Catalog No.
RHG10503
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000
Target
Thioredoxin-dependent peroxide reductase 2, PAGB, Thioredoxin peroxidase 2, Proliferation-associated gene protein, Thioredoxin-dependent peroxiredoxin 1, PAG, PAGA, Peroxiredoxin-1, Natural killer cell-enhancing factor A, TDPX2, NKEF-A, PRDX1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q06830
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3R42
Discovery of indole analogue Tc3 as a potent pyroptosis inducer and identification of its combination strategy against hepatic carcinoma., PMID:39816682
Extracellular Prdx1 mediates bacterial infection and inflammatory bone diseases., PMID:37797684
Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-κB signaling., PMID:37164261
Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto's Thyroiditis., PMID:33916948
The prognostic value of JUNB-positive CTCs in metastatic breast cancer: from bioinformatics to phenotypic characterization., PMID:31370904
Tumor cells induce LAMP2a expression in tumor-associated macrophage for cancer progression., PMID:30711520
Multiple reaction monitoring targeted LC-MS analysis of potential cell death marker proteins for increased bioprocess control., PMID:29607450
Stimulatory function of peroxiredoxin 1 in activating adaptive humoral immunity in a zebrafish model., PMID:29518406
Peroxiredoxin I expression in epithelial cells of buccal mucosa from patients exposed to panoramic X-rays: influence of the age., PMID:29063384
Upregulation of thioredoxin-1 in activated human NK cells confers increased tolerance to oxidative stress., PMID:28224212
Peroxiredoxin 1 induces inflammatory cytokine response and predicts outcome of cardiogenic shock patients necessitating extracorporeal membrane oxygenation: an observational cohort study and translational approach., PMID:27142532
Reactive oxygen species mediate oxaliplatin-induced epithelial-mesenchymal transition and invasive potential in colon cancer., PMID:26733168
Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells., PMID:26094816
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer., PMID:25011585
Cancer-derived immunoglobulin G promotes tumor cell growth and proliferation through inducing production of reactive oxygen species., PMID:24309932
Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma., PMID:24009050
Stromal response to prostate cancer: nanotechnology-based detection of thioredoxin-interacting protein partners distinguishes prostate cancer associated stroma from that of benign prostatic hyperplasia., PMID:23762225
Expression of peroxiredoxins I and IV in multiple myeloma: association with immunoglobulin accumulation., PMID:23737084
Role of proinflammatory CD68(+) mannose receptor(-) macrophages in peroxiredoxin-1 expression and in abdominal aortic aneurysms in humans., PMID:23241402
Cross-reactive antibodies to target proteins are dependent upon oligomannose glycosylated epitopes in HTLV-1 associated neurological disease., PMID:22392044
Using proteomic approach to identify tumor-associated proteins as biomarkers in human esophageal squamous cell carcinoma., PMID:21517111
Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer., PMID:21165559
Proteomics characterization of cell model with renal fibrosis phenotype: osmotic stress as fibrosis triggering factor., PMID:21118732
Proteomic analysis in cyclosporin A-induced overgrowth of human gingival fibroblasts., PMID:19652395
Production and radioimmunoimaging of novel fully human phage display recombinant antibodies and growth inhibition of lung adenocarcinoma cell line overexpressing Prx I., PMID:19556853
Novel protective mechanism against irreversible hyperoxidation of peroxiredoxin: Nalpha-terminal acetylation of human peroxiredoxin II., PMID:19286652
Hepatocytes proteomic alteration and seroproteome analysis of HBV-transgenic mice., PMID:19053081
Post-translational glycosylation of target proteins implicate molecular mimicry in the pathogenesis of HTLV-1 associated neurological disease., PMID:18793806
Peroxiredoxin I is differentially expressed in multiple myelomas and in plasmablastic lymphomas., PMID:18565146
Increase in expression levels and resistance to sulfhydryl oxidation of peroxiredoxin isoforms in amyloid beta-resistant nerve cells., PMID:17761673
Immunohistochemical localization of 2-Cys peroxiredoxins in human ciliary body., PMID:17707450
Histological recovery of the hepatocytes is based on the redox system upregulation in the animal models of mutant superoxide dismutase (SOD)1-linked amyotrophic lateral sclerosis., PMID:16598672
Comparative proteomic analysis identifies protein disulfide isomerase and peroxiredoxin 1 as new players involved in embryonic interdigital cell death., PMID:15858817
Expression of peroxiredoxins in bovine oocytes and embryos produced in vitro., PMID:15349835