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Anti-EPHB3 Antibody (R3N26)

Catalog #:   RHF04902 Specific References (27) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: IHC
Accession: P54753
Overview

Catalog No.

RHF04902

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

IHC: 1:200-1:1000

Target

EPHB3, Embryonic kinase 2, EPH-like tyrosine kinase 2, Tyrosine-protein kinase TYRO6, EPH-like kinase 2, ETK2, EK2, hEK2, HEK2, Ephrin type-B receptor 3, TYRO6

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P54753

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3N26

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human lung squamous cell carcinoma (A), lung adenocarcinoma (B), colon carcinoma (C), breast carcinoma (D), normal sublingual gland (E), normal rectal (F), showing membrane localization with DAB staining using EphB3 mouse mAb.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human Adrenal tissues using EPHB3 mouse mAb
References

Eph Receptor Tyrosine Kinases Are Functional Entry Receptors for Murine Gammaherpesvirus 68., PMID:40501621

Peripheral T-cell responses of EphB2- and EphB3-deficient mice in a model of collagen-induced arthritis., PMID:38558087

EphB3 protein is a potential ancillary diagnostic biomarker for thyroid cancers., PMID:38150866

Sonic hedgehog pathway activation is associated with cetuximab resistance and EPHB3 receptor induction in colorectal cancer., PMID:31149041

Altered Maturation of Medullary TEC in EphB-Deficient Thymi Is Recovered by RANK Signaling Stimulation., PMID:29867988

EphB3 protein is associated with histological grade and FIGO stage in ovarian serous carcinomas., PMID:28120491

Eph/ephrin-B-mediated cell-to-cell interactions govern MTS20(+) thymic epithelial cell development., PMID:27060907

Optimizing antibody expression by using the naturally occurring framework diversity in a live bacterial antibody display system., PMID:26631978

TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer., PMID:24178904

Prolactin-induced protein (PIP) regulates proliferation of luminal A type breast cancer cells in an estrogen-independent manner., PMID:23755096

5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: role of the ERK pathway., PMID:23380172

EphB regulates L1 phosphorylation during retinocollicular mapping., PMID:22579729

Involvement of EphB/Ephrin-B signaling in axonal survival in mouse experimental glaucoma., PMID:22064993

Complementary expression and repulsive signaling suggest that EphB receptors and ephrin-B ligands control cell positioning in the gastric epithelium., PMID:21959989

Complementary expression of EphB receptors and ephrin-B ligand in the pyloric and duodenal epithelium of adult mice., PMID:21818578

Epithelial dynamics of pancreatic branching morphogenesis., PMID:21098570

Ephrin-B reverse signaling is required for formation of strictly contralateral auditory brainstem pathways., PMID:20660266

Developmental expression of Eph and ephrin family genes in mammalian small intestine., PMID:20112066

Distribution of EphB receptors and ephrin-B1 in the developing vertebrate spinal cord., PMID:16786562

GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking., PMID:15965473

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases., PMID:15536074

Expression of ephrinB2 and its receptors on fibroproliferative membranes in ocular angiogenic diseases., PMID:15289137

Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development., PMID:15223334

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus., PMID:14691139

Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectin., PMID:12907451

Induction of cellular genes is mediated by the Bel1 transactivator in foamy virus-infected human cells., PMID:10775579

Spinal motor axons and neural crest cells use different molecular guides for segmental migration through the rostral half-somite., PMID:10699981

Datasheet

Document Download

Anti-EPHB3 Antibody (R3N26).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-EPHB3 Antibody (R3N26) [RHF04902]
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