cancer transformed from adenocarcinoma after EGFR tyrosine kinase inhibitor treatment., PMID:35004251

Differential Morphological Diagnosis of Various Forms of Congenital Hyperinsulinism in Children., PMID:34497584

Targeting netrin-3 in small cell lung cancer and neuroblastoma., PMID:33719214

SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures., PMID:33086069

Clinical and laboratory clues of maturity-onset diabetes of the young and determination of association with molecular diagnosis., PMID:32710514

Morphological and immunophenotypic characterization of perivascular interstitial cells in human glioma: Telocytes, pericytes, and mixed immunophenotypes., PMID:32064038

In vivo ectopic Ngn1 and Neurod1 convert neonatal cochlear glial cells into spiral ganglion neurons., PMID:32027432

Intestinal Neurod1 expression impairs paneth cell differentiation and promotes enteroendocrine lineage specification., PMID:31862906

Herpes Simplex Virus Type-1 Infection Impairs Adult Hippocampal Neurogenesis via Amyloid-β Protein Accumulation., PMID:31381841

Analysis of pituitary adenoma expression patterns suggests a potential role for the NeuroD1 transcription factor in neuroendocrine tumor-targeting therapies., PMID:30719226

Multihormonal pituitary adenoma concomitant with Pit-1 and Tpit lineage cells causing acromegaly associated with subclinical Cushing's disease: a case report., PMID:28865461

Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry., PMID:27913849

In vitro reprogramming of rat bmMSCs into pancreatic endocrine-like cells., PMID:27699654

Nur77 gene expression levels were involved in different ACTH-secretion autonomy between Cushing's disease and subclinical Cushing's disease., PMID:27025408

Micropatterning Extracellular Matrix Proteins on Electrospun Fibrous Substrate Promote Human Mesenchymal Stem Cell Differentiation Toward Neurogenic Lineage., PMID:26654444

Hypoxic preconditioning differentially affects GABAergic and glutamatergic neuronal cells in the injured cerebellum of the neonatal rat., PMID:25032984

Differentiation of iPSCs into insulin-producing cells via adenoviral transfection of PDX-1, NeuroD1 and MafA., PMID:24794627

A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice., PMID:23804093

The transcription factor Myt3 acts as a pro-survival factor in β-cells., PMID:23236509

Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene., PMID:23142158

MiR-34a represses Numbl in murine neural progenitor cells and antagonizes neuronal differentiation., PMID:22701667

Long-term survival and differentiation of retinal neurons derived from human embryonic stem cell lines in un-immunosuppressed mouse retina., PMID:22539871

Regeneration and DNA demethylation do not trigger PDX-1 expression in rat hepatocytes., PMID:21537485

Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells., PMID:21197711

Exposure to extremely low-frequency (50 Hz) electromagnetic fields enhances adult hippocampal neurogenesis in C57BL/6 mice., PMID:20816824

Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea., PMID:20661473

Retinoic acid directs neuronal differentiation of human pluripotent stem cell lines in a non-cell-autonomous manner., PMID:20427117

Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cells., PMID:19785038

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-NEUROD1 Antibody (R3S79) [RHG58701]
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