Catalog No.
RHG54402
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, WB: 1:500-1:2000
Target
Frizzled-5, FzE5, C2orf31, hFz5, FZD5, Fz-5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13467
Applications
ELISA, FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3S52
Cancer-associated fibroblasts promote growth and dissemination of esophageal squamous cell carcinoma cells by secreting WNT family member 5A., PMID:39954174
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification., PMID:38358799
Ehrlichia Wnt SLiM ligand mimic deactivates the Hippo pathway to engage the anti-apoptotic Yap-GLUT1-BCL-xL axis., PMID:37530530
Ehrlichia Wnt short linear motif ligand mimetic deactivates the Hippo pathway to engage the anti-apoptotic Yap-GLUT1-BCL-xL axis., PMID:36945589
Robust Colonic Epithelial Regeneration and Amelioration of Colitis via FZD-Specific Activation of Wnt Signaling., PMID:35569814
WNT5A Interacts With FZD5 and LRP5 to Regulate Proliferation and Self-Renewal of Endometrial Mesenchymal Stem-Like Cells., PMID:35295855
The fluorescent biosensor for detecting N6 methyladenine FzD5 mRNA and MazF activity., PMID:34794576
IgD promotes pannus formation by activating Wnt5A-Fzd5-CTHRC1-NF-κB signaling pathway in FLS of CIA rats and the regulation of IgD-Fc-Ig fusion protein., PMID:34688134
FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts., PMID:33754039
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo., PMID:32818433
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling., PMID:32762848
A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties., PMID:30183492
Molecular genetics and targeted therapy of WNT-related human diseases (Review)., PMID:28731148
Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors., PMID:27869803
CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling., PMID:27191743
Wnt5a Induces Collagen Production by Human Periodontal Ligament Cells Through TGFβ1-Mediated Upregulation of Periostin Expression., PMID:25655430
WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins., PMID:21070854
A nonautonomous role for retinal frizzled-5 in regulating hyaloid vitreous vasculature development., PMID:18791178
Sustained Wnt protein expression in chondral constructs from mesenchymal stem cells., PMID:15389636
Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas., PMID:12242657
Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled., PMID:11520064
Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation., PMID:11315916
Interaction of Frizzled 7 and Dishevelled in Xenopus., PMID:10906785
For research use only. Not for human or drug use.
