Catalog No.
RHG20802
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:1000
Target
Neuroblast differentiation-associated protein AHNAK, PM227, AHNAK, Desmoyokin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q09666
Applications
ELISA, FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3R76
Single-cell transcriptomic analysis reveals distinct plasma cell populations in chronic thromboembolic pulmonary hypertension., PMID:39965671
The Bioactive Peptide SL-13R Expands Human Umbilical Cord Blood Hematopoietic Stem and Progenitor Cells In Vitro., PMID:33915948
Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons., PMID:33859650
Genomic Mapping Identifies Mutations in RYR2 and AHNAK as Associated with Favorable Outcome in Basal-Like Breast Tumors Expressing PD1/PD-L1., PMID:32796628
Ahnak-knockout mice show susceptibility to Bartonella henselae infection because of CD4+ T cell inactivation and decreased cytokine secretion., PMID:30940323
CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth., PMID:30289973
Protective Function of Ahnak1 in Vascular Healing after Wire Injury., PMID:28468000
SUSD2 expression in high-grade serous ovarian cancer correlates with increased patient survival and defective mesothelial clearance., PMID:27775699
Huntingtin is associated with cytomatrix proteins at the presynaptic terminal., PMID:25461618
AHNAK is highly expressed and plays a key role in cell migration and invasion in mesothelioma., PMID:24253341
Function of Ahnak protein in aortic smooth muscle cell migration through Rac activation., PMID:23042471
Identification of a novel type of CA19-9 carrier in human bile and sera of cancer patients: an implication of the involvement in nonsecretory exocytosis., PMID:20954701
AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness., PMID:20833135
Presynaptic calcium channels and α3-integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone components., PMID:20731762
The regulated exocytosis of enlargeosomes is mediated by a SNARE machinery that includes VAMP4., PMID:18713833
Spinal cord injury-induced up-regulation of AHNAK, expressed in cells delineating cystic cavities, and associated with neoangiogenesis., PMID:16930430
Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays., PMID:16424057
Highly purified lipoteichoic acid from gram-positive bacteria induces in vitro blood-brain barrier disruption through glia activation: role of pro-inflammatory cytokines and nitric oxide., PMID:16343789
The carboxyl-terminal ahnak domain induces actin bundling and stabilizes muscle contraction., PMID:15001564
Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus., PMID:11866458
Multiple antibodies to titin immunoreact with AHNAK and localize to the mitotic spindle machinery., PMID:11746675
Signaling from beta-adrenoceptor to L-type calcium channel: identification of a novel cardiac protein kinase A target possessing similarities to AHNAK., PMID:10593863
Detection of antigens by immunofluorescence on ultrathin cryosections of skin., PMID:9815287
Desmoyokin/AHNAK protein localizes to the non-desmosomal keratinocyte cell surface of human epidermis., PMID:7769263
Regulation of translocation of the desmoyokin/AHNAK protein to the plasma membrane in keratinocytes by protein kinase C., PMID:7698224
Desmoyokin, a 680 kDa keratinocyte plasma membrane-associated protein, is homologous to the protein encoded by human gene AHNAK., PMID:8408266
The human gene AHNAK encodes a large phosphoprotein located primarily in the nucleus., PMID:8381120