Catalog No.
RHE61902
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000
Target
ADGRE5, Adhesion G protein-coupled receptor E5, Leukocyte antigen CD97, CD97
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P48960
Applications
ELISA, FCM, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3L83
CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells., PMID:39637858
Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1., PMID:38758649
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides., PMID:38053024
Dynamic encounters with red blood cells trigger splenic marginal zone B cell retention and function., PMID:38049580
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability., PMID:37938973
Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer., PMID:37272843
Targeting pediatric leukemia-propagating cells with anti-CD200 antibody therapy., PMID:34470052
Author Correction: G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody., PMID:32184438
G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody., PMID:31969668
Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment., PMID:29164976
Detection of minimal residual disease in childhood B-acute lymphoblastic leukemia by 4-color flowcytometry., PMID:28324281
Membrane proteome analysis of glioblastoma cell invasion., PMID:25853691
Expression of B-cell-associated genes in peripheral blood mononuclear cells of patients with symptomatic pulmonary embolism., PMID:25411767
Triggering of the dsRNA sensors TLR3, MDA5, and RIG-I induces CD55 expression in synovial fibroblasts., PMID:22590509
F4/80 and the related adhesion-GPCRs., PMID:21952799
[Human CD96 gene cloning, expression and identification]., PMID:21764703
The cell surface proteome of human mesenchymal stromal cells., PMID:21637820
CD97 antibody depletes granulocytes in mice under conditions of acute inflammation via a Fc receptor-dependent mechanism., PMID:21169517
Oncoproteomic analysis reveals co-upregulation of RELA and STAT5 in carboplatin resistant ovarian carcinoma., PMID:20585448
Role of CD97 isoforms in gastric carcinoma., PMID:20428763
Decay-accelerating factor 1 (Daf1) deficiency exacerbates xenobiotic-induced autoimmunity., PMID:20408894
Deletion of either CD55 or CD97 ameliorates arthritis in mouse models., PMID:20131275
CD97 in leukocyte trafficking., PMID:21618832
Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2., PMID:19717518
Differential expression of CD97 on human lymphocyte subsets and limited effect of CD97 antibodies on allogeneic T-cell stimulation., PMID:19428565
Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration., PMID:18941248
Differential role of CD97 in interleukin-8-induced and granulocyte-colony stimulating factor-induced hematopoietic stem and progenitor cell mobilization., PMID:18326527
CD97 neutralisation increases resistance to collagen-induced arthritis in mice., PMID:17007638
Costimulation via CD55 on human CD4+ T cells mediated by CD97., PMID:16818763
Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies., PMID:16784816
Rapid leukocyte activation following intraarticular bleeding., PMID:16514634
Diversity of CD97 in smooth muscle cells., PMID:16408199
Dedicated pinhole SPECT of intestinal neutrophil recruitment in a mouse model of dextran sulfate sodium-induced colitis., PMID:15750169
Intact-protein-based high-resolution three-dimensional quantitative analysis system for proteome profiling of biological fluids., PMID:15703445
Identification of the epidermal growth factor-TM7 receptor EMR2 and its ligand dermatan sulfate in rheumatoid synovial tissue., PMID:15693006
Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells., PMID:15498814
N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding., PMID:15386373
The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense., PMID:14707087
The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans., PMID:12829604
Enhanced expression of the complement regulatory protein CD55 predicts a poor prognosis in colorectal cancer patients., PMID:12811528
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells., PMID:11994511
CD97-decay-accelerating factor interaction is not involved in leukocyte adhesion to endothelial cells., PMID:11884941
Tissue distribution of the human CD97 EGF-TM7 receptor., PMID:11380941
Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans., PMID:11157498
Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97., PMID:10903844
Molecular cloning and characterization of mouse CD97., PMID:10744645
Decay accelerating factor (CD55): a target for cancer vaccines?, PMID:10344729
Expression of the activation antigen CD97 and its ligand CD55 in rheumatoid synovial tissue., PMID:10211878
Activation of peripheral blood T cells by interaction and migration through endothelium: role of lymphocyte function antigen-1/intercellular adhesion molecule-1 and interleukin-15., PMID:9920837
Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies., PMID:9764855
For research use only. Not for human or drug use.
