Catalog No.
RHE93203
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
EG5, TR-interacting protein 5, Kinesin-like protein KIF11, TRIP-5, KNSL1, Kinesin-like spindle protein HKSP, TRIP5, Kinesin-related motor protein Eg5, Thyroid receptor-interacting protein 5, KIF11, Kinesin-like protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P52732
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3M89
Integrative analysis of serum proteomics and transcriptomics in hepatitis C., PMID:40082995
FANCI is Associated with Poor Prognosis and Immune Infiltration in Liver Hepatocellular Carcinoma., PMID:37324186
Investigation of the mechanisms and experimental verification of Shao yao gan cao decoction against Sphincter of Oddi Dysfunction via systems pharmacology., PMID:36654051
Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy., PMID:35608632
Comparative Analysis on Abnormal Methylome of Differentially Expressed Genes and Disease Pathways in the Immune Cells of RA and SLE., PMID:34079550
Tailored Linker Chemistries for the Efficient and Selective Activation of ADCs with KSPi Payloads., PMID:32667786
Filanesib for the treatment of multiple myeloma., PMID:31815551
Antibody-Drug Conjugates with Pyrrole-Based KSP Inhibitors as the Payload Class., PMID:30180286
Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer., PMID:29115586
AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients., PMID:28101582
Mitotic motors coregulate microtubule patterns in axons and dendrites., PMID:23035110
A phase 1 dose-escalation study of ARRY-520, a kinesin spindle protein inhibitor, in patients with advanced myeloid leukemias., PMID:22139909
Inhibition of Kinesin-5, a microtubule-based motor protein, as a strategy for enhancing regeneration of adult axons., PMID:21166743
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry., PMID:20386726
Anti-NuMA antibodies in a psoriatic patient: considerations about clinical relevance and effect of infliximab treatment., PMID:19951065
Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells., PMID:19931454
Truncated form of tenascin-X, XB-S, interacts with mitotic motor kinesin Eg5., PMID:18679583
Disruption of the mitotic kinesin Eg5 gene (Knsl1) results in early embryonic lethality., PMID:18474226
Cytomegalovirus destruction of focal adhesions revealed in a high-throughput Western blot analysis of cellular protein expression., PMID:17522202
MKLP1 requires specific domains for its dendritic targeting., PMID:16418225
Centrioles resist forces applied on centrosomes during G2/M transition., PMID:15898952
Congenital heart block associated with a maternal anti-HsEg5-like autoantibody., PMID:15695294
XMAP215, XKCM1, NuMA, and cytoplasmic dynein are required for the assembly and organization of the transient microtubule array during the maturation of Xenopus oocytes., PMID:14499655
A novel action of terpendole E on the motor activity of mitotic Kinesin Eg5., PMID:12618185
Involvement of Aurora A kinase during meiosis I-II transition in Xenopus oocytes., PMID:12426316
[Clinical significance of fluoroscopic patterns specific for the mitotic spindle in patients with rheumatic diseases]., PMID:12404031
Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport., PMID:12235119
The microtubule-destabilizing kinesin XKCM1 regulates microtubule dynamic instability in cells., PMID:12181341
The Xenopus laevis aurora/Ip11p-related kinase pEg2 participates in the stability of the bipolar mitotic spindle., PMID:10912796
Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts., PMID:10620801
The kinesin-related protein, HSET, opposes the activity of Eg5 and cross-links microtubules in the mammalian mitotic spindle., PMID:10525540
Cell cycle analysis and synchronization of the Xenopus laevis XL2 cell line: study of the kinesin related protein XlEg5., PMID:10206152
Expression of the mitotic motor protein Eg5 in postmitotic neurons: implications for neuronal development., PMID:9742151
Expanding the role of HsEg5 within the mitotic and post-mitotic phases of the cell cycle., PMID:9701554
Dynamic changes in nuclear architecture during mitosis: on the role of protein phosphorylation in spindle assembly and chromosome segregation., PMID:8986594
Opposing motor activities are required for the organization of the mammalian mitotic spindle pole., PMID:8896597
Two major autoantigen-antibody systems of the mitotic spindle apparatus., PMID:8843854
The spindle kinesin-like protein HsEg5 is an autoantigen in systemic lupus erythematosus., PMID:8843853
XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly., PMID:8548824
The relationship of HsEg5 and the actin cytoskeleton to centrosome separation., PMID:8956002
Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo., PMID:8548803
The kinesin-related protein Eg5 associates with both interphase and spindle microtubules during Xenopus early development., PMID:8026619
For research use only. Not for human or drug use.
