Anti-c-Rel Antibody (R3R06)

Catalog No.

RHG03202

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

REL, Proto-oncogene c-Rel

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q04864

Applications

ELISA, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3R06

Identification of two novel variants, c.-35A>T and c.[-35A>T, 725T>G], in the FUT1 gene in a patient exhibiting the para-Bombay phenotype., PMID:39473114

NrCAM activates the NF-κB signalling pathway by competitively binding to SUMO-1 and promotes Th17 cell differentiation in Graves' disease., PMID:39155774

Direct observation correlates NFκB cRel in B cells with activating and terminating their proliferative program., PMID:39024115

Metformin targets intestinal immune system signaling pathways in a high-fat diet-induced mouse model of obesity and insulin resistance., PMID:37795356

The regulatory effect of NF-κB signaling pathway on biomineralization and shell regeneration in pearl oyster, Pinctada fucata., PMID:37739291

Toll-like receptor mediated inflammation directs B cells towards protective antiviral extrafollicular responses., PMID:37407556

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy., PMID:37337107

Disaccharide-tag for highly sensitive identification of O-GlcNAc-modified proteins in mammalian cells., PMID:35604954

Artificial Neural Networks Predicted the Overall Survival and Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Pancancer Immune-Oncology Panel., PMID:34945004

Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases., PMID:34877502

Transcription factor c-Rel mediates communication between commensal bacteria and mucosal lymphocytes., PMID:34622991

Targeting NF-κB c-Rel in regulatory T cells to treat corneal transplantation rejection., PMID:34254428

T and B Lymphocyte Transcriptional States Differentiate between Sensitized and Unsensitized Individuals in Alpha-Gal Syndrome., PMID:33804792

AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeys., PMID:32886754

cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis., PMID:32725139

Inhibition of IL-2 or NF-κB Subunit c-Rel-Dependent Signaling Inhibits Expansion of Regulatory T Cells During Acute Friend Retrovirus Infection., PMID:32315584

BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells., PMID:32294437

miR-146a in Myasthenia Gravis Thymus Bridges Innate Immunity With Autoimmunity and Is Linked to Therapeutic Effects of Corticosteroids., PMID:32210951

c-Rel gain in B cells drives germinal center reactions and autoantibody production., PMID:32191641

Treating Autoimmune Diseases by Targeting IL-23 with Gene-Silencing Pyrrole-Imidazole Polyamide., PMID:32169850

Regulation of B-cell function by NF-kappaB c-Rel in health and disease., PMID:32130429

The NF-κB transcription factor c-Rel controls host defense against Citrobacter rodentium., PMID:31724737

Clinical and molecular characteristics of lymphoplasmacytic lymphoma not associated with an IgM monoclonal protein: A multicentric study of the Rete Ematologica Lombarda (REL) network., PMID:31378966

Responsiveness of chronic lymphocytic leukemia cells to B-cell receptor stimulation is associated with low expression of regulatory molecules of the nuclear factor-κB pathway., PMID:31097630

siRNA-mediated c-Rel knockdown ameliorates collagen-induced arthritis in mice., PMID:29324391

Dietary pyridoxine deficiency reduced growth performance and impaired intestinal immune function associated with TOR and NF-κB signalling of young grass carp (Ctenopharyngodon idella)., PMID:28951222

Gastrointestinal Microbiome Dysbiosis in Infant Mice Alters Peripheral CD8+ T Cell Receptor Signaling., PMID:28337207

Silencing c-Rel in macrophages dampens Th1 and Th17 immune responses and alleviates experimental autoimmune encephalomyelitis in mice., PMID:28202908

Functional promoter polymorphisms direct the expression of cystathionine gamma-lyase gene in mouse models of essential hypertension., PMID:27865915

Differential requirements for the canonical NF-κB transcription factors c-REL and RELA during the generation and activation of mature B cells., PMID:27649781

Treating psoriasis by targeting its susceptibility gene Rel., PMID:26993753

Genetic variants associated with rheumatoid arthritis patients and serotypes in European populations., PMID:26939566

The Mycobacterium tuberculosis relBE toxin:antitoxin genes are stress-responsive modules that regulate growth through translation inhibition., PMID:26502963

Extracellular histones induce tissue factor expression in vascular endothelial cells via TLR and activation of NF-κB and AP-1., PMID:26476743

The AhR and NF-κB/Rel Proteins Mediate the Inhibitory Effect of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on the 3' Immunoglobulin Heavy Chain Regulatory Region., PMID:26377645

Impact of loss of NF-κB1, NF-κB2 or c-REL on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice., PMID:26084385

The c-Rel subunit of NF-κB is a crucial regulator of phenotype and motility of HaCaT keratinocytes., PMID:25842167

Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction., PMID:25756944

Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin., PMID:25681334

Imipramine exploits histone deacetylase 11 to increase the IL-12/IL-10 ratio in macrophages infected with antimony-resistant Leishmania donovani and clears organ parasites in experimental infection., PMID:25217162

Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits., PMID:25180063

Involvement of the NF-кB/p50/Bcl-3 complex in response to antiangiogenic therapy in a mouse model of metastatic renal cell carcinoma., PMID:25113400

Transcription factors involved in prostate gland adaptation to androgen deprivation., PMID:24886974

Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth., PMID:24529102

Critical Role of Glycogen Synthase Kinase-3β in Regulating the Avian Heterophil Response to Salmonella enterica Serovar Enteritidis., PMID:26664916

Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63., PMID:23710361

Potential celiac patients: a model of celiac disease pathogenesis., PMID:21760890

Genetic variability in the major capsid L1 protein of human papillomavirus type 16 (HPV-16) and 18 (HPV-18)., PMID:21729769

Tissue factor-factor VIIa complex induces epithelial ovarian cancer cell invasion and metastasis through a monocytes-dependent mechanism., PMID:21543928

Evolution and comparative genomics of subcellular specializations: EST sequencing of Torpedo electric organ., PMID:21429463

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