Catalog No.
RHD27902
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:200-1:1000
Target
BP2, IBP-2, IGFBP2, IGF-binding protein 2, Insulin-like growth factor-binding protein 2, IGFBP-2, IBP2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P18065
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3E96
Cytokine profile of cerebrospinal fluid in pediatric patients with metastatic medulloblastoma., PMID:39524698
IGF2BP2 inhibits invasion and migration of clear cell renal cell carcinoma via targeting Netrin-4 in an m6A-dependent manner., PMID:38780170
Dynamic altruistic cooperation within breast tumors., PMID:38093346
IGFBP2 secretion by mammary adipocytes limits breast cancer invasion., PMID:37436978
Differential Effects of Anti-PD-1/PD-L1 Checkpoint Inhibitors on Adhesion Molecules and Cytokine Secretion by THP-1 Monocytes., PMID:37247886
Effects of leptin on the viability of human ovarian cancer cells and changes in cytokine expression levels., PMID:37155466
High baseline tumor burden-associated macrophages promote an immunosuppressive microenvironment and reduce the efficacy of immune checkpoint inhibitors through the IGFBP2-STAT3-PD-L1 pathway., PMID:37031362
DPP3 expression promotes cell proliferation and migration in vitro and tumour growth in vivo, which is associated with poor prognosis of oesophageal carcinoma., PMID:36382663
Results of TRIO-14, a phase II, multicenter, randomized, placebo-controlled trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-ganitumab in newly diagnosed epithelial ovarian cancer., PMID:34642026
COL11A1 activates cancer-associated fibroblasts by modulating TGF-β3 through the NF-κB/IGFBP2 axis in ovarian cancer cells., PMID:34117361
PM2.5 exposure exaggerates the risk of adverse birth outcomes in pregnant women with pre-existing hyperlipidemia: Modulation role of adipokines and lipidome., PMID:33992945
Cytokine Profiling in Chinese SLE Patients: Correlations with Renal Dysfunction., PMID:33134397
Knockdown of DEPDC1B inhibits the development of glioblastoma., PMID:32684847
Identification and validation of differential plasma proteins levels in epithelial ovarian cancer., PMID:32634479
Chip-based serum proteomics approach to reveal the potential protein markers in the sub-acute stroke patients receiving the treatment of Ginkgo Diterpene Lactone Meglumine Injection., PMID:32413576
Data analysis of PD-1 antibody in the treatment of melanoma patients., PMID:32322636
Astrocytic IGFBP2 and CHI3L1 in cerebrospinal fluid drive cortical metastasis of HER2+breast cancer., PMID:32279122
The expression of cytokines in aqueous humor of high myopic patients with cataracts., PMID:32180680
Estrogen Stimulation of Pleiotrophin Enhances Osteoblast Differentiation and Maintains Bone Mass in IGFBP-2 Null Mice., PMID:32168373
IGFBP2 regulates PD-L1 expression by activating the EGFR-STAT3 signaling pathway in malignant melanoma., PMID:32120023
Insulin-like growth factor-binding proteins play a significant role in the molecular response to imatinib in chronic myeloid leukemia patients., PMID:32104232
Prognostic Value of Circulating IGFBP2 and Related Autoantibodies in Children with Metastatic Rhabdomyosarcomas., PMID:32093404
Exploring the Mesenchymal Stem Cell Secretome for Corneal Endothelial Proliferation., PMID:32089707
Effects of colostrum instead of formula feeding for the first 2 days postnatum on whole-body energy metabolism and its endocrine control in neonatal calves., PMID:32089303
Cervicovaginal Fluid Protein Microarray for Detection of Microbial Invasion of the Amniotic Cavity in Preterm Labor., PMID:32046420
Risk factors and molecular characterization of penile cancer: impact on prognosis and potential targets for systemic therapy., PMID:31895076
Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles., PMID:31171813
Comparison in transcriptome and cytokine profiles of mesenchymal stem cells from human umbilical cord and cord blood., PMID:30769140
Protein array profiling of circulating angiogenesis-related factors during bevacizumab containing treatment in metastatic colorectal cancer., PMID:30592740
Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression., PMID:30272281
Quantitative screening of serum protein biomarkers by reverse phase protein arrays., PMID:30220970
Novel method for rapid identification of micropapillary or solid components in early-stage lung adenocarcinoma., PMID:30180981
Cellular prion protein and γ-synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch., PMID:29527422
Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways., PMID:28223541
Higher IGFBP-1 to IGF-1 serum ratio predicts unfavourable survival in patients with nasopharyngeal carcinoma., PMID:28143425
Effects of Feeding Milk Replacer Ad Libitum or in Restricted Amounts for the First Five Weeks of Life on the Growth, Metabolic Adaptation, and Immune Status of Newborn Calves., PMID:28036351
Sequential high-content profiling of the IgG-autoantibody repertoire reveals novel antigens in rheumatoid arthritis., PMID:27729089
Retrospective Proteomic Analysis of Cellular Immune Responses and Protective Correlates of p24 Vaccination in an HIV Elite Controller Using Antibody Arrays., PMID:27600080
Identification of IGFBP2 and IGFBP3 As Compensatory Biomarkers for CA19-9 in Early-Stage Pancreatic Cancer Using a Combination of Antibody-Based and LC-MS/MS-Based Proteomics., PMID:27579675
Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study., PMID:27211902
Improved Survival of HER2+ Breast Cancer Patients Treated with Trastuzumab and Chemotherapy Is Associated with Host Antibody Immunity against the HER2 Intracellular Domain., PMID:27197192
Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies., PMID:27125842
Precision Medicine: Personalized Proteomics for the Diagnosis and Treatment of Idiopathic Inflammatory Disease., PMID:26848019
Axl, Ferritin, Insulin-Like Growth Factor Binding Protein 2, and Tumor Necrosis Factor Receptor Type II as Biomarkers in Systemic Lupus Erythematosus., PMID:26749069
Increased expression of angiogenic and inflammatory proteins in the vitreous of patients with ischemic central retinal vein occlusion., PMID:25978399
Novel anti IGFBP2 single chain variable fragment inhibits glioma cell migration and invasion., PMID:25944386
Biomarker signatures correlate with clinical outcome in refractory metastatic colorectal cancer patients receiving bevacizumab and everolimus., PMID:25695956
Effects of IGFBP-1 and IGFBP-2 and their fragments on migration and IGF-induced proliferation of human dermal fibroblasts., PMID:25468444
Chemotactic and proangiogenic role of calcium sensing receptor is linked to secretion of multiple cytokines and growth factors in breast cancer MDA-MB-231 cells., PMID:25409930
Growth factors and their receptors derived from human amniotic cells in vitro., PMID:25308731
For research use only. Not for human or drug use.
