Catalog No.
RHE68101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000
Target
Brother of Bonzo, GPR15, G-protein coupled receptor 15, BoB
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P49685
Applications
ELISA, FCM, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3L92
Blocking GPR15 Counteracts Integrin-dependent T Cell Gut Homing in Vivo., PMID:38243565
HIV-2 Neutralization Sensitivity in Relation to Co-Receptor Entry Pathways and Env Motifs., PMID:35563157
To Go or Not to Go?-Targeting Tregs Traveling in Tumors., PMID:34087782
Immune changes beyond Th2 pathways during rapid multifood immunotherapy enabled with omalizumab., PMID:33782956
The G Protein-Coupled Receptor (GPR) 15 Counteracts Antibody-Mediated Skin Inflammation., PMID:32922401
Functional study of acetaldehyde dehydrogenase 1 (ALDH1) in keratinocytes: microarray integrating bioinformatics approaches., PMID:32189581
GPR15 is not critically involved in the regulation of murine psoriasiform dermatitis., PMID:30935778
Leukocyte Trafficking to the Small Intestine and Colon., PMID:26551552
Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo., PMID:26209553
Orphan receptor GPR15/BOB is up-regulated in rheumatoid arthritis., PMID:24725539
Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques., PMID:23325697
Evolution of coreceptor use and CD4-independence in envelope clones derived from SIVsm-infected macaques., PMID:14599787
Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS., PMID:14581570
The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C., PMID:12634405
The virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal cell line., PMID:12566994
Gp120-induced Bob/GPR15 activation: a possible cause of human immunodeficiency virus enteropathy., PMID:11696454
Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia., PMID:11115360
Simian immunodeficiency viruses of diverse origin can use CXCR4 as a coreceptor for entry into human cells., PMID:10823878
Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates., PMID:9847323
Neutralizing antibodies in sera from macaques immunized with attenuated simian immunodeficiency virus., PMID:9658152
CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain., PMID:9405683