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Anti-Human Kappa Light Chain Antibody (R3F49)

Catalog #:   RHD36907 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: P01834
Overview

Catalog No.

RHD36907

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:500-1:1000

Target

Ig kappa chain C region EU, Ig kappa chain C region, Ig kappa chain C region ROY, Immunoglobulin kappa constant, IGKC, Ig kappa chain C region TI, Ig kappa chain C region OU, Ig kappa chain C region CUM, Ig kappa chain C region AG

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01834

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3F49

Data Image
  • Immunohistochemical
    IHC-P analysis of tonsil tissue by IGKC antibody. Immunohistochemistry was performed using sections of the formalin-fixed paraffin- embedded tonsil;Result: Germinal center cells, non-germinal center cells and squamous epithelial cells are positively stained at the cytoplasm.
References

Germline polymorphism in the immunoglobulin kappa and lambda loci explain variation in the expressed light chain antibody repertoire., PMID:40501977

Human genetic variation shapes the antibody repertoire across B cell development., PMID:40475565

B cell receptor silencing reveals origin and dependencies of high-grade B cell lymphomas with MYC and BCL2 rearrangements., PMID:40402557

Considerations for use of humanized IgG1/4 Göttingen minipigs in safety assessment of antibody-based therapeutics., PMID:40398719

[Application of next-generation sequencing technology for the investigation of immunoglobulin variable region characteristics and their prognostic significance in patients with chronic lymphocytic leukemia]., PMID:40355356

Diagnosis On-Demand: Field Evaluation of Microfluidic Paper Device for the Detection of Asymptomatic Malaria., PMID:40350582

Comparison of CSF biomarkers in multiple sclerosis patients treated with natalizumab and rituximab., PMID:40345115

Clonal rearrangements of B and T lymphocytes in minor salivary gland biopsies of Sjögren's disease patients with a focus score of ≥1., PMID:40335403

Heterohybridomas producing human immunoglobulin light chains using CD138-selected bone marrow cells., PMID:40330075

[Localized AL amyloidosis]., PMID:40327620

Puriton attenuates the asthma severity in ovalbumin-induced murine model via balancing Th1/Th2 and inhibiting inflammation., PMID:40323927

Preparation and epitope mapping of monoclonal antibodies against African swine fever virus A238L protein., PMID:40311975

Proliferative glomerulonephritis with monoclonal immunoglobulin deposition coexisting with ANCA-associated glomerulonephritis: a case report., PMID:40308572

Paraneoplastic leukocytoclastic vasculitis mimicking ulcus cruris as rare initial manifestation of smoldering myeloma IgG kappa., PMID:40257478

A Case of Multiple Myeloma with Auer Rod-Like Inclusions in Plasma Cells., PMID:40209791

B-ALL with CD34 Negative and Surface Immunoglobulin Light Chain Restricted Expression., PMID:40209787

Identification of two conserved linear antigenic epitopes on the 2C protein of Senecavirus A., PMID:40209476

A two-column process for bispecific antibody purification based on MabSelect VL resin's strong byproduct removal capability., PMID:40200945

[Amyloid light-chain (AL) amyloidosis and follicular lymphoma: a case report]., PMID:40190438

Therapeutic potential of phytocompounds in rheumatoid arthritis: Molecular insights and clinical applications., PMID:40174276

Rapid affinity-based purification of multi-specific antibodies using Kappa Select and Protein L., PMID:40151946

Design of orthogonal constant domain interfaces to aid proper heavy/light chain pairing of bispecific antibodies., PMID:40126074

Kappa-free light chain as a practical alternative to oligoclonal bands in the diagnosis of multiple sclerosis., PMID:40086224

Diagnostic Utility of Kappa Free Light Chain Index in Adults With Inaugural Optic Neuritis., PMID:40085804

Prognostic relevance of immunoglobulin heavy chain rearrangement and immunoglobulin kappa light chain rearrangement in patients with diffuse large B cell lymphoma., PMID:40063611

Biological signatures in the Alzheimer's continuum discriminate between diagnosis-related and -unrelated associations to ATN categories., PMID:40046342

[BCMA/CS1 bispecific CAR-T cell therapy for multiple myeloma complicated with thrombocytopenia: a case report and literature review]., PMID:40032341

A case of IgG-type heavy chain amyloidosis with membranous nephropathy-like changes with long-term survival., PMID:40021557

Single-Chain Variable Fragments: Targeting Snake Venom Phospholipase A2 and Serine Protease., PMID:39998072

[Construction and identification of a sizeable naive human Fab phage display antibody library]., PMID:39965836

[Assessment of serum free light chains in patients with systemic lupus erythematosus]., PMID:39960251

Daratumumab treatment for kidney-involved light chain deposition disease prevents renal function progression: a case report with 3 years of follow-up and review of the literature., PMID:39949751

Oligoclonal bands and kappa free light chains: Competing parameters or complementary biomarkers?, PMID:39947571

A case of renal infiltration by Bence Jones protein kappa-producing lymphoplasmacytic lymphoma., PMID:39946076

Case report of glomerular histiocytosis associated with non-crystalline IgG-kappa paraproteinemia., PMID:39910484

Biomarkers of Intrathecal Synthesis May Be Associated with Cognitive Impairment at MS Diagnosis., PMID:39859538

Role of FOXO3a in LPS-induced inflammatory conditions in human dental pulp cells., PMID:39824385

Protocols for circulating neutrophil depletion in neonatal C57Bl/6 mice., PMID:39821323

Evaluation of an F Protein-Based Recombinant Protein for Immunization Against Respiratory Syncytial Virus., PMID:39791530

[IgAκ monoclonal immunoglobulin deposition disease: a case report]., PMID:39788598

Multiple myeloma-associated non-crystalline proximal tubulopathy and crystalline cast nephropathy: Biochemical and structural features of disease-causing monoclonal kappa light chains., PMID:39781602

Roles of immunoglobulin GM and KM allotypes and Fcγ receptor 2 A genotypes in humoral immunity to a conserved microbial polysaccharide in pulmonary diseases., PMID:39774260

Mice carrying the full-length human immunoglobulin loci produce antigen-specific human antibodies with the lambda light chain., PMID:39758990

50 Years of Antibody Numbering Schemes: A Statistical and Structural Evaluation Reveals Key Differences and Limitations., PMID:39727482

Baicalein tethers CD274/PD-L1 for autophagic degradation to boost antitumor immunity., PMID:39710370

EXPRESSION OF IMMUNOGLOBULIN LIGHT CHAIN GENES IN STEREOTYPED CASES FROM UKRAINIAN COHORT OF CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS., PMID:39704461

Diagnostic approach for multiple sclerosis: optimizing algorithms for intrathecal synthesis of immunoglobulins., PMID:39703160

Distinguishing Daratumumab from Endogenous Monoclonal Proteins in Serum from Multiple Myeloma Patients Using an Automated Mass Spectrometry System., PMID:39699179

The significance of free light-chain ratio in light-chain monoclonal gammopathy of undetermined significance: a flow cytometry sub-study of the iStopMM screening study., PMID:39695077

Light-Chain Myeloma Presented as Osseus Tumors: A Case Report., PMID:39688111

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-Human Kappa Light Chain Antibody (R3F49) [RHD36907]
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