Catalog No.
RHG10304
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Fragile X mental retardation protein 1, Synaptic functional regulator FMR1, FMR1, Protein FMR-1, FMRP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q06787
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3R41
Improving diagnostic precision in primary ovarian insufficiency using comprehensive genetic and autoantibody testing., PMID:37953503
Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development., PMID:37228035
Combined DiI and Antibody Labeling Reveals Complex Dysgenesis of Hippocampal Dendritic Spines in a Mouse Model of Fragile X Syndrome., PMID:36359212
m6A methylation regulators as predictors for treatment of advanced urothelial carcinoma with anti-PDL1 agent., PMID:36189296
Lysine acetylome profiling in mouse hippocampus and its alterations upon FMRP deficiency linked to abnormal energy metabolism., PMID:36089189
Development of a Quantitative FMRP Assay for Mouse Tissue Applications., PMID:34680911
Adult-onset neuronal intranuclear inclusion disease, with both stroke-like onset and encephalitic attacks: a case report., PMID:33789591
Neuronal intranuclear inclusion disease: two case report and literature review., PMID:32839883
[Relationship of the ovarian reserve with autoimmune thyroid diseases in the reproductive period]., PMID:32598626
Abnormal development of auditory responses in the inferior colliculus of a mouse model of Fragile X Syndrome., PMID:32319849
Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus., PMID:31853374
Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome., PMID:31665086
Multifaceted Changes in Synaptic Composition and Astrocytic Involvement in a Mouse Model of Fragile X Syndrome., PMID:31554841
Primary ovarian insufficiency in an adolescent population: clinical phenotype and diagnostic approach., PMID:31301677
Microglial cell activation and senescence are characteristic of the pathology FXTAS., PMID:30537011
Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain., PMID:30224722
Analysis of microRNA expression in the thymus of Myasthenia Gravis patients opens new research avenues., PMID:29655674
Menstrual cycle characteristics of young females with occult primary ovarian insufficiency at initial diagnosis and one-year follow-up with serum amh level and antral follicle count., PMID:29176793
Elevated progranulin contributes to synaptic and learning deficit due to loss of fragile X mental retardation protein., PMID:29096020
Molecular dynamics of FMRP and other RNA-binding proteins in MEG-01 differentiation: the role of mRNP complexes in non-neuronal development., PMID:27860518
Optimization of PAR-CLIP for transcriptome-wide identification of binding sites of RNA-binding proteins., PMID:27765618
Repeat-associated non-AUG translation from antisense CCG repeats in fragile X tremor/ataxia syndrome., PMID:27761921
[Analysis of CGG repeat instability in germline cells from two male fetuses affected with fragile X syndrome]., PMID:27577204
Comparison of Equivalence between Two Commercially Available S499-Phosphorylated FMRP Antibodies in Mice., PMID:26580204
Presence of inclusions positive for polyglycine containing protein, FMRpolyG, indicates that repeat-associated non-AUG translation plays a role in fragile X-associated primary ovarian insufficiency., PMID:26537920
Anti-neuronal antibodies in patients with fragile X syndrome: is there a role of autoimmunity in its pathogenesis?, PMID:25500855
Distribution of fragile X mental retardation protein in the human auditory brainstem., PMID:24838064
Tissue plasminogen activator contributes to alterations of neuronal migration and activity-dependent responses in fragile X mice., PMID:24478370
Identification and characterisation of Simiate, a novel protein linked to the fragile X syndrome., PMID:24349419
Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies., PMID:24204304
[Premature ovarian failures]., PMID:24157186
Primary ovarian insufficiency in the adolescent., PMID:24018874
Fragile X screening by quantification of FMRP in dried blood spots by a Luminex immunoassay., PMID:23660422
A quantitative homogeneous assay for fragile X mental retardation 1 protein., PMID:23548045
The role of genetic and autoimmune factors in premature ovarian failure., PMID:23504400
Excessive astrocyte-derived neurotrophin-3 contributes to the abnormal neuronal dendritic development in a mouse model of fragile X syndrome., PMID:23300470
An update on primary ovarian insufficiency., PMID:22932883
Distribution and frequency of intranuclear inclusions in female CGG KI mice modeling the fragile X premutation., PMID:22796595
Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected]., PMID:22737234
Expression, identification and purification of human FMRP isoform 10., PMID:22652662
Fragile X protein expression is linked to visual functions in healthy male volunteers., PMID:21749915
Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2., PMID:21490210
Open-label add-on treatment trial of minocycline in fragile X syndrome., PMID:20937127
FMR1 protein expression in blood smears for fragile X syndrome diagnosis in a Mexican population sample., PMID:20642356
A functional requirement for PAK1 binding to the KH(2) domain of the fragile X protein-related FXR1., PMID:20417602
The significance of the number of CGG repeats and autoantibodies in premature ovarian failure., PMID:20362512
Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila., PMID:20122915
Do etiologies of premature ovarian aging (POA) mimic those of premature ovarian failure (POF)?, PMID:19617205
Premature ovarian failure., PMID:19461434
You can build it ... but will they come?: the potential "expansion" of testing methodologies for fragile X syndrome., PMID:19460939