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Anti-ISL1 Antibody (R3N92)

Catalog #:   RHF42903 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IF, IHC
Accession: P61371
Overview

Catalog No.

RHF42903

Species reactivity

Human, Mouse, Rat, Rabbit

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IF: 1:50-1:500, IHC: 1:100-1:500

Target

Insulin gene enhancer protein ISL-1, ISL1, Islet-1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P61371

Applications

IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3N92

Data Image
  • Immunofluorescence
    Confocal Immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using ISL1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded Mouse brain using ISL1 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded Rat brain using ISL1 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded Rabbit brain using ISL1 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded Rabbit brain using ISL1 mouse mAb with DAB staining.
References

Neuroimaging and immunofluorescence of the Pseudopus apodus brain: unraveling its structural complexity., PMID:40434439

Human breast milk cells are positive for the pioneer transcription factor ISL1., PMID:37782193

IL-6 promotes pluripotency of mouse embryonic stem cells and regulates cardiac differentiation in a development-dependent manner., PMID:36859834

Differential Morphological Diagnosis of Various Forms of Congenital Hyperinsulinism in Children., PMID:34497584

Cochlear hair cells of echolocating bats are immune to intense noise., PMID:34393089

The Atrioventricular Junction: A Potential Niche Region for Progenitor Cells in the Adult Human Heart., PMID:31146637

Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes., PMID:30526659

Insulin gene enhancer binding protein 1 induces adipose tissue‑derived stem cells to differentiate into pacemaker‑like cells., PMID:30483766

Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells., PMID:30281646

ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model., PMID:29482621

Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells., PMID:27672361

Expression of SOX11, PAX5, TTF-1 and ISL-1 in medulloblastoma., PMID:27623204

Neuronal labeling patterns in the spinal cord of adult transgenic Zebrafish., PMID:26408263

A Cranial Mesoderm Origin for Esophagus Striated Muscles., PMID:26387456

Transcription factor ISL1 is essential for pacemaker development and function., PMID:26193633

Intrinsic and extrinsic innervation of the heart in zebrafish (Danio rerio)., PMID:25711945

Bone marrow minimal residual disease was an early response marker and a consistent independent predictor of survival after anti-GD2 immunotherapy., PMID:25559819

Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network., PMID:25468937

'Neuroendocrine' middle ear adenomas: consistent expression of the transcription factor ISL1 further supports their neuroendocrine derivation., PMID:24766278

Islet1 and its co-factor Ldb1 are expressed in quiescent cells of mouse intestinal epithelium., PMID:24755910

Pulmonary endoderm, second heart field and the morphogenesis of distal outflow tract in mouse embryonic heart., PMID:24697670

Islet-1 overexpression in human mesenchymal stem cells promotes vascularization through monocyte chemoattractant protein-3., PMID:24578274

Transcription profiles of endothelial cells in the rat ductus arteriosus during a perinatal period., PMID:24086288

Expression of Isl1 during mouse development., PMID:23906961

Identification and biological characterization of chicken embryonic cardiac progenitor cells., PMID:23510478

Second heart field and the development of the outflow tract in human embryonic heart., PMID:23488909

Haemogenic endocardium contributes to transient definitive haematopoiesis., PMID:23463007

α2-Macroglobulin enhances vasculogenesis/angiogenesis of mouse embryonic stem cells by stimulation of nitric oxide generation and induction of fibroblast growth factor-2 expression., PMID:23379699

Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genes., PMID:23269676

Heterogeneity of intrinsically photosensitive retinal ganglion cells in the mouse revealed by molecular phenotyping., PMID:22886938

Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification., PMID:22833130

Developmental programming of neonatal pancreatic β-cells by a maternal low-protein diet in rats involves a switch from proliferation to differentiation., PMID:22436693

Hormonally defined pancreatic and duodenal neuroendocrine tumors differ in their transcription factor signatures: expression of ISL1, PDX1, NGN3, and CDX2., PMID:21739268

Genetic modulation of horizontal cell number in the mouse retina., PMID:21576457

Insulin-like growth factor 2 enhances insulinogenic differentiation of human eyelid adipose stem cells via the insulin receptor., PMID:21535266

POU homeodomain protein OCT1 modulates islet 1 expression during cardiac differentiation of P19CL6 cells., PMID:20960024

Neuronal restrictive silencing factor silencing induces human amniotic fluid-derived stem cells differentiation into insulin-producing cells., PMID:20942606

SOX2 is required for adult human muller stem cell survival and maintenance of progenicity in vitro., PMID:20739473

Characterization of mouse embryonic stem cell differentiation into the pancreatic lineage in vitro by transcriptional profiling, quantitative RT-PCR and immunocytochemistry., PMID:19876843

FHL1 interacts with oestrogen receptors and regulates breast cancer cell growth., PMID:19840196

Human bone marrow mesenchymal stem cells differentiate into insulin-producing cells upon microenvironmental manipulation in vitro., PMID:19505629

Spatio-temporal expression of Pax6 in Xenopus forebrain., PMID:18786519

Mesenchymal stem cells derived from human exocrine pancreas express transcription factors implicated in beta-cell development., PMID:18580448

Islet1 as a marker of subdivisions and cell types in the developing forebrain of Xenopus., PMID:18515014

Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2., PMID:18460603

Cardiac stem cells in the real world., PMID:18329492

Islet 1 (Isl1) expression is a reliable marker for pancreatic endocrine tumors and their metastases., PMID:18300808

Pancreatic endocrine and exocrine cell ontogeny from renal capsule transplanted embryonic stem cells in streptozocin-injured mice., PMID:17875656

Differentiation in vivo of cardiac committed human embryonic stem cells in postmyocardial infarcted rats., PMID:17540853

Early identification of retinal subtypes in the developing, pre-laminated chick retina using the transcription factors Prox1, Lim1, Ap2alpha, Pax6, Isl1, Isl2, Lim3 and Chx10., PMID:16864127

Datasheet

Document Download

Anti-ISL1 Antibody (R3N92).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-ISL1 Antibody (R3N92) [RHF42903]
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