Catalog No.
RHG08704
Species reactivity
Human, Mouse, Rat, Rabbit, Monkey
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:100-1:500, WB: 1:500-1:2000
Target
MEF2C, Myocyte-specific enhancer factor 2C, Myocyte enhancer factor 2C
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q06413
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3R26
Integrative miRNA-mRNA profiling uncovers mechanisms of belimumab action in systemic lupus erythematosus., PMID:40160819
Single-Cell Transcriptomics Identifies Selective Lineage-Specific Regulation of Genes in Aortic Smooth Muscle Cells in Mice., PMID:39744838
METTL3 promotes microglial inflammation via MEF2C in spinal cord injury., PMID:38180567
Emerging role for thymic stromal lymphopoietin-responsive regulatory T cells in colorectal cancer progression in humans and mice., PMID:35584230
Discovery of Novel Circulating Immune Complexes in Lupus Nephritis Using Immunoproteomics., PMID:35419005
The Cell Adhesion Molecule L1 Interacts with Methyl CpG Binding Protein 2 via Its Intracellular Domain., PMID:35408913
Comparing the epigenetic landscape in myonuclei purified with a PCM1 antibody from a fast/glycolytic and a slow/oxidative muscle., PMID:34752468
MiR-96-5p Induced by Palmitic Acid Suppresses the Myogenic Differentiation of C2C12 Myoblasts by Targeting FHL1., PMID:33322515
Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma., PMID:33094287
Loss of Mef2D function enhances TLR induced IL-10 production in macrophages., PMID:32725155
Nerve impulse transmission pathway-focused genes expression analysis in patients with primary hypothyroidism and autoimmune thyroiditis., PMID:32597152
B Cell Development sans B Cell Receptor Responsiveness Due to Unfolded Protein Response-Triggered Mef2c Protein Degradation., PMID:30305329
Isolation, Characterization and Differentiation of Mouse Cardiac Progenitor Cells., PMID:30196409
Comparative analysis of histologically classified oligodendrogliomas reveals characteristic molecular differences between subgroups., PMID:29631562
Trichinella spiralis muscle larvae excretory-secretory products induce changes in cytoskeletal and myogenic transcription factors in primary myoblast cultures., PMID:29258830
Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts., PMID:28362413
High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group., PMID:26487643
Analysis of SOST expression using large minigenes reveals the MEF2C binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D3 or TGFβ1 responsiveness., PMID:26361013
Adipose-derived stem cell adhesion on laminin-coated microcarriers improves commitment toward the cardiomyogenic lineage., PMID:25098676
Islet-1 may function as an assistant factor for histone acetylation and regulation of cardiac development-related transcription factor Mef2c expression., PMID:24147056
HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia., PMID:23888946
Accelerated direct reprogramming of fibroblasts into cardiomyocyte-like cells with the MyoD transactivation domain., PMID:23794713
In vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factor., PMID:23316332
Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin., PMID:22927401
Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells., PMID:22884695
Developmentally regulated expression of MEF2C limits the response to BCR engagement in transitional B cells., PMID:22311635
Potential characteristics of stem cells from human exfoliated deciduous teeth compared with bone marrow-derived mesenchymal stem cells for mineralized tissue-forming cell biology., PMID:22099898
HDAC inhibition promotes cardiogenesis and the survival of embryonic stem cells through proteasome-dependent pathway., PMID:21751234
Analysis of the chondrogenic potential and secretome of mesenchymal stem cells derived from human umbilical cord stroma., PMID:20977334
Sodium arsenite delays the differentiation of C2C12 mouse myoblast cells and alters methylation patterns on the transcription factor myogenin., PMID:20965206
Activity assays for extracellular signal-regulated kinase 5., PMID:20811978
A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression., PMID:20447394
The calcineurin-myocyte enhancer factor 2c pathway mediates cardiac hypertrophy induced by endoplasmic reticulum stress in neonatal rat cardiomyocytes., PMID:20207814
Co-culture with cardiomyocytes enhanced the myogenic conversion of mesenchymal stromal cells in a dose-dependent manner., PMID:20063193
Protection of retinal ganglion cells by caspase substrate-binding peptide IQACRG from N-methyl-D-aspartate receptor-mediated excitotoxicity., PMID:19815732
A p38 MAPK-MEF2C pathway regulates B-cell proliferation., PMID:18955699
Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation., PMID:18438409
Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis., PMID:18252802
STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction., PMID:17823373
Control of the SOST bone enhancer by PTH using MEF2 transcription factors., PMID:17696759
Differentiation in vivo of cardiac committed human embryonic stem cells in postmyocardial infarcted rats., PMID:17540853
Peroxisome proliferator-activated receptor alpha is involved in cardiomyocyte differentiation of murine embryonic stem cells in vitro., PMID:17467307
TACE release of TNF-alpha mediates mechanotransduction-induced activation of p38 MAPK and myogenesis., PMID:17264149
TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK., PMID:17151142
HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage., PMID:17038545
MEF2C DNA-binding activity is inhibited through its interaction with the regulatory protein Ki-1/57., PMID:15862299
Sequestration of pRb by cyclin D3 causes intranuclear reorganization of lamin A/C during muscle cell differentiation., PMID:15703219
Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes., PMID:12408979
The C-terminus of myogenin, but not MyoD, targets upregulation of MEF2C expression., PMID:12135755
Functional regulatory regions of human transcription factor MEF2C., PMID:11744164
For research use only. Not for human or drug use.
