Catalog No.
RHE43703
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
HLA-BW4-specific inhibitory NK cell receptor, NKB1, KIR3DL1, p70 NK receptor CL-2/CL-11, CD158E, MHC class I NK cell receptor, Killer cell immunoglobulin-like receptor 3DL1, p70 natural killer cell receptor clones CL-2/CL-11, Natural killer-associated transcript 3, NKAT-3, CD158e, CD158 antigen-like family member E, NKAT3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P43629
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3L24
Immunomonitoring of Stage IV Relapsed Neuroblastoma Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation and Subsequent GD2 (ch14.18/CHO) Antibody Treatment., PMID:34367149
Natural Killer Cells Generated From Human Induced Pluripotent Stem Cells Mature to CD56brightCD16+NKp80+/-In-Vitro and Express KIR2DL2/DL3 and KIR3DL1., PMID:34017328
Cytoplasmic Expression of CD3ε Heterodimers by Flow Cytometry Rapidly Distinguishes Between Mature T-Cell and Natural Killer-Cell Neoplasms., PMID:32589191
Follicular lymphoma patients with KIR2DL2 and KIR3DL1 and their ligands (HLA-C1 and HLA-Bw4) show improved outcome when receiving rituximab., PMID:30871628
Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC., PMID:30698860
A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation., PMID:30679439
Autoantibodies to killer cell immunoglobulin-like receptor 3DL1 in patients with systemic lupus erythematosus., PMID:30421793
Neuroblastoma Patients' KIR and KIR-Ligand Genotypes Influence Clinical Outcome for Dinutuximab-based Immunotherapy: A Report from the Children's Oncology Group., PMID:28972044
Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival., PMID:28942035
NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts., PMID:27732638
Antibody-Dependent Cellular Cytotoxicity Activity of Effector Cells from HIV-Infected Elite and Viral Controllers., PMID:27499379
KIR3DL1 Allelic Polymorphism and HLA-B Epitopes Modulate Response to Anti-GD2 Monoclonal Antibody in Patients With Neuroblastoma., PMID:27069083
KIR3DL1 interaction with HLA-B27 is altered by ankylosing spondylitis associated ERAP1 and enhanced by MHC class I cross-linking., PMID:26321090
Phenotypical and functional profiles of natural killer cells exhibiting matrix metalloproteinase-mediated CD16 cleavage after anti-HIV antibody-dependent activation., PMID:25644502
[Phenotype and functions of natural killer cells in septic patients and its clinical significance]., PMID:25399899
NKG2A expression and impaired function of NK cells in patients with new onset of Graves' disease., PMID:25281394
Expression of killer cell immunoglobulin-like receptors (KIRs) by natural killer cells during acute CMV infection after kidney transplantation., PMID:25158213
Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells., PMID:25112829
Development of a novel multiplex PCR assay to detect functional subtypes of KIR3DL1 alleles., PMID:24919192
Abnormal immunophenotype provides a key diagnostic marker: a report of 29 cases of de novo aggressive natural killer cell leukemia., PMID:24524877
Alterations in NK cell phenotype in relation to liver steatosis in children with chronic hepatitis C., PMID:23558709
Influence of cytokines on HIV-specific antibody-dependent cellular cytotoxicity activation profile of natural killer cells., PMID:22701674
NK-like T cells and plasma cytokines, but not anti-viral serology, define immune fingerprints of resilience and mild disability in exceptional aging., PMID:22028907
The first Ig domain of KIR3DL1 contacts MHC class I at a secondary site., PMID:21746965
Increased killer immunoglobulin-like receptor expression and functional defects in natural killer cells in lung cancer., PMID:21342183
Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention., PMID:21115737
Evaluation of degranulation and cytokine production in natural killer cells from spondyloarthritis patients at single-cell level., PMID:20687202
Altered natural killer (NK) cell frequency and phenotype in latent autoimmune diabetes in adults (LADA) prior to insulin deficiency., PMID:20408863
Reconstitution of natural killer cell receptors influences natural killer activity and relapse rate after haploidentical transplantation of T- and B-cell depleted grafts in children., PMID:20145268
Expression of natural killer receptors in T- and NK-cells: comparison of healthy individuals, patients with prior stem cell transplant, and patients undergoing chemotherapy., PMID:20141431
Dimorphic motifs in D0 and D1+D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide derived from HIV and HLA-A*2402., PMID:19752231
CD158k/KIR3DL2 is a useful marker for identifying neoplastic T-cells in Sézary syndrome by flow cytometry., PMID:18061949
CD158K/KIR3DL2 transcript detection in lesional skin of patients with erythroderma is a tool for the diagnosis of Sézary syndrome., PMID:17703174
Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies., PMID:17301953
Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells., PMID:17182560
T-cell large granular lymphocyte leukemias have multiple phenotypic abnormalities involving pan-T-cell antigens and receptors for MHC molecules., PMID:16416744
KIR3DL1 polymorphisms that affect NK cell inhibition by HLA-Bw4 ligand., PMID:16210627
Comparative analysis of NK cell subset distribution in normal and lymphoproliferative disease of granular lymphocyte conditions., PMID:15368309
The protein made from a common allele of KIR3DL1 (3DL1*004) is poorly expressed at cell surfaces due to substitution at positions 86 in Ig domain 0 and 182 in Ig domain 1., PMID:14662867
Functional and molecular characterization of a KIR3DL2/p140 expressing tumor-specific cytotoxic T lymphocyte clone infiltrating a human lung carcinoma., PMID:14562047
Natural killer cell receptors in cattle: a bovine killer cell immunoglobulin-like receptor multigene family contains members with divergent signaling motifs., PMID:12672064
Demonstration of aberrant T-cell and natural killer-cell antigen expression in all cases of granular lymphocytic leukaemia., PMID:12648073
Functional modulation of expanded CD8+ synovial fluid T cells by NK cell receptor expression in HLA-B27-associated reactive arthritis., PMID:11978777
Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism., PMID:11207248
Human histocompatibility leukocyte antigen (HLA)-G molecules inhibit NKAT3 expressing natural killer cells., PMID:9053439
For research use only. Not for human or drug use.
