Catalog No.
RHE44606
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200
Target
Thyroid-specific enhancer-binding protein, Homeobox protein NK-2 homolog A, TTF1, Homeobox protein Nkx-2.1, NKX2-1, TITF1, Thyroid transcription factor 1, NKX2A, Thyroid nuclear factor 1, T/EBP, TTF-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P43699
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3L29
Lung adenocarcinomas with mucinous histology: clinical, genomic, and immune microenvironment characterization and outcomes to immunotherapy-based treatments and KRASG12C inhibitors., PMID:39637943
TTF-1 is a highly sensitive but not fully specific marker for pulmonary and thyroidal cancer: a tissue microarray study evaluating more than 17,000 tumors from 152 different tumor entities., PMID:39377914
Non-small cell lung carcinoma with focal coexpression of thyroid transcription factor-1 and Δ Np63/p40: A case report., PMID:38478955
Interneuron Origins in the Embryonic Porcine Medial Ganglionic Eminence., PMID:33637558
TTF-1 and c-MYC-defined Phenotypes of Large Cell Neuroendocrine Carcinoma and Delta-like Protein 3 Expression for Treatment Selection., PMID:33031101
Derivation and 97% Purification of Human Thyroid Cells From Dermal Fibroblasts., PMID:32760346
Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice., PMID:32375878
The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components., PMID:31988094
TTF-1 Positivity in Merkel Cell Carcinoma: The Chosen Clone Matters., PMID:31917690
Poorly differentiated neuroendocrine rectal carcinoma with uncommon immune-histochemical features and clinical presentation with a subcutaneous metastasis, treated with first line intensive triplet chemotherapy plus bevacizumab FIr-B/FOx regimen: an experience of multidisciplinary management in clinical practice., PMID:31619203
The Incidence of Labelling of Non-Lung Adenocarcinomas With Antibodies Against TTF-1 and Diagnostic Implications., PMID:31135446
TTF-1 Expression Predicts the Merit of Additional Antiangiogenic Treatment in Non-squamous Non-small Cell Lung Cancer., PMID:30194207
Clinicopathological and molecular implications of aberrant thyroid transcription factor-1 expression in colorectal carcinomas: an immunohistochemical analysis of 1319 cases using three different antibody clones., PMID:28914964
Rapid Immunohistochemistry With Thyroid Transcription Factor-1 for Pulmonary Adenocarcinoma., PMID:28527968
Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters., PMID:28281552
An Adult Mouse Thyroid Side Population Cell Line that Exhibits Enriched Epithelial-Mesenchymal Transition., PMID:28125936
HURTLE CELLS IMMUNOHISTOCHEMICAL ACTIVITIES IN HASHIMOTO THYROIDITIS PARENCHYMA., PMID:28009314
Various Antibody Clones of Napsin A, Thyroid Transcription Factor 1, and p40 and Comparisons With Cytokeratin 5 and p63 in Histopathologic Diagnostics of Non-Small Cell Lung Carcinoma., PMID:26447895
Immunoprofiling of glial tumours of the neurohypophysis suggests a common pituicytic origin of neoplastic cells., PMID:27744503
Computed Tomographic and Pathological Features of Primary Pulmonary Sarcomatoid Carcinoma., PMID:26956864
Thyroid Transcription Factor 1 Reprograms Angiogenic Activities of Secretome., PMID:26912193
Cell Growth Dynamics in Embryonic and Adult Mouse Thyroid Revealed by a Novel Approach to Detect Thyroid Gland Subpopulations., PMID:26854713
Expressions of Thyroid Transcription Factor-1, Napsin A, p40, p63, CK5/6 and Desmocollin-3 in Non-Small Cell Lung Cancer, as Revealed by Imprint Cytology Using a Malinol-Based Cell-Transfer Technique., PMID:26696549
Unexpected TTF-1 Positivity in a Subset of Gastric Adenocarcinomas., PMID:26469324
Intrathecal Transplantation of Embryonic Stem Cell-Derived Spinal GABAergic Neural Precursor Cells Attenuates Neuropathic Pain in a Spinal Cord Injury Rat Model., PMID:26407027
Diagnostic significance of PAX8 in thyroid squamous cell carcinoma., PMID:26354716
An immunohistochemical comparison of two TTF-1 monoclonal antibodies in atypical squamous lesions and sarcomatoid carcinoma of the lung, and pleural malignant mesothelioma., PMID:26281863
Napsin A is frequently expressed in clear cell carcinoma of the ovary and endometrium., PMID:25971546
Reevaluation and reclassification of resected lung carcinomas originally diagnosed as squamous cell carcinoma using immunohistochemical analysis., PMID:25871623
Development and regression of the thyroglossal duct in mice., PMID:25771082
DYRK1A BAC transgenic mouse: a new model of thyroid dysgenesis in Down syndrome., PMID:25490145
Different cutoff values for thyroid transcription factor-1 antibodies in the diagnosis of lung adenocarcinoma., PMID:25356948
The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling., PMID:25169055
Diagnosis of lymph node micrometastasis at the pN₀ stage of lung adenocarcinoma using a combination of markers., PMID:25117316
Antigenic phenotype of lung carcinomas: usual spectrum of distribution of thyroid transcription factor-1, cytokeratin 7, cytokeratin 20, and neuron specific enolase--basic immunohistochemical study of 21 cases., PMID:24798606
Unusual expression of thyroid transcription factor 1 and napsin A in metastatic adenoid cystic carcinoma of extrapulmonary origin in the lung., PMID:24713744
Napsin-A, TTF-1, EGFR, and ALK Status Determination in Lung Primary and Metastatic Mucin-Producing Adenocarcinomas., PMID:24651909
TTF-1 and Napsin-A are expressed in a subset of cholangiocarcinomas arising from the gallbladder and hepatic ducts: continued caveats for utilization of immunohistochemistry panels., PMID:24418856
Stem cell antigen 1-positive mesenchymal cells are the origin of follicular cells during thyroid regeneration., PMID:24278321
Paired diagnostic and pharmacodynamic analysis of rare non-small cell lung cancer cells enabled by the VerIFAST platform., PMID:24158597
TTF-1 expression in breast carcinoma: an unusual but real phenomenon., PMID:24111789
Update on hypophysitis and TTF-1 expressing sellar region masses., PMID:23701182
Preparation of thyroid follicular cells for mRNA quantification after fluorescence-activated cell sorting., PMID:23544456
Significant expression of thyroid transcription factor-1 in pulmonary squamous cell carcinoma detected by SPT24 monoclonal antibody and CSA-II system., PMID:23531851
Tissue-preserving antibody cocktails to differentiate primary squamous cell carcinoma, adenocarcinoma, and small cell carcinoma of lung., PMID:23289761
Thyroid transcription factor 1 and Napsin A double stain: utilizing different vendor antibodies for diagnosing lung adenocarcinoma., PMID:23207437
Nuclear receptor COUP-TFII-expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons., PMID:22791192
Value of thyroid transcription factor-1 immunostaining in tumor diagnosis: a review and update., PMID:22531688
Thyroid transcription factor-1 is not expressed in squamous cell carcinomas of the lung: an immunohistochemical study with review of the literature., PMID:22531686
Carcinoma of unknown primary: check the liver... thanks to TTF-1., PMID:22359993
For research use only. Not for human or drug use.
