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Anti-FMR1 Antibody (R3R41)

Catalog #:   RHG10304 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IF, IHC, WB
Accession: Q06787
Overview

Catalog No.

RHG10304

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Fragile X mental retardation protein 1, Synaptic functional regulator FMR1, FMR1, Protein FMR-1, FMRP

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q06787

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3R41

Data Image
  • Immunofluorescence
    Immunofluorescence analysis of NIH/3T3 cells using FMR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human brain tissues, showing cytoplasmic localization with DAB staining using FMR1 mouse mAb.
  • Western blot
    Western blot analysis using FMR1 mouse mAb against Jurkat (1) and K562 (2) cell lysate.
References

Improving diagnostic precision in primary ovarian insufficiency using comprehensive genetic and autoantibody testing., PMID:37953503

Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development., PMID:37228035

Combined DiI and Antibody Labeling Reveals Complex Dysgenesis of Hippocampal Dendritic Spines in a Mouse Model of Fragile X Syndrome., PMID:36359212

m6A methylation regulators as predictors for treatment of advanced urothelial carcinoma with anti-PDL1 agent., PMID:36189296

Lysine acetylome profiling in mouse hippocampus and its alterations upon FMRP deficiency linked to abnormal energy metabolism., PMID:36089189

Development of a Quantitative FMRP Assay for Mouse Tissue Applications., PMID:34680911

Adult-onset neuronal intranuclear inclusion disease, with both stroke-like onset and encephalitic attacks: a case report., PMID:33789591

Neuronal intranuclear inclusion disease: two case report and literature review., PMID:32839883

[Relationship of the ovarian reserve with autoimmune thyroid diseases in the reproductive period]., PMID:32598626

Abnormal development of auditory responses in the inferior colliculus of a mouse model of Fragile X Syndrome., PMID:32319849

Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus., PMID:31853374

Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome., PMID:31665086

Multifaceted Changes in Synaptic Composition and Astrocytic Involvement in a Mouse Model of Fragile X Syndrome., PMID:31554841

Primary ovarian insufficiency in an adolescent population: clinical phenotype and diagnostic approach., PMID:31301677

Microglial cell activation and senescence are characteristic of the pathology FXTAS., PMID:30537011

Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain., PMID:30224722

Analysis of microRNA expression in the thymus of Myasthenia Gravis patients opens new research avenues., PMID:29655674

Menstrual cycle characteristics of young females with occult primary ovarian insufficiency at initial diagnosis and one-year follow-up with serum amh level and antral follicle count., PMID:29176793

Elevated progranulin contributes to synaptic and learning deficit due to loss of fragile X mental retardation protein., PMID:29096020

Molecular dynamics of FMRP and other RNA-binding proteins in MEG-01 differentiation: the role of mRNP complexes in non-neuronal development., PMID:27860518

Optimization of PAR-CLIP for transcriptome-wide identification of binding sites of RNA-binding proteins., PMID:27765618

Repeat-associated non-AUG translation from antisense CCG repeats in fragile X tremor/ataxia syndrome., PMID:27761921

[Analysis of CGG repeat instability in germline cells from two male fetuses affected with fragile X syndrome]., PMID:27577204

Comparison of Equivalence between Two Commercially Available S499-Phosphorylated FMRP Antibodies in Mice., PMID:26580204

Presence of inclusions positive for polyglycine containing protein, FMRpolyG, indicates that repeat-associated non-AUG translation plays a role in fragile X-associated primary ovarian insufficiency., PMID:26537920

Anti-neuronal antibodies in patients with fragile X syndrome: is there a role of autoimmunity in its pathogenesis?, PMID:25500855

Distribution of fragile X mental retardation protein in the human auditory brainstem., PMID:24838064

Tissue plasminogen activator contributes to alterations of neuronal migration and activity-dependent responses in fragile X mice., PMID:24478370

Identification and characterisation of Simiate, a novel protein linked to the fragile X syndrome., PMID:24349419

Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies., PMID:24204304

[Premature ovarian failures]., PMID:24157186

Primary ovarian insufficiency in the adolescent., PMID:24018874

Fragile X screening by quantification of FMRP in dried blood spots by a Luminex immunoassay., PMID:23660422

A quantitative homogeneous assay for fragile X mental retardation 1 protein., PMID:23548045

The role of genetic and autoimmune factors in premature ovarian failure., PMID:23504400

Excessive astrocyte-derived neurotrophin-3 contributes to the abnormal neuronal dendritic development in a mouse model of fragile X syndrome., PMID:23300470

An update on primary ovarian insufficiency., PMID:22932883

Distribution and frequency of intranuclear inclusions in female CGG KI mice modeling the fragile X premutation., PMID:22796595

Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected]., PMID:22737234

Expression, identification and purification of human FMRP isoform 10., PMID:22652662

Fragile X protein expression is linked to visual functions in healthy male volunteers., PMID:21749915

Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2., PMID:21490210

Open-label add-on treatment trial of minocycline in fragile X syndrome., PMID:20937127

FMR1 protein expression in blood smears for fragile X syndrome diagnosis in a Mexican population sample., PMID:20642356

A functional requirement for PAK1 binding to the KH(2) domain of the fragile X protein-related FXR1., PMID:20417602

The significance of the number of CGG repeats and autoantibodies in premature ovarian failure., PMID:20362512

Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila., PMID:20122915

Do etiologies of premature ovarian aging (POA) mimic those of premature ovarian failure (POF)?, PMID:19617205

Premature ovarian failure., PMID:19461434

You can build it ... but will they come?: the potential "expansion" of testing methodologies for fragile X syndrome., PMID:19460939

Datasheet

Document Download

Anti-FMR1 Antibody (R3R41).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-FMR1 Antibody (R3R41) [RHG10304]
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