Anti-OTX2 Antibody (R3J32)

Catalog No.

RHD99101

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Orthodenticle homolog 2, OTX2, Homeobox protein OTX2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P32243

Applications

ELISA, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3J32

OTX-2 Expression as a Diagnostic Marker for Choroid Plexus Tumors., PMID:39988363

c-Jun N-terminal kinase 1 (JNK1) phosphorylates OTX2 transcription factor that regulates early retinal development., PMID:36434388

Retinoic acid and taurine enhance differentiation of the human bone marrow stem cells into cone photoreceptor cells and retinal ganglion cells., PMID:34569079

Initiation of Otx2 expression in the developing mouse retina requires a unique enhancer and either Ascl1 or Neurog2 activity., PMID:34143204

Diagnostic Accuracy of a Reduced Immunohistochemical Panel in Medulloblastoma Molecular Subtyping, Correlated to DNA-methylation Analysis., PMID:33323893

Reconsideration of the Semaphorin-3A Binding Motif Found in Chondroitin Sulfate Using Galnac4s-6st-Knockout Mice., PMID:33143303

OTX2 Non-Cell Autonomous Activity Regulates Inner Retinal Function., PMID:32737182

Homeoprotein OTX1 and OTX2 involvement in rat myenteric neuron adaptation after DNBS-induced colitis., PMID:32095330

Role of the TAp63 Isoform in Recurrent Nasal Polyps., PMID:31903890

Generation of functional dopaminergic neurons from human spermatogonial stem cells to rescue parkinsonian phenotypes., PMID:31248447

New genetic findings in a large cohort of congenital hypogonadotropic hypogonadism., PMID:31200363

Ventricular Meningiomas: Surgical Strategies and a New Finding That Suggest an Origin From the Choroid Plexus Epithelium., PMID:31121376

OTX2 Signals from the Choroid Plexus to Regulate Adult Neurogenesis., PMID:31064838

Evaluation of the Capability of the Wharton's Jelly Mesenchymal Stem Cell Aggregates to Express the Markers of Three Germ Cell Lineages., PMID:30980644

Genome-wide association study suggests four variants influencing outcomes with ranibizumab therapy in exudative age-related macular degeneration., PMID:30054556

Structural Variation of Chondroitin Sulfate Chains Contributes to the Molecular Heterogeneity of Perineuronal Nets., PMID:29456495

Increased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiation., PMID:28050121

Retinal Pigment Epithelium Responses to Selective Retina Therapy in Mouse Eyes., PMID:27367516

Hand1 overexpression inhibits medulloblastoma metastasis., PMID:27297109

A Mouse Model for Conditional Secretion of Specific Single-Chain Antibodies Provides Genetic Evidence for Regulation of Cortical Plasticity by a Non-cell Autonomous Homeoprotein Transcription Factor., PMID:27171438

Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex., PMID:25165539

Stem cell profiling in head and neck cancer reveals an Oct-4 expressing subpopulation with properties of chemoresistance., PMID:24387977

Isolated prolactin deficiency associated with serum autoantibodies against prolactin-secreting cells., PMID:23940128

Experience-dependent development of perineuronal nets and chondroitin sulfate proteoglycan receptors in mouse visual cortex., PMID:23597636

MiR-206 regulates neural cells proliferation and apoptosis via Otx2., PMID:22508046

Generation of retinal ganglion-like cells from reprogrammed mouse fibroblasts., PMID:20484577

Ectopic Mitf in the embryonic chick retina by co-transfection of β-catenin and Otx2., PMID:20463321

A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression., PMID:20447394

Molecular characterization of human retinal progenitor cells., PMID:19553622

The lens-regenerating competence in the outer cornea and epidermis of larval Xenopus laevis is related to pax6 expression., PMID:18430088

A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors., PMID:17980036

Differentially expressed genes are marked by histone 3 lysine 9 trimethylation in human cancer cells., PMID:17968314

Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion., PMID:16243537

Retinoic acid-mediated induction of neurons and glial cells from human umbilical cord-derived hematopoietic stem cells., PMID:14743441

Transcription factors of the anterior neural plate alter cell movements of epidermal progenitors to specify a retinal fate., PMID:11784048

Temporal and spatial effects of Sonic hedgehog signaling in chick eye morphogenesis., PMID:11336495

The subcellular localization of Otx2 is cell-type specific and developmentally regulated in the mouse retina., PMID:10891582

Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures., PMID:10751172

The role of intracellular alkalinization in the establishment of anterior neural fate in Xenopus., PMID:9466884

The caudal limit of Otx2 gene expression as a marker of the midbrain/hindbrain boundary: a study using in situ hybridisation and chick/quail homotopic grafts., PMID:9012500

OTX2 homeoprotein in the developing central nervous system and migratory cells of the olfactory area., PMID:8887325

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