Anti-TFAM Antibody (R3Q12)

Catalog No.

RHF81203

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:20-1:100

Target

Transcription factor 6-like 2, Mitochondrial transcription factor 1, MtTF1, mtTFA, Transcription factor 6, TCF6, TCF6L2, Transcription factor A, mitochondrial, TCF-6, TFAM

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q00059

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3Q12

Ginsenoside Compound K Mitigates Mitochondrial Fission Through Bile Acid Receptors/YAP Signaling to Counteract Podocyte Injury in Lupus Nephritis., PMID:40528637

Anti-TFAM antibodies link mitochondrial damage with antiphospholipid syndrome and thrombosis in SLE., PMID:40350373

Mapping the nanoscale organization of the human cell surface proteome reveals new functional associations and surface antigen clusters., PMID:40027624

Application of Flow Cytometric Analysis for Measuring Multiple Mitochondrial Parameters in 3D Brain Organoids., PMID:37590511

Parkinson's disease neurons exhibit alterations in mitochondrial quality control proteins., PMID:37553379

Oat β-D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis., PMID:37516222

Possible frequent multiple mitochondrial DNA copies in a single nucleoid in HeLa cells., PMID:37031254

Flow Cytometric Analysis of Multiple Mitochondrial Parameters in Human Induced Pluripotent Stem Cells and Their Neural and Glial Derivatives., PMID:34806709

Rescue of thyroid cells from antibody induced cell death via induction of autophagy., PMID:34801870

Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury., PMID:33997750

Proteome Analysis Reveals Distinct Mitochondrial Functions Linked to Interferon Response Patterns in Activated CD4+ and CD8+ T Cells., PMID:31354474

Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392

Sirt1 Promotes a Thermogenic Gene Program in Bone Marrow Adipocytes: From Mice to (Wo)Men., PMID:30873124

Neuroprotective effects of topical coenzyme Q10 + vitamin E in mechanic optic nerve injury model., PMID:30852912

CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth., PMID:30289973

Role of l-carnitine and oleate in myogenic differentiation: implications for myofiber regeneration., PMID:30149425

TFAM is a novel mediator of immunogenic cancer cell death., PMID:29872558

3D super-resolution microscopy reflects mitochondrial cristae alternations and mtDNA nucleoid size and distribution., PMID:29727614

Pattern recognition receptors mediate pro-inflammatory effects of extracellular mitochondrial transcription factor A (TFAM)., PMID:29678518

Prognostic Significance of Mitochondrial Transcription Factor A Expression in Patients with Right- or Left-sided Colorectal Cancer., PMID:29277826

Mitochondrial transcription factor A (TFAM) is upregulated in glioma., PMID:28440425

Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production., PMID:27280778

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus., PMID:27091841

The inflammatory cytokine TWEAK decreases PGC-1α expression and mitochondrial function in acute kidney injury., PMID:26535995

Coupled aggregation of mitochondrial single-strand DNA-binding protein tagged with Eos fluorescent protein visualizes synchronized activity of mitochondrial nucleoids., PMID:26239383

BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension., PMID:25863249

Correlative light and electron microscopic observation of mitochondrial DNA in mammalian cells by using focused-ion beam scanning electron microscopy., PMID:25359841

Increased 8-hydroxy-2'-deoxyguanosine in plasma and decreased mRNA expression of human 8-oxoguanine DNA glycosylase 1, anti-oxidant enzymes, mitochondrial biogenesis-related proteins and glycolytic enzymes in leucocytes in patients with systemic lupus erythematosus., PMID:24345202

Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells., PMID:23172368

Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3β and p53 in response to tumor necrosis factor α., PMID:22911714

Mitochondrial transcription factor A is a proinflammatory mediator in hemorrhagic shock., PMID:22469910

Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA., PMID:21808029

CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation., PMID:18227154

Human mitochondrial DNA nucleoids are linked to protein folding machinery and metabolic enzymes at the mitochondrial inner membrane., PMID:16825194

PDIP38 associates with proteins constituting the mitochondrial DNA nucleoid., PMID:16428295

Human mitochondrial DNA is packaged with TFAM., PMID:12626705

DNA-activated ATPase activity associated with Xenopus transcription factor A., PMID:2943735

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