Catalog No.
RHE31801
Species reactivity
Human, Mouse, Rat, Monkey
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000
Target
C-Src kinase, Tyrosine-protein kinase CSK, Protein-tyrosine kinase CYL, CSK
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P41240
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3K61
Synthesis of the Pentasaccharide Unit of the Pseudomonas aeruginosa Exopolysaccharide Psl Conjugation with CRM197, and Evaluation of Antigenicity in a QS-21/Pam3CSK4-Liposomal Formulation., PMID:40333663
Adjuvant Templating Improves On-Target/Off-Target Antibody Ratio Better than Linker Addition for M2-Derived Peptide Amphiphile Micelle Vaccines., PMID:40333333
Toll-like receptor 1/2 activation reduces immunoglobulin free light chain production by multiple myeloma cells in the context of bone marrow stromal cells and fibronectin., PMID:39874349
Focal Adhesion Kinase (FAK) and c-Src Dependent Signal Transduction in Cell Adhesion., PMID:39463220
Distribution of maedi-visna virus in different organs of the spontaneously affected small ruminants in India., PMID:39156799
Distinct maturation, glucose metabolism, and inflammatory function of human monocytes-derived IDECs mediated by anti-IgE and Pam3CSK4 alone or in combination., PMID:39086490
Nipocalimab, an anti-FcRn monoclonal antibody, in participants with moderate to severe active rheumatoid arthritis and inadequate response or intolerance to anti-TNF therapy: results from the phase 2a IRIS-RA study., PMID:38942592
Csk restrains BCR-mediated ROS production and contributes to germinal center selection and affinity maturation., PMID:38753246
Anti-HLA Immunization in Patients After Lung Transplantation: A Comparative Study Before and During the Pandemic., PMID:38729828
Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas., PMID:38701792
TLR Engagement Induces an Alternate Pathway for BCR Signaling that Results in PKCδ Phosphorylation., PMID:38629913
Synthesis and immunological evaluation of TLR1/2 ligand-conjugated RBDs as self-adjuvanting vaccine candidates against SARS-CoV-2., PMID:38497901
Oxidative Stress Participates in Age-Related Cataract Formation by Disrupting Connection between Lens Epithelial Cells through c-Src/VEGF Pathway., PMID:38108278
Protocol to characterize extracellular c-Src tyrosine kinase function through substrate interaction and phosphorylation., PMID:38043058
Tularemia - a re-emerging disease with growing concern., PMID:37916743
STAP-2 negatively regulates BCR-mediated B cell activation by recruiting tyrosine-protein kinase CSK to LYN., PMID:37669828
Predicting the changes in neutralizing antibody interaction with G protein derived from Bangladesh isolates of Nipah virus: molecular dynamics based approach., PMID:37643003
Cell Entry of Avian Reovirus Modulated by Cell-Surface Annexin A2 and Adhesion G Protein-Coupled Receptor Latrophilin-2 Triggers Src and p38 MAPK Signaling Enhancing Caveolin-1- and Dynamin 2-Dependent Endocytosis., PMID:37097149
Induction of a strong and long-lasting neutralizing immune response by dPreS1-TLR2 agonist nanovaccine against hepatitis B virus., PMID:36496142
Precise immunological evaluation rationalizes the design of a self-adjuvanting vaccine composed of glycan antigen, TLR1/2 ligand, and T-helper cell epitope., PMID:35873332
Stereoisomeric Pam2CS based TLR2 agonists: synthesis, structural modelling and activity as vaccine adjuvants., PMID:35694694
Synthesis and functional studies of self-adjuvanting multicomponent anti-HER2 cancer vaccines., PMID:35497522
A Novel Toll-Like Receptor 2 Agonist Protects Mice in a Prophylactic Treatment Model Against Challenge With Bacillus anthracis., PMID:35369443
Novel Synthetic Lipopeptides as Potential Mucosal Adjuvants Enhanced SARS-CoV-2 rRBD-Induced Immune Response., PMID:35356002
The different overall survival between single-agent EGFR-TKI treatment and with bevacizumab in non-small cell lung cancer patients with brain metastasis., PMID:35292755
Leukemia cutis in accelerated chronic lymphocytic leukemia: successful treatment with venetoclax and rituximab., PMID:35187604
