Catalog No.
RHE55201
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000
Target
PINCH, Renal carcinoma antigen NY-REN-48, PINCH1, LIM and senescent cell antigen-like-containing domain protein 1, LIMS1, PINCH-1, Particularly interesting new Cys-His protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P48059
Applications
ELISA, FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3L69
Genomic collision at the LIMS-1 locus increases risk of cellular mediated allograft rejection in heart transplanted recipients., PMID:39642779
Coexistence of systemic sclerosis and cryopyrin-associated periodic syndrome., PMID:38940218
Circulating Autoantibody Profiling Identifies LIMS1 as a Potential Target for Pathogenic Autoimmunity in pathologic Myopia., PMID:38729610
LIMS1 risk genotype and T cell-mediated rejection in kidney transplant recipients., PMID:33909908
Genetic background and transplantation outcomes: insights from genome-wide association studies., PMID:31815792
Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection., PMID:31091373
ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation., PMID:26460618
Targeting of the EGFR/β1 integrin connecting proteins PINCH1 and Nck2 radiosensitizes three-dimensional SCC cell cultures., PMID:26004008
A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods., PMID:25820723
Galectin 9 and PINCH, novel immunotherapy targets of renal cell carcinoma: a rationale to find potential tumour antigens and the resulting cytotoxic T lymphocytes induced by the derived peptides., PMID:24895689
Caveolin-1 and integrin β1 regulate embryonic stem cell proliferation via p38 MAPK and FAK in high glucose., PMID:21506116
Neuronal PINCH is regulated by TNF-α and is required for neurite extension., PMID:20689998
Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase., PMID:19117955
Novel expression of PINCH in the central nervous system and its potential as a biomarker for human immunodeficiency virus-associated neurodegeneration., PMID:18459134
Signalling via integrins: implications for cell survival and anticancer strategies., PMID:17084981
PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage., PMID:15976450
Stromal staining for PINCH is an independent prognostic indicator in colorectal cancer., PMID:15720806
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites., PMID:12432066
The signaling adapter protein PINCH is up-regulated in the stroma of common cancers, notably at invasive edges., PMID:12216108
Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration., PMID:12167643
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading., PMID:11331308
Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumors., PMID:11313893
Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways., PMID:9843575
For research use only. Not for human or drug use.
