Catalog No.
RHF83004
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
Heat shock factor protein 1, HSF 1, HSTF 1, HSF1, HSTF1, Heat shock transcription factor 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q00613
Applications
ELISA, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Q16
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel., PMID:40449694
Children with hemoglobin C or S trait have low serologic responses to a subset of malaria variant surface antigens., PMID:39216830
Transglutaminase 2 Regulates HSF1 Gene Expression in the Acute Phase of Fish Optic Nerve Regeneration., PMID:39201764
ESCCPred: a machine learning model for diagnostic prediction of early esophageal squamous cell carcinoma using autoantibody profiles., PMID:38956246
Cytokine Levels in Experimental Branch Retinal Vein Occlusion Treated With Either Bevacizumab or Triamcinolone Acetonide., PMID:38899953
Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies., PMID:38086380
Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation., PMID:37120615
Emerging role of heat shock proteins in cardiovascular diseases., PMID:36858739
[Protective effect of heat shock transcription factor 1 on acute lung injury in septic rats by regulating NOD-like receptor protein 3 inflammasome activation]., PMID:36567560
Crosstalk between heat shock factor 1 and signal transducer and activator of transcription 3 mediated by interleukin-8 autocrine signaling maintains the cancer stem cell phenotype in liver cancer., PMID:36300571
Heat shock factor HSF1 regulates BDNF gene promoters upon acute stress in the hippocampus, together with pCREB., PMID:36227087
The Therapeutic Roles of Recombinant Hsp90α on Cornea Epithelial Injury., PMID:35201262
Distribution of serotypes and antibiotic resistance of invasive Pseudomonas aeruginosa in a multi-country collection., PMID:34991476
A phospho-proteomic study of cetuximab resistance in KRAS/NRAS/BRAFV600 wild-type colorectal cancer., PMID:34462871
Mapping Epitopes Recognised by Autoantibodies Shows Potential for the Diagnosis of High-Grade Serous Ovarian Cancer and Monitoring Response to Therapy for This Malignancy., PMID:34439354
A simplified and sensitive immunoprecipitation approach for the analysis of HSF1 in murine liver tissue., PMID:34434877
Targeting Cancer Metabolism Breaks Radioresistance by Impairing the Stress Response., PMID:34359663
A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice., PMID:33658297
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models., PMID:33619476
RNA aptamer capture of macromolecular complexes for mass spectrometry analysis., PMID:32609809
Epitope-based sieve analysis of Plasmodium falciparum sequences from a FMP2.1/AS02A vaccine trial is consistent with differential vaccine efficacy against immunologically relevant AMA1 variants., PMID:32571720
Identification of a novel autoantibody against heat shock factor 1 in idiopathic inflammatory myopathy., PMID:32141435
Inactivation of NF1 Promotes Resistance to EGFR Inhibition in KRAS/NRAS/BRAFV600 -Wild-Type Colorectal Cancer., PMID:32098826
Heat shock transcription factor 1 regulates exercise-induced myocardial angiogenesis after pressure overload via HIF-1α/VEGF pathway., PMID:31930683
Heat shock factor 4 regulates lysosome activity by modulating the αB-crystallin-ATP6V1A-mTOR complex in ocular lens., PMID:31786107
Heat shock transcription factor 1 affects kidney tubular cell migration by regulating the TGF‑β1‑Smad2/3 signaling pathway., PMID:31545442
Heat shock in C. elegans induces downstream of gene transcription and accumulation of double-stranded RNA., PMID:30958820
RNA interference may suppress stress granule formation by preventing argonaute 2 recruitment., PMID:30404558
CUB Domain-containing Protein 1 (CDCP1) Is Down-regulated by Active Hexose-correlated Compound in Human Pancreatic Cancer Cells., PMID:30396925
Proteomic analysis identifies NPTX1 and HIP1R as potential targets of histone deacetylase-3-mediated neurodegeneration., PMID:29486577
HSP70 Facilitates Memory Consolidation of Fear Conditioning through MAPK Pathway in the Hippocampus., PMID:29374537
FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice., PMID:29285313
Autoantibodies against HSF1 and CCDC155 as Biomarkers of Early-Stage, High-Grade Serous Ovarian Cancer., PMID:29141850
[Effect of heat shock factor 1 on airway hyperresponsiveness and airway inflammation in mice with allergic asthma]., PMID:28202124
Visualization of RAS/MAPK Signaling In Situ by the Proximity Ligation Assay (PLA)., PMID:27924568
High Estradiol Concentrations Induce Heat Shock Protein 70 Expression and Suppress Nuclear Factor Kappa B Activation in Human Endometrial Epithelial Cells., PMID:27605343
Compression loading-induced stress responses in intervertebral disc cells encapsulated in 3D collagen constructs., PMID:27197886
Heat shock factor 1 induces crystallin-αB to protect against cisplatin nephrotoxicity., PMID:27194715
Transthyretin Suppresses Amyloid-β Secretion by Interfering with Processing of the Amyloid-β Protein Precursor., PMID:27079720
Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab., PMID:26854735
Sulfide exposure results in enhanced sqr transcription through upregulating the expression and activation of HSF1 in echiuran worm Urechis unicinctus., PMID:26675369
Grating coupled SPR microarray analysis of proteins and cells in blood from mice with breast cancer., PMID:26539568
Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia., PMID:26397138
Defective heat shock factor 1 inhibits the growth of fibrosarcoma derived from simian virus 40/T antigen‑transformed MEF cells., PMID:26352782
Role of membrane Hsp70 in radiation sensitivity of tumor cells., PMID:26197988
When Cancer Fights Back: Multiple Myeloma, Proteasome Inhibition, and the Heat-Shock Response., PMID:26013169
Glucose regulates heat shock factor 1 transcription activity via mTOR pathway in HCC cell lines., PMID:26010766
Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis., PMID:25793532
Targeting of tumor-associated gangliosides with antibodies affects signaling pathways and leads to cell death including apoptosis., PMID:25673107
Upregulation of heat shock factor 1 transcription activity is associated with hepatocellular carcinoma progression., PMID:25199534
For research use only. Not for human or drug use.
