Catalog No.
RHD87203
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200
Target
Prostatic-binding protein, PEBP-1, HCNP, PEBP, PEBP1, Neuropolypeptide h3, Raf kinase inhibitor protein, Phosphatidylethanolamine-binding protein 1, PBP, HCNPpp, RKIP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P30086
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3H92
Dihydroberberine alleviates Th17/Treg imbalance in premature ovarian insufficiency mice via inhibiting Rheb/mTOR signaling., PMID:39472803
Serum protein biomarker profile distinguishes acetylcholine receptor antibody seropositive myasthenia gravis patients from healthy controls., PMID:39165841
Enhanced Antipediatric Sarcoma Effect of Everolimus with Secukinumab by Targeting IL17A., PMID:38295302
Evaluating Low HER2 Status in Invasive Breast Carcinoma via HER2 Immunohistochemistry, with HER2 FISH Correlation: A Cohort of 112 Patients., PMID:37664543
Cyclosporine plus eltrombopag in the treatment of aplastic anemia with or without antithymocyte immunoglobulin: A multicenter real-world retrospective study., PMID:37271577
mTORC1 signaling pathway regulates tooth repair., PMID:36927863
Clinical implications of the interaction between PD-1/PD-L1 and PI3K/AKT/mTOR pathway in progression and treatment of non-small cell lung cancer., PMID:36313041
Profiling of extracellular vesicles of metastatic urothelial cancer patients to discover protein signatures related to treatment outcome., PMID:35838333
Dual synergistic response for the electrochemical detection of H1N1 virus and viral proteins using high affinity peptide receptors., PMID:35653962
The expression and significance of p4E-BP1/4E-BP1 in prostate cancer., PMID:35257419
Digitoxin promotes apoptosis and inhibits proliferation and migration by reducing HIF-1α and STAT3 in KRAS mutant human colon cancer cells., PMID:34717917
Amino acids and mechanistic target of rapamycin regulate the fate of live engulfed cells., PMID:34547144
Effects of Vaccination Against Coccidiosis on Gut Microbiota and Immunity in Broiler Fed Bacitracin and Berry Pomace., PMID:34149685
Regulation of the mammalian maternal-to-embryonic transition by eukaryotic translation initiation factor 4E., PMID:34013332
Curcumin promotes cell cycle arrest and apoptosis of acute myeloid leukemia cells by inactivating AKT., PMID:33649826
The relationship between the mTOR signaling pathway and ovarian aging in peak-phase and late-phase laying hens., PMID:33357698
Construction of a nitro-oxidative stress-driven, mechanistic model of mood disorders: A nomothetic network approach., PMID:33186727
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression., PMID:33127842
Differential Targeting of Gr-MDSCs, T Cells and Prostate Cancer Cells by Dactolisib and Dasatinib., PMID:32230980
Bullous Pemphigoid and Malignancy in Two Different Hospital Populations: A Retrospective Cohort Review., PMID:32182611
Increased Serum Immunoglobulin Responses to Gut Commensal Gram-Negative Bacteria in Unipolar Major Depression and Bipolar Disorder Type 1, Especially When Melancholia Is Present., PMID:31802379
CCN1 stimulated the osteoblasts via PTEN/AKT/GSK3β/cyclinD1 signal pathway in Myeloma Bone Disease., PMID:31769620
Mechanism of AMPK-mediated apoptosis of rat gastric smooth muscle cells under high glucose condition., PMID:31769476
Upregulation of the nitrosylome in bipolar disorder type 1 (BP1) and major depression, but not BP2: Increased IgM antibodies to nitrosylated conjugates are associated with indicants of leaky gut., PMID:31323278
MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling., PMID:31319869
Immunophenotyping of Murine Precursor B-Cell Leukemia/Lymphoma: A Comparison of Immunohistochemistry and Flow Cytometry., PMID:31170889
Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data., PMID:31057298
Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation., PMID:30885218
Selenium deficiency impaired immune function of the immune organs in young grass carp (Ctenopharyngodon idella)., PMID:29559270
Anti-CD69 therapy induces rapid mobilization and high proliferation of HSPCs through S1P and mTOR., PMID:29483712
Discrepancy Between Low Levels of mTOR Activity and High Levels of P-S6 in Primary Central Nervous System Lymphoma May Be Explained by PAS Domain-Containing Serine/Threonine-Protein Kinase-Mediated Phosphorylation., PMID:29361117
Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis., PMID:29359350
Deciphering the pathways that protect from IL-13-mediated potentiation of oxidative stress-induced dopaminergic nerve cell death., PMID:28969943
Threonine deficiency decreased intestinal immunity and aggravated inflammation associated with NF-κB and target of rapamycin signalling pathways in juvenile grass carp (Ctenopharyngodon idella) after infection with Aeromonas hydrophila., PMID:28820083
Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice., PMID:28395173
MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody., PMID:28341789
Reciprocal regulation of mTOR complexes in pancreatic islets from humans with type 2 diabetes., PMID:28004151
mTORC1 signalling and eIF4E/4E-BP1 translation initiation factor stoichiometry influence recombinant protein productivity from GS-CHOK1 cells., PMID:27760840
Role of mTOR signaling pathway in the pathogenesis of subependymal giant cell astrocytoma - A study of 28 cases., PMID:27625244
Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins., PMID:27556570
Mitotic protein kinase CDK1 phosphorylation of mRNA translation regulator 4E-BP1 Ser83 may contribute to cell transformation., PMID:27402756
Phenotypically Dormant and Immature Leukaemia Cells Display Increased Ribosomal Protein S6 Phosphorylation., PMID:26985829
Schedule-dependent interaction between temsirolimus and cetuximab in head and neck cancer: a preclinical study., PMID:26982238
GD2 ganglioside specific antibody treatment downregulates PI3K/Akt/mTOR signaling network in human neuroblastoma cell lines., PMID:26134970
RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia., PMID:25999352
FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth., PMID:25880415
Paricalcitol counteracts the increased contrast induced nephropathy caused by renin-angiotensin-aldosterone system blockade therapy in a rat model., PMID:25339484
Effects of targeting endometrial stromal sarcoma cells via histone deacetylase and PI3K/AKT/mTOR signaling., PMID:24922651
Everolimus inhibits anti-HLA I antibody-mediated endothelial cell signaling, migration and proliferation more potently than sirolimus., PMID:24580843
The immunosuppressant tributyltin oxide blocks the mTOR pathway, like rapamycin, albeit by a different mechanism., PMID:24375594
For research use only. Not for human or drug use.
