Catalog No.
RHD73614
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100
Target
Microtubule-associated protein 2 kinase, p44-MAPK, Extracellular signal-regulated kinase 1, ERK1, MAPK3, MAP kinase isoform p44, Mitogen-activated protein kinase 3, ERK-1, PRKM3, Insulin-stimulated MAP2 kinase, p44-ERK1, MAPK 3, MAP kinase 3, ERT2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P27361
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3H29
Oleanolic acid inhibits mesangial cell proliferation and inflammatory response in mesangial proliferative glomerulonephritis through IL-17/ERK/AKT pathway., PMID:40088868
Association Between Peptide Antigen-Related Antibody Levels and the Short- and Long-Term Efficacy of Antipsychotic Treatment in Drug-Naïve First-Episode Schizophrenia Patients., PMID:39673496
Effects of Viscum coloratum (Kom.) Nakai on collagen-induced rheumatoid arthritis., PMID:38490288
Characteristics of Serum Autoantibody Repertoire and Immune Subgroup Variation of Tuberculosis-Associated Obstructive Pulmonary Disease., PMID:38075560
IL-33 Suppresses the Progression of Atherosclerosis via the ERK1/2-IRF1-VCAM-1 Pathway., PMID:37957490
Discovery of natural multi-targets neuraminidase inhibitor glycosides compounds against influenza A virus through network pharmacology, virtual screening, molecular dynamics simulation, and in vitro experiment., PMID:37743355
Epigallocatechin-3-Gallate, an Active Green Tea Component to Support Anti-VEGFA Therapy in Wet Age-Related Macular Degeneration., PMID:37571296
Artificial Neural Networks Predicted the Overall Survival and Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Pancancer Immune-Oncology Panel., PMID:34945004
Current and emerging therapies for advanced biliary tract cancers., PMID:34626563
Krüppel-Like Factor 15/Interleukin 11 Axis-Mediated Adventitial Remodeling Depends on Extracellular Signal-Regulated Kinases 1 and 2 Activation in Angiotensin II-Induced Hypertension., PMID:34350769
Galectin‑3 blockade suppresses the growth of cetuximab‑resistant human oral squamous cell carcinoma., PMID:34328195
Resveratrol Is a Natural Inhibitor of Human Intestinal Mast Cell Activation and Phosphorylation of Mitochondrial ERK1/2 and STAT3., PMID:34299258
Inhibitors of PD-1/PD-L1 and ERK1/2 impede the proliferation of receptor positive and triple-negative breast cancer cell lines., PMID:34185141
Unconventional Secretion of PKCδ Exerts Tumorigenic Function via Stimulation of ERK1/2 Signaling in Liver Cancer., PMID:33318039
HGF-Induced PD-L1 Expression in Head and Neck Cancer: Preclinical and Clinical Findings., PMID:33233528
Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines., PMID:33115415
The cAMP-ERK1/2 signaling pathway regulates urokinase-type plasminogen activator-induced bovine granulosa cell proliferation., PMID:33112787
POU4F1 confers trastuzumab resistance in HER2-positive breast cancer through regulating ERK1/2 signaling pathway., PMID:32988584
Serum ERK1/2 proteins fluctuating with HBV infection report frequency of viral-specific CD8+ T cells and predict IFNα therapeutic effect in chronic hepatitis B patients., PMID:32791312
Expression and function of the nonclassical estrogen receptor, GPR30, in human cartilage and chondrocytes., PMID:32324271
Transcripts 202 and 205 of IL-6 confer resistance to Vemurafenib by reactivating the MAPK pathway in BRAF(V600E) mutant melanoma cells., PMID:32173467
Functional effects of Tribbles homolog 2 in bovine ovarian granulosa cells†., PMID:32159216
Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome., PMID:32028069
Nox4-mediated ROS production is involved, but not essential for TGFβ-induced lens EMT leading to cataract., PMID:31926131
Cyclosporin A activates human hepatocellular carcinoma (HepG2 cells) proliferation: implication of EGFR-mediated ERK1/2 signaling pathway., PMID:31907582
IL-17 alters the mesenchymal stem cell niche towards osteogenesis in cooperation with osteocytes., PMID:31643095
Novel MRGPRX2 antagonists inhibit IgE-independent activation of human umbilical cord blood-derived mast cells., PMID:31299111
CXCL2 attenuates osteoblast differentiation by inhibiting the ERK1/2 signaling pathway., PMID:31292171
Involvement of miR-770-5p in trastuzumab response in HER2 positive breast cancer cells., PMID:31009516
HIV-1 infection modulates IL-24 expression which contributes to cell apoptosis in vitro., PMID:30761646
Human G protein-coupled receptor 30 is N-glycosylated and N-terminal domain asparagine 44 is required for receptor structure and activity., PMID:30760632
Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease: A Secondary Analysis of the Exenatide-PD Trial., PMID:30640362
PTHrP treatment of colon cancer cells promotes tumor associated-angiogenesis by the effect of VEGF., PMID:30639585
Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells., PMID:30513286
Endothelin-1 triggers human peritoneal mesothelial cells' proliferation via ERK1/2-Ets-1 signaling pathway and contributes to endothelial cell angiogenesis., PMID:30485480
Alterations of MEK1/2-ERK1/2, IFNγ and Smad2/3 associated Signalling pathways during cryopreservation of ASCs affect their differentiation towards VSMC-like cells., PMID:30273905
Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway., PMID:29449532
A comparative global phosphoproteomics analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment., PMID:29371955
Detection of MAPK3/6 Phosphorylation During Hypersensitive Response (HR)-Associated Programmed Cell Death in Plants., PMID:29332294
Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer., PMID:29326975
Gene signatures related to HAI response following influenza A/H1N1 vaccine in older individuals., PMID:27441275
Intracrine VEGF Signaling Mediates the Activity of Prosurvival Pathways in Human Colorectal Cancer Cells., PMID:26988990
Transcriptomic changes associated with DKK4 overexpression in pancreatic cancer cells detected by RNA-Seq., PMID:26880586
Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells., PMID:26716417
Bisphenol A and Related Alkylphenols Exert Nongenomic Estrogenic Actions Through a G Protein-Coupled Estrogen Receptor 1 (Gper)/Epidermal Growth Factor Receptor (Egfr) Pathway to Inhibit Meiotic Maturation of Zebrafish Oocytes., PMID:26490843
Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection., PMID:26046590
Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells., PMID:25948584
Effect of the transient pharmacological inhibition of Mapk3/1 pathway on ovulation in mice., PMID:25803847
Cyclic guanosine monophosphate does not inhibit gonadotropin-induced activation of mitogen-activated protein kinase 3/1 in pig cumulus-oocyte complexes., PMID:25567742
The C-type lectin OCILRP2 costimulates EL4 T cell activation via the DAP12-Raf-MAP kinase pathway., PMID:25411776
For research use only. Not for human or drug use.
