Catalog No.
RHE29501
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
WB: 1:500-1:2000
Target
Ets-related protein ERM, ERM, ETV5, ETS translocation variant 5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P41161
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3K48
E-twenty-six-specific sequence variant 5 (ETV5) facilitates hepatocellular carcinoma progression and metastasis through enhancing polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC)-mediated immunosuppression., PMID:40015948
ETV5 promotes lupus pathogenesis and follicular helper T cell differentiation by inducing osteopontin expression., PMID:38843187
ETS translocation variant 5 (ETV5) promotes CD4+ T cell-mediated intestinal inflammation and fibrosis in inflammatory bowel diseases., PMID:38555025
Human Blood Serum Inhibits Ductal Carcinoma Cells BT474 Growth and Modulates Effect of HER2 Inhibition., PMID:36009461
Transcriptome and chromatin landscape changes associated with trastuzumab resistance in HER2+ breast cancer cells., PMID:34224831
Targeting tumor cell-derived CCL2 as a strategy to overcome Bevacizumab resistance in ETV5+ colorectal cancer., PMID:33099574
Pseudogene Associated Recurrent Gene Fusion in Prostate Cancer., PMID:31446281
Chromosome 3q arm gain linked to immunotherapy response in advanced cutaneous squamous cell carcinoma., PMID:30954880
Systems analysis identifies potential target genes to overcome cetuximab resistance in colorectal cancer cells., PMID:30719834
ETS variant 5 promotes colorectal cancer angiogenesis by targeting platelet-derived growth factor BB., PMID:30650178
ICAM3 mediates tumor metastasis via a LFA-1-ICAM3-ERM dependent manner., PMID:29729315
Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5., PMID:28855737
Identification of Pharmacodynamic Transcript Biomarkers in Response to FGFR Inhibition by AZD4547., PMID:27550940
Yap and Taz are required for Ret-dependent urinary tract morphogenesis., PMID:26243870
Ras/ERK1/2 pathway regulates the self-renewal of dairy goat spermatogonia stem cells., PMID:25820901
Identification of Ezrin-Radixin-Moesin proteins as novel regulators of pathogenic B-cell receptor signaling and tumor growth in diffuse large B-cell lymphoma., PMID:25801911
ETV5 transcription program links BDNF and promotion of EMT at invasive front of endometrial carcinomas., PMID:25233929
Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer., PMID:25203299
A role for CD81 and hepatitis C virus in hepatoma mobility., PMID:24662676
The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism., PMID:21501826
Proteomic approach to ETV5 during endometrial carcinoma invasion reveals a link to oxidative stress., PMID:19443906
Identification of mesenchymal stem cell (MSC)-transcription factors by microarray and knockdown analyses, and signature molecule-marked MSC in bone marrow by immunohistochemistry., PMID:19228201
The Pea3 Ets transcription factor regulates differentiation of multipotent progenitor cells during mammary gland development., PMID:18977342
Etv5, an ETS transcription factor, is expressed in granulosa and cumulus cells and serves as a transcriptional regulator of the cyclooxygenase-2., PMID:18492810
Effects of ETV5 (ets variant gene 5) on testis and body growth, time course of spermatogonial stem cell loss, and fertility in mice., PMID:18032421
Functional binding interaction identified between the axonal CAM L1 and members of the ERM family., PMID:12070130
Embryonic gene expression resolved at the cellular level by fluorescence in situ hybridization., PMID:10429965
Expression of the PEA3 group of ETS-related transcription factors in human breast-cancer cells., PMID:9052761
Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members., PMID:8207064