Catalog No.
RHF98301
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, WB: 1:500-1:2000
Target
TGFBR3, TGF-beta receptor type III, Transforming growth factor beta receptor type 3, TGFR-3, Betaglycan, TGF-beta receptor type 3, Transforming growth factor beta receptor III
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q03167
Applications
ELISA, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Q77
Stabilisation of extracellular matrix is crucial to rapamycin-mediated life span increase in Marfan mgR/mgR mice., PMID:40021021
Efficacy of Immunization against a Novel Synthetic 13-Amino Acid Betaglycan-Binding Peptide Sequence of Inhibin α Subunit on Promoting Fertility in Female Rats., PMID:37108077
["New antigens" in membranous glomerulonephritis: let's take a closer look]., PMID:36563071
Transforming Growth Factor Beta Receptor 3 (TGFBR3)-Associated Membranous Nephropathy., PMID:35369660
Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry., PMID:33626330
Myxoinflammatory fibroblastic sarcoma: an immunohistochemical and molecular genetic study of 73 cases., PMID:32514165
A Tale of Two Proteins: Betaglycan, IGSF1, and the Continuing Search for the Inhibin B Receptor., PMID:31648935
Betaglycan drives the mesenchymal stromal cell osteogenic program and prostate cancer-induced osteogenesis., PMID:31409900
Extracellular Vesicles from Wharton's Jelly Mesenchymal Stem Cells Suppress CD4 Expressing T Cells Through Transforming Growth Factor Beta and Adenosine Signaling in a Canine Model., PMID:30412034
Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling., PMID:29221447
Affinity Labeling Detection of Endogenous Receptors from Zebrafish Embryos., PMID:27685504
Retinoic acid enhances lactoferrin-induced IgA responses by increasing betaglycan expression., PMID:26277894
Proteins interaction network and modeling of IGVH mutational status in chronic lymphocytic leukemia., PMID:26088082
Surrogate molecular markers for IGHV mutational status in chronic lymphocytic leukemia for predicting time to first treatment., PMID:26038121
Immunohistochemical protein expression profiling of growth- and apoptotic-related factors in relation to umbilical cord length., PMID:25804127
Evaluation of a special combination of glucan with organic selenium derivative in different murine tumor models., PMID:25503119
Lactoferrin causes IgA and IgG2b isotype switching through betaglycan binding and activation of canonical TGF-β signaling., PMID:25492477
Mating decreases plasma levels of TGFβ1 and regulates myosalpinx expression of TGFβ1/TGFBR3 in the rat., PMID:25359088
The characterization of IgG antibodies to GalNAc beta-terminated glycans of gastric cancer survivors., PMID:24691283
Paracrine regulation of theca androgen production by granulosa cells in the ovary., PMID:23706336
Effect of TGF-β on ocular surface epithelial cells., PMID:23220729
Expression of inhibin/activin proteins and receptors in the human hypothalamus and basal forebrain., PMID:22296042
Inhibin α-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling., PMID:22267736
Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 pathway., PMID:22227366
Glycomic analyses of ovarian follicles during development and atresia., PMID:22057033
Elevated CCN2 expression in scleroderma: a putative role for the TGFβ accessory receptors TGFβRIII and endoglin., PMID:21769684
Fibroblast growth factor-2 promotes in vitro mitral valve interstitial cell repair through transforming growth factor-β/Smad signaling., PMID:21224050
Recent insights into diabetic renal injury from the db/db mouse model of type 2 diabetic nephropathy., PMID:21147843
Fibroblast and prostate tumor cell cross-talk: fibroblast differentiation, TGF-β, and extracellular matrix down-regulation., PMID:20727350
Association between genetic variations of the transforming growth factor ß receptor type III and asthma in a Korean population., PMID:20386084
Fetal testis dysgenesis and compromised Leydig cell function in Tgfbr3 (beta glycan) knockout mice., PMID:19696014
Endogenous betaglycan is essential for high-potency inhibin antagonism in gonadotropes., PMID:19372236
Hyperinsulinemic hypoglycemia with nesidioblastosis: histologic features and growth factor expression., PMID:18931647
Syndecan-1/CD147 association is essential for cyclophilin B-induced activation of p44/42 mitogen-activated protein kinases and promotion of cell adhesion and chemotaxis., PMID:17267519
A "traffic control" role for TGFbeta3: orchestrating dermal and epidermal cell motility during wound healing., PMID:16549496
Neurogenic niche modulation by activated microglia: transforming growth factor beta increases neurogenesis in the adult dentate gyrus., PMID:16420418
Betaglycan induces TGF-beta signaling in a ligand-independent manner, through activation of the p38 pathway., PMID:16413747
Identification of endoglin in rat hepatic stellate cells: new insights into transforming growth factor beta receptor signaling., PMID:15537649
Systemic administration of a soluble betaglycan suppresses tumor growth, angiogenesis, and matrix metalloproteinase-9 expression in a human xenograft model of prostate cancer., PMID:15468171
Exogenous modulation of TGF-beta(1) influences TGF-betaR-III-associated vascularization during wound healing in irradiated tissue., PMID:15292974
CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells., PMID:15130945
Large matrix proteoglycans, versican and perlecan, are expressed and secreted by human leukemic monocytes., PMID:12926067
Autocrine TGFbeta supports growth and survival of human breast cancer MDA-MB-231 cells., PMID:12386814
Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways., PMID:12063164
TGFbeta Type III and TGFbeta Type II receptors have distinct activities during epithelial-mesenchymal cell transformation in the embryonic heart., PMID:11500982
Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent., PMID:11256966
Identification of specific inhibin A-binding proteins on mouse Leydig (TM3) and sertoli (TM4) cell lines., PMID:11250918
Expression and distribution of cell-surface proteoglycans in the normal Lewis rat molar periodontium., PMID:10983882
Transforming growth factor-beta receptor types I and II in cultured porcine leydig cells: expression and hormonal regulation., PMID:10830292
Taenia crassiceps cysticercosis: protective effect and immune response elicited by DNA immunization., PMID:10701566