Catalog No.
RHF89101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
IP: 1:100-1:200, WB: 1:500-1:1000
Target
PMSCL2, EXOSC10, Exosome component 10, P100 polymyositis-scleroderma overlap syndrome-associated autoantigen, PM/Scl-100, Autoantigen PM/Scl 2, PMSCL, Polymyositis/scleroderma autoantigen 100 kDa, Polymyositis/scleroderma autoantigen 2, RRP6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q01780
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Q41
Patients with anti-PM/Scl-positive and idiopathic inflammatory myopathy resemble anti-synthetase syndrome., PMID:39953567
Clinical characteristics of idiopathic inflammatory myopathies patients with anti-PM/Scl antibodies., PMID:39178740
RNA exosome drives early B cell development via noncoding RNA processing mechanisms., PMID:35658015
The clinical phenotype of systemic sclerosis patients with anti-PM/Scl antibodies: results from the EUSTAR cohort., PMID:33580257
Autoantibodies in outbred Swiss Webster mice following exposure to gold and mercury., PMID:33358697
The Relationship Between Autonomic Dysfunction of the Gastrointestinal Tract and Emotional Distress in Patients With Systemic Sclerosis., PMID:31524844
High-throughput assessment of the antibody profile in ovarian cancer ascitic fluids., PMID:31428516
Performance evaluation of a line blot assay system for detection of anti-PM-Scl antibody in Japanese patients with systemic sclerosis., PMID:31245910
Clinical significance of autoantibodies in dermatomyositis and systemic sclerosis., PMID:30047434
Anti-PM/Scl antibody-positive dermatomyositis in a Japanese patient: a case report and review of the literature., PMID:28185425
Calcinosis in poly-dermatomyositis: clinical and laboratory predictors and treatment options., PMID:27908312
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis., PMID:26246178
RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity., PMID:25957685
Anti-SSA/Ro52 autoantibodies in scleroderma: results of an observational, cross-sectional study., PMID:25372801
Clinical and serologic correlates of anti-PM/Scl antibodies in systemic sclerosis: a multicenter study of 763 patients., PMID:24577935
Myopathy in scleroderma, its identification, prevalence, and treatment: lessons learned from cohort studies., PMID:24419752
Skin lesions in anti-Pm-Scl-70 positive systemic sclerosis-dermatomyositis overlap syndrome improve during local PUVA phototherapy., PMID:24126033
[Systemic sclerosis autoantibodies: what dermatologists must know]., PMID:23395500
Fluoroenzymeimmunoassay to detect systemic sclerosis-associated antibodies: diagnostic performance and correlation with conventional techniques., PMID:22765957
Evaluation of a new multi-parallel line immunoassay for systemic sclerosis-associated antibodies in an Asian population., PMID:22491717
Anti-PM-Scl antibody in patients with systemic sclerosis., PMID:22261302
Diagnostic assays for anti-PM/Scl IgG antibodies: heterogeneity in antibody response or lack of standardization?, PMID:21371448
[Anti-polymyositis-scleroderma(PM-Scl) antibody]., PMID:20942126
[How can we diagnose and better understand inflammatory myopathies? The usefulness of auto-antibodies]., PMID:20655695
[Idiopathic inflammatory myopathies with anti-PM-Scl antibodies: case series and literature review]., PMID:20510485
Anti-PM/Scl-100 and anti-RNA-polymerase III antibodies in scleroderma., PMID:20346932
Interstitial lung disease associated with anti-PM/Scl or anti-aminoacyl-tRNA synthetase autoantibodies: a similar condition?, PMID:20231208
Antibodies to fibrillarin, PM-Scl and RNA polymerase III detected by ELISA assays in patients with systemic sclerosis., PMID:20138166
The human exosome and disease., PMID:21618880
Long-term outcome of patients with polymyositis/ dermatomyositis and anti-PM-Scl antibody., PMID:19845665
HLA-DPB1 associations differ between DRB1*03 positive anti-Jo-1 and anti-PM-Scl antibody positive idiopathic inflammatory myopathy., PMID:19690132
The changing landscape of the clinical value of the PM/Scl autoantibody system., PMID:19351430
Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients., PMID:19220911
PM1-Alpha ELISA: the assay of choice for the detection of anti-PM/Scl autoantibodies?, PMID:19103309
Clinical significance of elevated antinuclear antibody test in patients with Hodgkin's and Non-Hodgkin's lymphoma: a single center experience., PMID:18299692
Myositis-specific and myositis-associated antibodies in a series of eighty-eight Mediterranean patients with idiopathic inflammatory myopathy., PMID:17013837
[Anti PM-Scl antibodies. Study of prevalence and of meaning]., PMID:16797795
Dysphagia associated with anti-PM-Scl antibodies in systemic lupus erythematosus., PMID:16641054
Childhood onset systemic sclerosis: classification, clinical and serologic features, and survival in comparison with adult onset disease., PMID:16583463
[PM-Scl antibody positive systemic sclerosis associated with inclusion-body myositis]., PMID:16244833
[Immunologic tests: Anti-polymyositis-scleroderma (PM-Scl) antibody]., PMID:16111314
Patients with antibodies to both PmScl and dsDNA., PMID:15517629
PM-Scl-75 is the main autoantigen in patients with the polymyositis/scleroderma overlap syndrome., PMID:14872500
Anti-PM-Scl antibodies in a patient with inclusion body myositis., PMID:12869677
Anti-Ku antibodies in connective tissue diseases: clinical and serological evaluation of 14 patients., PMID:12136894
Case 26-2001: scleroderma renal crisis and polymyositis., PMID:12063382
Autoantibodies directed to novel components of the PM/Scl complex, the human exosome., PMID:11879549
Acquired haemophilia and PM-Scl antibodies., PMID:10952757
Identification of an alpha-helical epitope region on the PM/Scl-100 autoantigen with structural homology to a region on the heterochromatin p25beta autoantigen using immobilized overlapping synthetic peptides., PMID:10759029
[Anti-PM-Scl antibody]., PMID:10635874
For research use only. Not for human or drug use.
