Catalog No.
YHD41301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu19-Leu246
Predicted molecular weight
27.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20718
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CTSGL2, CCP-X, Cathepsin G-like 2, CGL2, Cytotoxic serine protease C, CSP-C, GZMH, Cytotoxic T-lymphocyte proteinase, Granzyme H
N6-methyladenosine RNA base modification regulates NKG2D-dependent and cytotoxic genes expression in natural killer cells., PMID:40389988
Sheep pan-genome retrieves the lost sequences and genes during domestication and selection., PMID:40258447
Mechanistic insights into COVID-19 mRNA vaccine-associated myocarditis: a bioinformatics analysis., PMID:40226040
Single cell transcriptome sequencing indicates the cellular heterogeneity of small intestine tissue in celiac disease., PMID:40216823
Association of the characteristics of brain magnetic resonance imaging with genes related to disease onset in schizophrenia patients., PMID:40158807
Exploring gene expression, alternative splicing events and RNA-binding proteins changes in PBMC from patients with hyperuricemia., PMID:39828062
Metabolic remodeling in glioblastoma: a longitudinal multi-omics study., PMID:39394177
Targeted proteomics profiling reveals valuable biomarkers in the diagnosis of primary immune thrombocytopaenia., PMID:39313912
Identification of key immune-related genes and potential therapeutic targets in immune checkpoint inhibitor-associated myocarditis., PMID:39251231
Validating the temporal performance of genetic biomarkers in an animal model of recurrence/ non-recurrence myocardial infarction persuades by bioinformatics tools., PMID:38950836
Peripheral Blood CD8+ T-Lymphocyte Immune Response in Benign and Subpopulations of Breast Cancer Patients., PMID:38928129
Potential marker genes for chronic obstructive pulmonary disease revealed based on single-cell sequencing and Mendelian randomization analysis., PMID:38787375
Uncoupling interferons and the interferon signature explains clinical and transcriptional subsets in SLE., PMID:38744279
Tumor and Peritoneum-Associated Macrophage Gene Signature as a Novel Molecular Biomarker in Gastric Cancer., PMID:38612926
Comparative single-cell transcriptomic profile of hybrid immunity induced by adenovirus vector-based COVID-19 vaccines., PMID:38570727
Terminally differentiated cytotoxic CD4+ T cells were clonally expanded in the brain lesion of radiation-induced brain injury., PMID:38499993
Radiofrequency ablation plays double role in immunosuppression and activation of PBMCs in recurrent hepatocellular carcinoma., PMID:38348038
Identification of biomarkers associated with pediatric asthma using machine learning algorithms: A review., PMID:38013370
Preferential differential gene expression within the WC1.1+ γδ T cell compartment in cattle naturally infected with Mycobacterium bovis., PMID:37942326
Trajectories of immune-related serum proteins and quality of life in patients with pancreatic and other periampullary cancer: the CHAMP study., PMID:37936126
[Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer's Disease Based on Single-Cell Transcriptome]., PMID:37866940
Dysregulation of Immune Cell Subpopulations in Atypical Hemolytic Uremic Syndrome., PMID:37373158
Identification of the candidate genes of diagnosing rheumatoid arthritis using the single-cell sequencing technology and T cell subclusters analysis of patients with rheumatoid arthritis., PMID:37235118
Deciphering the immune heterogeneity dominated by natural killer cells with prognostic and therapeutic implications in hepatocellular carcinoma., PMID:37030269
Identification of pre-infection markers and differential plasma protein expression following SARS-CoV-2 infection in people living with HIV., PMID:36966617
Nasal administration of anti-CD3 mAb (Foralumab) downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells in subjects with COVID-19., PMID:36881624
A single-cell map of peripheral alterations after FMT treatment in patients with systemic lupus erythematosus., PMID:36610264
Longitudinal single-cell analysis of a patient receiving adoptive cell therapy reveals potential mechanisms of treatment failure., PMID:36514045
Screening of Sepsis Biomarkers Based on Bioinformatics Data Analysis., PMID:36199375
Natural Killer Cells Disrupt Nerve Fibers by Granzyme H in Atheriosclerotic Cerebral Small Vessel Disease., PMID:36006802
Profiling of extracellular vesicles of metastatic urothelial cancer patients to discover protein signatures related to treatment outcome., PMID:35838333
Single Cell Transcriptome and Surface Epitope Analysis of Ankylosing Spondylitis Facilitates Disease Classification by Machine Learning., PMID:35634297
Characterization of Peripheral Blood TCR in Patients with Type 1 Diabetes Mellitus by BD RhapsodyTM VDJ CDR3 Assay., PMID:35626661
Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus., PMID:35389781
The deadly face of felid killer cells: The cytotoxic proteins and their genes., PMID:35263044
Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection., PMID:34675930
A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients., PMID:34322127
Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma., PMID:33737344
A Deadly Cargo: Gene Repertoire of Cytotoxic Effector Proteins in the Camelidae., PMID:33669939
Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity., PMID:31736981
Distinguishable Prognostic Signatures of Left- and Right-Sided Colon Cancer: a Study Based on Sequencing Data., PMID:30016783
Proteome analysis of human CD56neg NK cells reveals a homogeneous phenotype surprisingly similar to CD56dim NK cells., PMID:29999523
Regulation of antitumor miR-144-5p targets oncogenes: Direct regulation of syndecan-3 and its clinical significance., PMID:29968393
Parenclitic networks for predicting ovarian cancer., PMID:29854310
Blood RNA biomarkers in prodromal PARK4 and rapid eye movement sleep behavior disorder show role of complexin 1 loss for risk of Parkinson's disease., PMID:28108469
Granzyme H is a novel protease expressed by human mast cells., PMID:25342632
Molecular underpinning of extranodal NK/T-cell lymphoma., PMID:23768641
Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation., PMID:23352961
Altered expression of degranulation-related genes in CD8+ T cells in human T lymphotropic virus type I infection., PMID:23301858
Identification of SERPINB1 as a physiological inhibitor of human granzyme H., PMID:23269243
For research use only. Not for human or drug use.
