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Anti-GPR15 Antibody (R3L92)

Catalog #:   RHE68101 Specific References (21) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: ELISA, FCM, IF
Accession: P49685
Overview

Catalog No.

RHE68101

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000

Target

Brother of Bonzo, GPR15, G-protein coupled receptor 15, BoB

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P49685

Applications

ELISA, FCM, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3L92

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Raji cells using GPR15 mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of Jurkat cells using GPR15 mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of THP-1 cells using GPR15 mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using GPR15 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
References

Blocking GPR15 Counteracts Integrin-dependent T Cell Gut Homing in Vivo., PMID:38243565

HIV-2 Neutralization Sensitivity in Relation to Co-Receptor Entry Pathways and Env Motifs., PMID:35563157

To Go or Not to Go?-Targeting Tregs Traveling in Tumors., PMID:34087782

Immune changes beyond Th2 pathways during rapid multifood immunotherapy enabled with omalizumab., PMID:33782956

The G Protein-Coupled Receptor (GPR) 15 Counteracts Antibody-Mediated Skin Inflammation., PMID:32922401

Functional study of acetaldehyde dehydrogenase 1 (ALDH1) in keratinocytes: microarray integrating bioinformatics approaches., PMID:32189581

GPR15 is not critically involved in the regulation of murine psoriasiform dermatitis., PMID:30935778

Leukocyte Trafficking to the Small Intestine and Colon., PMID:26551552

Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo., PMID:26209553

Orphan receptor GPR15/BOB is up-regulated in rheumatoid arthritis., PMID:24725539

Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques., PMID:23325697

Evolution of coreceptor use and CD4-independence in envelope clones derived from SIVsm-infected macaques., PMID:14599787

Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS., PMID:14581570

The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C., PMID:12634405

The virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal cell line., PMID:12566994

Gp120-induced Bob/GPR15 activation: a possible cause of human immunodeficiency virus enteropathy., PMID:11696454

Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia., PMID:11115360

Simian immunodeficiency viruses of diverse origin can use CXCR4 as a coreceptor for entry into human cells., PMID:10823878

Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates., PMID:9847323

Neutralizing antibodies in sera from macaques immunized with attenuated simian immunodeficiency virus., PMID:9658152

CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain., PMID:9405683

Datasheet

Document Download

Anti-GPR15 Antibody (R3L92).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-GPR15 Antibody (R3L92) [RHE68101]
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