MPLA-Adjuvanted Liposomes Encapsulating S-Trimer or RBD or S1, but Not S-ECD, Elicit Robust Neutralization Against SARS-CoV-2 and Variants of Concern., PMID:35108485
RBD conjugate vaccine with a built-in TLR1/2 agonist is highly immunogenic against SARS-CoV-2 and variants of concern., PMID:35040862
Single-dose of adrecizumab versus placebo in acute cardiogenic shock (ACCOST-HH): an investigator-initiated, randomised, double-blinded, placebo-controlled, multicentre trial., PMID:34895483
Efficacy and safety of guselkumab in patients with active psoriatic arthritis who are inadequate responders to tumour necrosis factor inhibitors: results through one year of a phase IIIb, randomised, controlled study (COSMOS)., PMID:34819273
Efficacy of first-line atezolizumab combination therapy in patients with non-small cell lung cancer receiving proton pump inhibitors: post hoc analysis of IMpower150., PMID:34711947
Impacts of Quarterly Sow Mass Vaccination with a Porcine Reproductive and Respiratory Syndrome Virus Type 1 (PRRSV-1) Modified Live Vaccine in Two Herds., PMID:34696165
NK Cell-Dependent Antibody-Mediated Immunotherapy Is Improved In Vitro and In Vivo When Combined with Agonists for Toll-like Receptor 2 in Head and Neck Cancer Models., PMID:34681717
Isolated Lower Motor Neuron Type Facial Palsy Following Hematotoxic Snake Envenomation., PMID:34435327
Guselkumab demonstrated an independent treatment effect in reducing fatigue after adjustment for clinical response-results from two phase 3 clinical trials of 1120 patients with active psoriatic arthritis., PMID:34261541
Novel 1,2,3-triazole-tethered Pam3CAG conjugates as potential TLR-2 agonistic vaccine adjuvants., PMID:33848722
Cutaneous leukocytoclastic vasculitis at diagnosis of hairy cell leukemia successfully treated with vemurafenib and rituximab., PMID:33831657
Correspondence on 'SARS-CoV-2 antibody response after COVID-19 in patients with rheumatic disease'., PMID:33692021
Increased Expression of PPAR-γ Modulates Monocytes Into a M2-Like Phenotype in SLE Patients: An Implicative Protective Mechanism and Potential Therapeutic Strategy of Systemic Lupus Erythematosus., PMID:33584646
Guselkumab, an inhibitor of the IL-23p19 subunit, provides sustained improvement in signs and symptoms of active psoriatic arthritis: 1 year results of a phase III randomised study of patients who were biologic-naïve or TNFα inhibitor-experienced., PMID:33568556
Giardia intestinalis coiled-coil cytolinker protein 259 interacts with actin and tubulin., PMID:33515065
Efficacy, Safety, and Immunogenicity of Insulin Aspart Biosimilar SAR341402 Compared with Originator Insulin Aspart in Adults with Diabetes (GEMELLI 1): A Subgroup Analysis by Prior Type of Mealtime Insulin., PMID:33432547
Current Treatment of Refractory/Relapsed Chronic Lymphocytic Leukemia: A Focus on Novel Drugs., PMID:33238270
Pam3CSK4-CDGSF Augments Antitumor Immunotherapy by Synergistically Activating TLR1/2 and STING., PMID:33147965
Impact of guselkumab, an interleukin-23 p19 subunit inhibitor, on enthesitis and dactylitis in patients with moderate to severe psoriatic arthritis: results from a randomised, placebo-controlled, phase II study., PMID:32665433
Immunological Evaluation of Co-Assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants: Self-Adjuvanting Anti-Breast-Cancer Vaccine Candidates., PMID:32583549
[Effects of brain necroptosis and cytokines expression array on brain injury in rats with cardiac arrest]., PMID:32527358
Early tumor shrinkage identifies long-term disease control and survival in patients with lung cancer treated with atezolizumab., PMID:32503948
Effects of ustekinumab on spondylitis-associated endpoints in TNFi-naïve active psoriatic arthritis patients with physician-reported spondylitis: pooled results from two phase 3, randomised, controlled trials., PMID:32209721
PTPN22 phosphorylation acts as a molecular rheostat for the inhibition of TCR signaling., PMID:32184287
For research use only. Not for human or drug use.
