Catalog No.
RHG04003
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
Oncogenic protein-associated protein E6-AP, Ubiquitin-protein ligase E3A, UBE3A, E6AP ubiquitin-protein ligase, HPVE6A, EPVE6AP, HECT-type ubiquitin transferase E3A, E6AP, Human papillomavirus E6-associated protein, Renal carcinoma antigen NY-REN-54
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q05086
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3R09
A high sensitivity assay of UBE3A ubiquitin ligase activity., PMID:39933617
Effects of UBE3A on Cell and Liver Metabolism through the Ubiquitination of PDHA1 and ACAT1., PMID:36920305
Regulation of O-Linked N-Acetyl Glucosamine Transferase (OGT) through E6 Stimulation of the Ubiquitin Ligase Activity of E6AP., PMID:34638625
Evaluation of UBE3A antibodies in mice and human cerebral organoids., PMID:33737669
The ubiquitin-protein ligase E6AP/UBE3A supports early encephalomyocarditis virus replication., PMID:29782878
Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer., PMID:29263404
Persistent neuronal Ube3a expression in the suprachiasmatic nucleus of Angelman syndrome model mice., PMID:27306933
Proteomic discovery of MNT as a novel interacting partner of E3 ubiquitin ligase E6AP and a key mediator of myeloid differentiation., PMID:26506232
Polyreactivity and autoreactivity among HIV-1 antibodies., PMID:25355869
Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A., PMID:24706802
E6-associated protein is required for human papillomavirus type 16 E6 to cause cervical cancer in mice., PMID:20530688
Evaluation of different glutathione S-transferase-tagged protein captures for screening E6/E6AP interaction inhibitors using AlphaScreen., PMID:17478484
Binding of human papillomavirus 16 E6 to p53 and E6AP is impaired by monoclonal antibodies directed against the second zinc-binding domain of E6., PMID:15784893
Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3., PMID:15615769
Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a., PMID:12668607
Characterization of the interactions of human papillomavirus type 16 E6 with p53 and E6-associated protein in insect and human cells., PMID:9519827
Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP)., PMID:7724550
For research use only. Not for human or drug use.
