Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Antibody / Recombinant Antibody

Anti-TRAF1 Antibody (R3S05)

Catalog #:   RHG39301 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: Q13077
Overview

Catalog No.

RHG39301

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:250

Target

Epstein-Barr virus-induced protein 6, EBI6, TNF receptor-associated factor 1, TRAF1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13077

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3S05

Data Image
  • Immunohistochemical
    IHC-P analysis of tonsil tissue by TRAF1 antibody (RHG39301). IHC-P was performed using sections of the formalin-fixed paraffin-embedded tonsil tissue;Result: Germinal center cells and non-germinal center cells are positively stained at the cytoplasm and cell membrane.
References

Selective disruption of Traf1/cIAP2 interaction attenuates inflammatory responses and rheumatoid arthritis., PMID:39913998

TRAF1 Deficiency in Macrophages Drives Exacerbated Joint Inflammation in Rheumatoid Arthritis., PMID:39062579

Differential response of IgM and IgG memory B cell populations to CD40L: insights of T cell - memory B cell interactions., PMID:39050849

Machine learning-based prediction of rheumatoid arthritis with development of ACPA autoantibodies in the presence of non-HLA genes polymorphisms., PMID:38517871

Gene expression analysis revealed downregulation of complement receptor 1 in clonal B cells in cold agglutinin disease., PMID:38133636

TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice., PMID:32235829

TRAF1 suppresses antifungal immunity through CXCL1-mediated neutrophil recruitment during Candida albicans intradermal infection., PMID:32093731

Genetic implications in the pathogenesis of rheumatoid arthritis; an updated review., PMID:30904715

CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs., PMID:30524423

Increased serum levels of tumor necrosis factor receptor-associated factor 1 (TRAF1) correlate with disease activity and autoantibodies in rheumatoid arthritis., PMID:27592369

Association of the polymorphisms of TRAF1 (rs10818488) and TNFAIP3 (rs2230926) with rheumatoid arthritis and systemic lupus erythematosus and their relationship to disease activity among Egyptian patients., PMID:27536202

Association of TRAF1-C5 with risk of uveitis in juvenile idiopathic arthritis., PMID:27369649

A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study., PMID:27092776

Fitting Proportional Odds Model to Case-Control data with Incorporating Hardy-Weinberg Equilibrium., PMID:26607176

Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors., PMID:26446946

TRAF1/C5 but not PTPRC variants are potential predictors of rheumatoid arthritis response to anti-tumor necrosis factor therapy., PMID:25834819

A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis., PMID:25566937

A phase I monotherapy study of RG7212, a first-in-class monoclonal antibody targeting TWEAK signaling in patients with advanced cancers., PMID:25388164

A single nucleotide polymorphism of TRAF1 predicts the clinical response to anti-TNF treatment in Japanese patients with rheumatoid arthritis., PMID:24321457

Lack of association of variants previously associated with anti-TNF medication response in rheumatoid arthritis patients: results from a homogeneous Greek population., PMID:24040234

RIP1 expression is necessary for CD30-mediated cell death induction in anaplastic large-cell lymphoma cells., PMID:23545938

Susceptibility to childhood-onset rheumatoid arthritis: investigation of a weighted genetic risk score that integrates cumulative effects of variants at five genetic loci., PMID:23450725

Tumor necrosis factor receptor-associated factor 1 influences KRN/I-Ag7 mouse arthritis autoantibody production., PMID:23354839

Genetics of rheumatoid arthritis - a comprehensive review., PMID:23288628

PAR2-induced inflammatory responses in human kidney tubular epithelial cells., PMID:23283995

TRAF1 gene polymorphism correlates with the titre of Gp210 antibody in patients with primary biliary cirrhosis., PMID:23125866

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments., PMID:22670058

Delineation of apoptotic genes for synergistic apoptosis of lexatumumab and anthracyclines in human renal cell carcinoma cells by polymerase chain reaction array., PMID:22205156

Influence of TRAF1/C5 and STAT4 genes polymorphisms on susceptibility and severity of rheumatoid arthritis in Egyptian population., PMID:22196377

Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection., PMID:22184633

TGF beta1 polymorphisms are candidate predictors of the clinical response to rituximab in rheumatoid arthritis., PMID:22129793

T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy., PMID:22017440

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans., PMID:21804190

An overview on the genetic of rheumatoid arthritis: a never-ending story., PMID:21545847

Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population., PMID:21492465

CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection., PMID:21076066

[cFLIP diminishes CD95-induced apoptosis of CD30-stimulated cutaneous anaplastic large T cell lymphoma (cALCL) cells]., PMID:20812013

Qualitative and quantitative differences in the intensity of Fas-mediated intracellular signals determine life and death in T cells., PMID:20658220

Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells., PMID:20530686

Tumor necrosis factor stimulates matrix metalloproteinase 9 secretion from cultured human chorionic trophoblast cells through TNF receptor 1 signaling to IKBKB-NFKB and MAPK1/3 pathway., PMID:20463356

Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort., PMID:20353580

The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register., PMID:20219786

Chemical biology strategy reveals pathway-selective inhibitor of NF-kappaB activation induced by protein kinase C., PMID:20141195

[Is rheumatoid arthritis without anti-citrullinated peptide antibody a genetically distinct subset?]., PMID:20046016

Identification of candidate genes for rituximab response in rheumatoid arthritis patients by microarray expression profiling in blood cells., PMID:19842941

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci., PMID:19741008

Adiponectin inhibits pro-inflammatory signaling in human macrophages independent of interleukin-10., PMID:19617629

Lymphocyte-rich classical Hodgkin's lymphoma: distinctive tumor and microenvironment markers., PMID:19465900

Confirmation of STAT4, IL2/IL21, and CTLA4 polymorphisms in rheumatoid arthritis., PMID:19404967

Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis., PMID:19401279

Datasheet

Document Download

Anti-TRAF1 Antibody (R3S05).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Anti-TRAF1 Antibody (R3S05) [RHG39301]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only