Catalog No.
RHE34801
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, IHC: 1:200-1:1000
Target
GRIA3, GluA3, GluR-C, GLURC, GluR-K3, AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, Glutamate receptor 3, GluR-3, GLUR3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P42263
Applications
ELISA, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3K75
Long-term exposure to anti-GluA3 antibodies triggers functional and structural changes in hippocampal neurons., PMID:39954743
The correlation of GluR3B antibody with T lymphocyte subsets and inflammatory factors and their role in the progression of epilepsy., PMID:39350251
An unusual case of coma related to glutamate receptor 3 (GluR3) auto-antibodies after a traumatic spinal cord injury: Clinical and pathological aspects., PMID:33331219
Protection or susceptibility to devastating childhood epilepsy: Nodding Syndrome associates with immunogenetic fingerprints in the HLA binding groove., PMID:32639997
Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells., PMID:32561150
Monitoring the glycosylation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate-type glutamate receptors using specific antibodies reveals a novel regulatory mechanism of N-glycosylation occupancy by molecular chaperones in mice., PMID:31958346
Anti-GluA3 antibodies in frontotemporal dementia: effects on glutamatergic neurotransmission and synaptic failure., PMID:31784278
Anti-AMPA GluA3 antibodies in Frontotemporal dementia: a new molecular target., PMID:28751743
Autoimmune Frontotemporal Dementia: A New Nosological Entity?, PMID:28338508
O-GlcNAc transferase regulates excitatory synapse maturity., PMID:28143929
GluR3B Ab's induced oligodendrocyte precursor cells excitotoxicity via mitochondrial dysfunction., PMID:28063880
Hippocampal receptor complexes paralleling LTP reinforcement in the spatial memory holeboard test in the rat., PMID:25639541
Nuclear receptors in pancreatic tumor cells., PMID:25503115
Glutamate receptor antibodies directed against AMPA receptors subunit 3 peptide B (GluR3B) can be produced in DBA/2J mice, lower seizure threshold and induce abnormal behavior., PMID:24636507
Glutamate receptor antibodies directed against AMPA receptors subunit 3 peptide B (GluR3B) associate with some cognitive/psychiatric/behavioral abnormalities in epilepsy patients., PMID:24485494
Extrarolandic electroclinical findings in the evolution of adult-onset Rasmussen's encephalitis., PMID:23892576
Amacrine and bipolar inputs to midget and parasol ganglion cells in marmoset retina., PMID:22564345
Monaural conductive hearing loss alters the expression of the GluA3 AMPA and glycine receptor α1 subunits in bushy and fusiform cells of the cochlear nucleus., PMID:22044924
Expression of various glutamate receptors including N-methyl-D-aspartate receptor (NMDAR) in an ovarian teratoma removed from a young woman with anti-NMDAR encephalitis., PMID:20930449
Regulation of AMPA receptor channels and synaptic plasticity by cofilin phosphatase Slingshot in cortical neurons., PMID:20442266
Eponym : Rasmussen syndrome., PMID:20177700
Linking supply to demand: the neuronal monocarboxylate transporter MCT2 and the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid receptor GluR2/3 subunit are associated in a common trafficking process., PMID:19453627
The selective vulnerability of retinal ganglion cells in rat chronic ocular hypertension model at early phase., PMID:19396539
Human T-leukemia and T-lymphoma express glutamate receptor AMPA GluR3, and the neurotransmitter glutamate elevates the cancer-related matrix-metalloproteinases inducer CD147/EMMPRIN, MMP-9 secretion and engraftment of T-leukemia in vivo., PMID:19391040
Neurokinin 1 receptor-expressing projection neurons in laminae III and IV of the rat spinal cord have synaptic AMPA receptors that contain GluR2, GluR3 and GluR4 subunits., PMID:19200070
Neuronal enriched endosomal protein of 21 kDa colocalizes with glutamate receptor subunit GLUR2/3 at the postsynaptic membrane., PMID:19063943
Localization and functional mapping of AMPA receptor subunits in the developing rabbit retina., PMID:18676624
N-ethylmaleimide-sensitive fusion protein (NSF) is involved in central sensitization in the spinal cord through GluR2 subunit composition switch after inflammation., PMID:18598260
TCR activation eliminates glutamate receptor GluR3 from the cell surface of normal human T cells, via an autocrine/paracrine granzyme B-mediated proteolytic cleavage., PMID:17202328
Intractable myoclonus associated with anti-GluR3 antibodies after allogeneic bone marrow transplantation., PMID:17194668
Autoantibodies against an extracellular peptide of the GluR3 subtype of AMPA receptors activate both homomeric and heteromeric AMPA receptor channels., PMID:16967334
No effect of immunomodulatory therapy in focal epilepsy with positive glutamate receptor type 3--antibodies., PMID:16621617
Early response of neurons and glial cells to hypoxia in the retina., PMID:16505051
Immunocytochemical localization of metabotropic (mGluR2/3 and mGluR4a) and ionotropic (GluR2/3) glutamate receptors in adrenal medullary ganglion cells., PMID:16329038
Antibodies to glutamate receptor subtype 3 (GluR3) are found in some patients suffering from epilepsy as the main disease, but not in patients whose epilepsy accompanies antiphospholipid syndrome or Sneddon's syndrome., PMID:16278146
Antiglial cell autoantibodies and childhood epilepsy: a case report., PMID:16060945
Autoimmune epilepsy: distinct subpopulations of epilepsy patients harbor serum autoantibodies to either glutamate/AMPA receptor GluR3, glutamate/NMDA receptor subunit NR2A or double-stranded DNA., PMID:15978777
Transmitter content, origins and connections of axons in the spinal cord that possess the serotonin (5-hydroxytryptamine) 3 receptor., PMID:15975728
Immunization with the glutamate receptor-derived peptide GluR3B induces neuronal death and reactive gliosis, but confers partial protection from pentylenetetrazole-induced seizures., PMID:15907325
Signaling complex formation of phospholipase Cbeta4 with metabotropic glutamate receptor type 1alpha and 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain., PMID:15579147
Autoimmune epilepsy: some epilepsy patients harbor autoantibodies to glutamate receptors and dsDNA on both sides of the blood-brain barrier, which may kill neurons and decrease in brain fluids after hemispherotomy., PMID:15559370
[Advances in neuroimmunological laboratory studies on neuromuscular diseases]., PMID:15552936
Absence of antibodies to glutamate receptor type 3 (GluR3) in Rasmussen encephalitis., PMID:15249609
Widespread expression of the AMPA receptor GluR2 subunit at glutamatergic synapses in the rat spinal cord and phosphorylation of GluR1 in response to noxious stimulation revealed with an antigen-unmasking method., PMID:15215299
Ionotropic glutamate receptor GluR2/3-immunoreactive neurons in the cat, rabbit, and hamster superficial superior colliculus., PMID:15140557
Rasmussen's syndrome., PMID:14598051
New autoantibody mediated disorders of the central nervous system., PMID:12858073
Glutamate receptor subunit 3 (GluR3) immunoreactivity delineates a subpopulation of parvalbumin-containing interneurons in the rat hippocampus., PMID:12761821
Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration., PMID:12682273
The density of AMPA receptors activated by a transmitter quantum at the climbing fibre-Purkinje cell synapse in immature rats., PMID:12665613
For research use only. Not for human or drug use.
