Catalog No.
RHF71601
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:500-1:1000
Target
Migration inhibitory factor-related protein 6, MRP-6, Extracellular newly identified RAGE-binding protein, p6, Calcium-binding protein in amniotic fluid 1, Calgranulin-C, Protein S100-A12, CGRP, S100 calcium-binding protein A12, Neutrophil S100 protein, CAAF1, EN-RAGE, S100A12, CAGC
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P80511
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3P90
Altered baseline immunological state and impaired immune response to SARS-CoV-2 mRNA vaccination in lung transplant recipients., PMID:40187358
Single-cell RNA sequencing uncovers molecular mechanisms of intravenous immunoglobulin plus methylprednisolone in Kawasaki disease: attenuated monocyte-driven inflammation and improved NK cell cytotoxicity., PMID:39524437
Precision Medicine in Inflammatory Bowel Disease: A Spotlight on Emerging Molecular Biomarkers., PMID:39062093
S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis., PMID:38918871
TLR8 agonist selgantolimod regulates Kupffer cell differentiation status and impairs HBV entry into hepatocytes via an IL-6-dependent mechanism., PMID:38697771
Combination of S100A12/TLR2 signaling molecules and clinical indicators in a new predictive model for IVIG-resistant Kawasaki disease., PMID:38538656
S100A12 is involved in the pathology of osteoarthritis by promoting M1 macrophage polarization via the NF-κB pathway., PMID:38492210
Anti-histone and anti-nucleosome rather than anti-dsDNA antibodies associate with IFN-induced biomarkers in Sudanese and Swedish SLE patients., PMID:38460182
Whole blood RNA sequencing identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis., PMID:38304234
Generation and Application of Monoclonal Antibodies against Porcine S100A8, S100A9, and S100A12 Proteins Using Hybridoma Technology., PMID:38256103
Clinical indicators combined with S100A12/TLR2 signaling molecules to establish a new scoring model for coronary artery lesions in Kawasaki disease., PMID:37824465
Dupilumab effectively and rapidly treats bullous pemphigoid by inhibiting the activities of multiple cell types., PMID:37575240
The potential pathogenic roles of S100A8/A9 and S100A12 in patients with MPO-ANCA-positive vasculitis., PMID:36088289
Intestinal S100/Calgranulin Expression in Cats with Chronic Inflammatory Enteropathy and Intestinal Lymphoma., PMID:36009635
An Immunological Axis Involving Interleukin 1β and Leucine-Rich-α2-Glycoprotein Reflects Therapeutic Response of Children with Kawasaki Disease: Implications from the KAWAKINRA Trial., PMID:35699824
Based on Gene Expression Analysis: Low-Density Neutrophil Expression Is a Characteristic of the Fast Responders Treated With Guselkumab for Psoriasis., PMID:35693833
The potential value of amlexanox in the treatment of cancer: Molecular targets and therapeutic perspectives., PMID:34968491
Patient parameters and response after administration of rituximab in pediatric mature B-cell non-Hodgkin lymphoma., PMID:34939314
Long-Term Elevated Inflammatory Protein Levels in Asymptomatic SARS-CoV-2 Infected Individuals., PMID:34603283
The correlation of serum Vaspin, S100A12 and PCT levels with the severity of ulcerative colitis and its clinical significance., PMID:34377270
Identification of Key Genes and Underlying Mechanisms in Acute Kawasaki Disease Based on Bioinformatics Analysis., PMID:34290221
Studies of mitochondrial and nuclear DNA released from food allergen-activated neutrophils. Implications for non-IgE food allergy., PMID:33980341
Danger-associated molecular pattern molecules and the receptor for advanced glycation end products enhance ANCA-induced responses., PMID:33974049
Association Between Serum Alarmin Levels and Disease-specific Indices in Patients With Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis., PMID:33910860
Kynurenic Acid Analog Attenuates the Production of Tumor Necrosis Factor-α, Calgranulins (S100A 8/9 and S100A 12), and the Secretion of HNP1-3 and Stimulates the Production of Tumor Necrosis Factor-Stimulated Gene-6 in Whole Blood Cultures of Patients With Rheumatoid Arthritis., PMID:33897688
A dysregulated interleukin-18-interferon-γ-CXCL9 axis impacts treatment response to canakinumab in systemic juvenile idiopathic arthritis., PMID:33576397
Antibody microarray analysis of amniotic fluid proteins associated with subsequent ruptured membranes in women with threatened preterm labor., PMID:33155323
Depletion of LAG-3+ T Cells Translated to Pharmacology and Improvement in Psoriasis Disease Activity: A Phase I Randomized Study of mAb GSK2831781., PMID:33113155
Serum proteins may facilitate the identification of Kawasaki disease and promote in vitro neutrophil infiltration., PMID:32973234
Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers., PMID:32849633
Urine and serum S100A8/A9 and S100A12 associate with active lupus nephritis and may predict response to rituximab treatment., PMID:32723832
Identification of Potential Core Genes in Immunoglobulin-Resistant Kawasaki Disease Using Bioinformatics Analysis., PMID:32421987
Unraveling the Role of Receptor for Advanced Glycation End Products (RAGE) and Its Ligands in Myasthenia Gravis., PMID:32017530
Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients., PMID:31156624
GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis., PMID:30738171
The antimicrobial protein S100A12 identified as a potential autoantigen in a subgroup of atopic dermatitis patients., PMID:30728947
S100A12 Serum Levels and PMN Counts Are Elevated in Childhood Systemic Vasculitides Especially Involving Proteinase 3 Specific Anti-neutrophil Cytoplasmic Antibodies., PMID:30533405
Use of biomarkers in inflammatory bowel disease., PMID:30502302
Monocyte-Derived Interleukin-1β As the Driver of S100A12-Induced Sterile Inflammatory Activation of Human Coronary Artery Endothelial Cells: Implications for the Pathogenesis of Kawasaki Disease., PMID:30447136
Long-range PCR libraries and next-generation sequencing for pharmacogenetic studies of patients treated with anti-TNF drugs., PMID:30293984
Clinical utility of currently available biomarkers in inflammatory enteropathies of dogs., PMID:30222209
The localization of CD3, CD79a, CD68 and S100 protein immunoreactive cells in hemal nodes of Saanen goat (Capra hircus)., PMID:30185061
Risk Factors and Biomarkers for the Occurrence of Uveitis in Juvenile Idiopathic Arthritis: Data From the Inception Cohort of Newly Diagnosed Patients With Juvenile Idiopathic Arthritis Study., PMID:29732713
Clinical significance of TM4SF1 as a tumor suppressor gene in gastric cancer., PMID:29665316
Alterations in nucleotide-binding oligomerization domain-2 expression, pathway activation, and cytokine production in Yao syndrome., PMID:29471675
Influence of different sample preparation strategies on the proteomic identification of stress biomarkers in porcine saliva., PMID:29202764
Effect of Adalimumab on Peripheral Blood Mononuclear Cells in Non-Infectious Uveitis., PMID:29020495
Proinflammatory Cytokine Environments Can Drive Interleukin-17 Overexpression by γ/δ T Cells in Systemic Juvenile Idiopathic Arthritis., PMID:28296284
Profile of upregulated inflammatory proteins in sera of Myasthenia Gravis patients., PMID:28045063
Understanding inflammation in juvenile idiopathic arthritis: How immune biomarkers guide clinical strategies in the systemic onset subtype., PMID:27461267
For research use only. Not for human or drug use.
