Catalog No.
RHF40603
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Actin-like protein 3, Actin-related protein 3, ACTR3, ARP3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P61158
Applications
ELISA, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3N88
Dendrobium huoshanense polysaccharide inhibits NSCLC proliferation and immune evasion via FXR1-IL-35 axis signaling pathway., PMID:40259042
Nuclear interaction of Arp2/3 complex and BRAFV600E promotes aggressive behavior and vemurafenib resistance of thyroid cancer., PMID:35968344
BSG/CD147 and ACE2 receptors facilitate SARS-CoV-2 infection of human iPS cell-derived kidney podocytes., PMID:34816259
A panel of autoantibodies against tumor-associated antigens in the early immunodiagnosis of lung cancer., PMID:31980218
Discovering novel lung cancer associated antigens and the utilization of their autoantibodies in detection of lung cancer., PMID:31839396
Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation., PMID:31157616
ox-LDL induces endothelial dysfunction by promoting Arp2/3 complex expression., PMID:27181356
MRP-1/CD9 gene transduction regulates the actin cytoskeleton through the downregulation of WAVE2., PMID:16682943
Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility., PMID:16027158
Involvement of Arp2/3 complex in MCP-1-induced chemotaxis., PMID:16004967
Activated cofilin colocalises with Arp2/3 complex in apoptotic blebs during programmed cell death., PMID:15900709
Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement., PMID:15741236
Actin-related protein 2/3 complex is required for actin ring formation., PMID:15040839
Beta 3 integrin phosphorylation is essential for Arp3 organization into leukocyte alpha V beta 3-vitronectin adhesion contacts., PMID:14996908
RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery., PMID:14742709
Role for phosphoinositide 3-kinase in Fc gamma RIIA-induced platelet shape change., PMID:12788695
Actin-based motility of Burkholderia pseudomallei involves the Arp 2/3 complex, but not N-WASP and Ena/VASP proteins., PMID:12780776
Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP., PMID:12769847
A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton., PMID:12672817
Identification and characterisation of a novel human isoform of Arp2/3 complex subunit p16-ARC/ARPC5., PMID:12451597
Syndapins integrate N-WASP in receptor-mediated endocytosis., PMID:12426380
Arp2/3 complex is required for actin polymerization during platelet shape change., PMID:12036877
Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells., PMID:11706047
Yersinia enterocolitica invasin triggers phagocytosis via beta1 integrins, CDC42Hs and WASp in macrophages., PMID:11580754
CD2AP and p130Cas localize to different F-actin structures in podocytes., PMID:11553524
ActA and human zyxin harbour Arp2/3-independent actin-polymerization activity., PMID:11483954
The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension., PMID:11369208
WIP regulates N-WASP-mediated actin polymerization and filopodium formation., PMID:11331876
Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex., PMID:10995437
The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex., PMID:10861055