Catalog No.
RHD31004
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000
Target
ATF3, Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P18847
Applications
ELISA, FCM, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3F05
Targeting mesenchymal monocyte-derived macrophages to enhance the sensitivity of glioblastoma to temozolomide by inhibiting TNF/CELSR2/p65/Kla-HDAC1/EPAS1 axis., PMID:40373963
Tumor β-Catenin Expression Associated With Poor Prognosis to Anti-PD-1 Antibody Monotherapy in Non-small Cell Lung Cancer., PMID:39758230
A rat model for acute limb ischemia using microsized gelatin beads., PMID:38490165
Lung transcriptomics of K18-hACE2 mice highlights mechanisms and genes involved in the MVA-S vaccine-mediated immune response and protection against SARS-CoV-2 infection., PMID:37992765
Distinct functions and transcriptional signatures in orally induced regulatory T cell populations., PMID:37954612
CDK4/6i enhances the antitumor effect of PD1 antibody by promoting TLS formation in ovarian cancer., PMID:37809574
Signaling pathways upregulating glutathione‑specific γ‑glutamylcyclotransferase 1 by 3‑(5'‑hydroxymethyl‑2'‑furyl)‑1‑benzylindazole., PMID:37772365
Intracellular Fusobacterium nucleatum infection attenuates antitumor immunity in esophageal squamous cell carcinoma., PMID:37723150
Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26.ZEBOV/MVA-BN-Filo., PMID:37691146
Expression patterns of serum miR-27a-3p and activating transcription factor 3 in children with bronchial asthma and their correlations with airway inflammation., PMID:37385291
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway., PMID:36738354
Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma., PMID:36563676
Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis., PMID:35738798
The Role of ATF3 in Neuronal Differentiation and Development of Neuronal Networks in Opossum Postnatal Cortical Cultures., PMID:35563354
The ATF3-OPG Axis Contributes to Bone Formation by Regulating the Differentiation of Osteoclasts, Osteoblasts, and Adipocytes., PMID:35408860
NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria., PMID:35029280
Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors., PMID:34792764
Induction of IL-6Rα by ATF3 enhances IL-6 mediated sorafenib and regorafenib resistance in hepatocellular carcinoma., PMID:34687791
Characterization of Organ-Specific Regulatory B Cells Using Single-Cell RNA Sequencing., PMID:34594327
Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo., PMID:34386326
The Periodontium Damage Induces Neuronal Cell Death in the Trigeminal Mesencephalic Nucleus and Neurodegeneration in the Trigeminal Motor Nucleus in C57BL/6J Mice., PMID:33731966
Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review., PMID:33615312
Mechanism of Follicular Helper T Cell Differentiation Regulated by Transcription Factors., PMID:32766317
Critical Role of Intestinal Microbiota in ATF3-Mediated Gut Immune Homeostasis., PMID:32571839
Blocking CTGF/CCN2 reverses neural fibrosis and sensorimotor declines in a rat model of overuse-induced median mononeuropathy., PMID:32379362
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis., PMID:32362324
Activating Transcription Factor 3 (ATF3) Protects Retinal Ganglion Cells and Promotes Functional Preservation After Optic Nerve Crush., PMID:32084268
Targeting SGK1 enhances the efficacy of radiotherapy in locally advanced rectal cancer., PMID:32036218
Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress., PMID:31907991
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency., PMID:31263122
Contribution of spinal cord glial cells to L. amazonensis experimental infection-induced pain in BALB/c mice., PMID:31138231
An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle., PMID:30993183
Modulating cAMP responsive element binding protein 1 attenuates functional and behavioural deficits in rat model of neuropathic pain., PMID:30964189
Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome., PMID:30927920
Transcriptional factor ATF3 protects against colitis by regulating follicular helper T cells in Peyer's patches., PMID:30862736
Human Herpesvirus 6A and 6B inhibit in vitro angiogenesis by induction of Human Leukocyte Antigen G., PMID:30523283
Leishmania donovani induced Unfolded Protein Response delays host cell apoptosis in PERK dependent manner., PMID:30036391
ATF2, but not ATF3, participates in the maintenance of nerve injury-induced tactile allodynia and thermal hyperalgesia., PMID:29921170
Immune cell and transcriptomic analysis of the human decidua in term and preterm parturition., PMID:28962035
Activating transcription factor 3 promotes embryo attachment via up-regulation of leukemia inhibitory factor in vitro., PMID:28577574
The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis., PMID:27870968
The efficacy of nerve growth factor antibody in a mouse model of neuropathic cancer pain., PMID:27194075
Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cells., PMID:26917416
TGRL Lipolysis Products Induce Stress Protein ATF3 via the TGF-β Receptor Pathway in Human Aortic Endothelial Cells., PMID:26709509
Role of c-Jun N-terminal kinase in late nerve regeneration monitored by in vivo imaging of thy1-yellow fluorescent protein transgenic mice., PMID:26613205
Upregulation of CCL2 via ATF3/c-Jun interaction mediated the Bortezomib-induced peripheral neuropathy., PMID:26554515
Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia., PMID:26305977
Heroin activates ATF3 and CytC via c-Jun N-terminal kinase pathways to mediate neuronal apoptosis., PMID:25848832
Characterization and changes in neurotrophin receptor p75-Expressing motor neurons in SOD1(G93A) G1H mice [corrected]., PMID:25711805
Phenotypic changes in dorsal root ganglion and spinal cord in the collagen antibody-induced arthritis mouse model., PMID:25631752
For research use only. Not for human or drug use.
