Catalog No.
RHD10503
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
ATF2, cAMP response element-binding protein CRE-BP1, CREB2, CREBP1, cAMP-responsive element-binding protein 2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, HB16, Cyclic AMP-dependent transcription factor ATF-2, CREB-2, Cyclic AMP-responsive element-binding protein 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P15336
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3D97
Chitinase-3-like Protein 1 Reduces the Stability of Atherosclerotic Plaque via Impairing Macrophagic Efferocytosis., PMID:39813006
Human rhinovirus 16 induces an ICAM-1-PKR-ATF2 axis to modulate macrophage functions., PMID:39324790
Repolarization of Immunosuppressive Macrophages by Targeting SLAMF7-Regulated CCL2 Signaling Sensitizes Hepatocellular Carcinoma to Immunotherapy., PMID:38484085
α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Cav3.2 calcium signaling in astrocytes., PMID:38378800
Exploring dual effects of dinutuximab beta on cell death and proliferation of insulinoma., PMID:37802653
Induction of Antimicrobial Protein S100A15 Expression by Oral Microbial Pathogens Is Toll-like Receptors-Dependent Activation of c-Jun-N-Terminal Kinase (JNK), p38, and NF-κB Pathways., PMID:36982421
Quiescent Ovarian Cancer Cells Secrete Follistatin to Induce Chemotherapy Resistance in Surrounding Cells in Response to Chemotherapy., PMID:36795892
MAPK Cascade Signaling Is Involved in α-MMC Induced Growth Inhibition of Multiple Myeloma MM.1S Cells via G2 Arrest and Mitochondrial-Pathway-Dependent Apoptosis In Vitro., PMID:36678620
Adult Human Vascular Smooth Muscle Cells on 3D Silk Fibroin Nonwovens Release Exosomes Enriched in Angiogenic and Growth-Promoting Factors., PMID:35215609
Effect of resistance training on satellite cells in old mice - a transcriptome study : implications for sarcopenia., PMID:35188421
Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway., PMID:34551004
Myosin 1c: A novel regulator of glucose uptake in brown adipocytes., PMID:33965643
Wnt-11 as a Potential Prognostic Biomarker and Therapeutic Target in Colorectal Cancer., PMID:31261741
Zika virus-like particles (VLPs): Stable cell lines and continuous perfusion processes as a new potential vaccine manufacturing platform., PMID:31164305
miRNA-451a regulates RPE function through promoting mitochondrial function in proliferative diabetic retinopathy., PMID:30576241
ATF2, but not ATF3, participates in the maintenance of nerve injury-induced tactile allodynia and thermal hyperalgesia., PMID:29921170
Dual regulation of HMGB1 by combined JNK1/2-ATF2 axis with miR-200 family in nonalcoholic steatohepatitis in mice., PMID:29298863
Generation of recombinant affinity reagents against a two-phosphosite epitope of ATF2., PMID:29107187
MicroRNA-30b controls endothelial cell capillary morphogenesis through regulation of transforming growth factor beta 2., PMID:28977001
ATF2 partly mediated the expressions of proliferative factors and inhibited pro-inflammatory factors' secretion in arsenite-treated human uroepithelial cells., PMID:30090515
CIP2A overexpression induces autoimmune response and enhances JNK signaling pathway in human lung cancer., PMID:26560124
Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation., PMID:25961580
Interferon regulatory factor 1 and histone H4 acetylation in systemic lupus erythematosus., PMID:25611806
Activating transcription factor 2 in mesenchymal tumors., PMID:24289970
Conductometric monitoring of protein-protein interactions., PMID:24106799
Cetuximab attenuates its cytotoxic and radiosensitizing potential by inducing fibronectin biosynthesis., PMID:23950208
Wnt5a stimulates chemotactic migration and chemokine production in human neutrophils., PMID:23764954
Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice., PMID:23665276
Smad7 foci are present in micronuclei induced by heavy particle radiation., PMID:23643526
Adeno-associated virus vector mediated expression of an oncogenic retroviral envelope protein induces lung adenocarcinomas in immunocompetent mice., PMID:23251519
Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells., PMID:23153039
Molecular mechanism of macrophage activation by red ginseng acidic polysaccharide from Korean red ginseng., PMID:22474399
Localization and Molecular Characterization of human Breast Cancer Initiating Cells from heterogeneous population of Breast Cancer Mesenchymal Stem cells by Immunofluorescence Microscopy., PMID:24693197
The effect of JDP2 and ATF2 on the epithelial-mesenchymal transition of human pancreatic cancer cell lines., PMID:22109562
Crosstalk between TGF-beta and MAPK signaling during corneal wound healing., PMID:21917935
Transcription factor proteomics: identification by a novel gel mobility shift-three-dimensional electrophoresis method coupled with southwestern blot and high-performance liquid chromatography-electrospray-mass spectrometry analysis., PMID:21880322
A direct ELISA assay for quantitative determination of the inhibitory potency of small molecules inhibitors for JNK3., PMID:21316174
Microarray proteomic analysis discriminates tumorigenic mouse ovarian surface epithelial cells of divergent aggressive potential., PMID:20938528
Epstein-Barr virus-encoded EBNA1 enhances RNA polymerase III-dependent EBER expression through induction of EBER-associated cellular transcription factors., PMID:20843307
Protective effect of P188 in the model of acute trauma to human ankle cartilage: the mechanism of action., PMID:20736797
Elevated GM-CSF and IL-1beta levels compromise the ability of p38 MAPK inhibitors to modulate TNFalpha levels in the human monocytic/macrophage U937 cell line., PMID:20617251
Pigment epithelium-derived factor induces interleukin-10 expression in human macrophages by induction of PPAR gamma., PMID:20553736
Assessment of protein expression levels after transient global cerebral ischemia using an antibody microarray analysis., PMID:20458535
Arsenic Trioxide Modulates DNA Synthesis and Apoptosis in Lung Carcinoma Cells., PMID:20454603
Induced ATF-2 represses CDK4 transcription through dimerization with JunD inhibiting intestinal epithelial cell growth after polyamine depletion., PMID:20181929
cAMP/CREB-mediated transcriptional regulation of ectonucleoside triphosphate diphosphohydrolase 1 (CD39) expression., PMID:20178980
KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium., PMID:20032497
Fas-induced apoptosis of renal cell carcinoma is mediated by apoptosis signal-regulating kinase 1 via mitochondrial damage-dependent caspase-8 activation., PMID:19940360
Autoantibody against activating transcription factor-2 in patients with systemic sclerosis., PMID:19917156
Activation of p38 MAPK pathway by hepatitis C virus E2 in cells transiently expressing DC-SIGN., PMID:19851890
For research use only. Not for human or drug use.
