A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning., PMID:38760690
Lenvatinib improves anti-PD-1 therapeutic efficacy by promoting vascular normalization via the NRP-1-PDGFRβ complex in hepatocellular carcinoma., PMID:37545530
CRKL, AIFM3, AIF, BCL2, and UBASH3A during Human Kidney Development., PMID:34502088
Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction., PMID:34417497
Central 22q11.2 deletion (LCR22 B-D) in a fetus with severe fetal growth restriction and a mother with severe systemic lupus erythematosus: Further evidence of CRKL haploinsufficiency in the pathogenesis of 22q11.2 deletion syndrome., PMID:34196458
Downregulated miR‑29a promotes B cell overactivation by upregulating Crk‑like protein in systemic lupus erythematosus., PMID:32467986
Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients., PMID:29348127
Reduction of CRKL expression in patients with partial DiGeorge syndrome is associated with impairment of T-cell functions., PMID:26875746
Antibody-based detection of protein phosphorylation status to track the efficacy of novel therapies using nanogram protein quantities from stem cells and cell lines., PMID:25521791
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector., PMID:25482634
CrkL regulates SDF-1-induced breast cancer biology through balancing Erk1/2 and PI3K/Akt pathways., PMID:25476480
A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis., PMID:24886428
Nucleolin promotes TGF-β signaling initiation via TGF-β receptor I in glioblastoma., PMID:24682943
CRKL promotes lung cancer cell invasion through ERK-MMP9 pathway., PMID:24664993
Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL., PMID:23770091
Src-inducible association of CrkL with procaspase-8 promotes cell migration., PMID:23751956
The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria., PMID:22448228
Proteomic studies of Syk-interacting proteins using a novel amine-specific isotope tag and GFP nanotrap., PMID:21472591
Protein tyrosine phosphatase receptor type {gamma} is a functional tumor suppressor gene specifically downregulated in chronic myeloid leukemia., PMID:20959494
NGF/TrkA-mediated Kidins220/ARMS signaling activated in the allergic airway challenge in mice., PMID:20934630
TOB suppresses breast cancer tumorigenesis., PMID:19569230
Monitoring cell signaling pathways by quantitative flow cytometry., PMID:18605080
Capture of an activated receptor complex from the surface of live cells by affinity receptor chromatography., PMID:18601892
Subcellular distribution of p210(BCR-ABL) in CML cell lines and primary CD34+ CML cells., PMID:18059481
IgEb immune complexes activate macrophages through FcgammaRIV binding., PMID:17558411
Impaired Crkl expression contributes to the defective DNA binding of Stat5b in nonobese diabetic mice., PMID:16505237
PECAM-1 isoform-specific activation of MAPK/ERKs and small GTPases: implications in inflammation and angiogenesis., PMID:16440301
Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes., PMID:16399079
Imatinib mesylate (STI571) abrogates the resistance to doxorubicin in human K562 chronic myeloid leukemia cells by inhibition of BCR/ABL kinase-mediated DNA repair., PMID:16388976
Smenospongine, a spongean sesquiterpene aminoquinone, induces erythroid differentiation in K562 cells., PMID:15057141
T cell development and function in CrkL-deficient mice., PMID:14515252
Activation of Rac and tyrosine phosphorylation of cytokine receptors induced by cross-linking of integrin alpha4beta1 and cell adhesion in hematopoietic cells., PMID:12589802
Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion., PMID:11809811
Differential interaction of Cbl with Grb2 and CrkL in CD2-mediated NK cell activation., PMID:11399323
The adapter protein CrkL associates with CD34., PMID:11389015
The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation., PMID:11133830
Cell-penetrating SH3 domain blocker peptides inhibit proliferation of primary blast cells from CML patients., PMID:10928987
Engagement of the CrkL adapter in interleukin-5 signaling in eosinophils., PMID:10926930
All-trans-retinoic acid induces tyrosine phosphorylation of the CrkL adapter in acute promyelocytic leukemia cells., PMID:10907644
CrkL functions as a nuclear adaptor and transcriptional activator in Bcr-Abl-expressing cells., PMID:10720695
Role of Src in the modulation of multiple adaptor proteins in FcalphaRI oxidant signaling., PMID:10477741
Role of protein kinase C in signal attenuation following T cell receptor engagement., PMID:10400642
Involvement of the adapter protein CRKL in integrin-mediated adhesion., PMID:10362355
CrkL activates integrin-mediated hematopoietic cell adhesion through the guanine nucleotide exchange factor C3G., PMID:10339478
Physiological signals and oncogenesis mediated through Crk family adapter proteins., PMID:10092207
BCR-ABL oncoprotein is expressed by platelets from CML patients and associated with a special pattern of CrkL phosphorylation., PMID:9886328
Thrombopoietin induces association of Crkl with STAT5 but not STAT3 in human platelets., PMID:9845531
Association of CrkL with STAT5 in hematopoietic cells stimulated by granulocyte-macrophage colony-stimulating factor or erythropoietin., PMID:9837784
Adaptor proteins in lymphocyte antigen-receptor signaling., PMID:9638371
Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells., PMID:9498705
For research use only. Not for human or drug use.
