Catalog No.
RHD07703
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
p54, EWSR2, ETS1, Protein C-ets-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P14921
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3D75
Glycerophospholipid metabolism licenses IgE-mediated mast cell degranulation., PMID:40397574
Sequences within and upstream of the mouse Ets1 gene drive high level expression in B cells, but are not sufficient for consistent expression in T cells., PMID:40053568
Neurons enhance blood-brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion., PMID:39475379
Combined inhibition of MET and VEGF enhances therapeutic efficacy of EGFR TKIs in EGFR-mutant non-small cell lung cancer with concomitant aberrant MET activation., PMID:39354638
Sequences within and upstream of the mouse Ets1 gene drive high level expression in B cells, but are not sufficient for consistent expression in T cells., PMID:39149372
miR-200c-3p regulates α4 integrin-mediated T cell adhesion and migration., PMID:38936759
Sustained silencing peanut allergy by xanthopurpurin is associated with suppression of peripheral and bone marrow IgE-producing B cell., PMID:38380329
Ets1 and IL17RA cooperate to regulate autoimmune responses and skin immunity to Staphylococcus aureus., PMID:37691956
Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy., PMID:37337107
An arrayed CRISPR screen of primary B cells reveals the essential elements of the antibody secretion pathway., PMID:36860866
ISG20L1 acts as a co-activator of DAPK1 in the activation of the p53-dependent cell death pathway., PMID:36855954
Novel Molecular Therapies and Genetic Landscape in Selected Rare Diseases with Hematologic Manifestations: A Review of the Literature., PMID:36766791
The transcription factor E2A can bind to and cleave single-stranded immunoglobulin heavy chain locus DNA., PMID:36434987
Ets1 mediates sorafenib resistance by regulating mitochondrial ROS pathway in hepatocellular carcinoma., PMID:35789155
Autoantibodies Targeting AT1- and ETA-Receptors Link Endothelial Proliferation and Coagulation via Ets-1 Transcription Factor., PMID:35008670
Lipocalin 2 expression promotes tumor progression and therapy resistance by inhibiting ferroptosis in colorectal cancer., PMID:34146401
Glycogen synthase kinase-3 beta (GSK3β)-mediated phosphorylation of ETS1 promotes progression of ovarian carcinoma., PMID:34023818
Transcriptomic Profiles of CD47 in Breast Tumors Predict Outcome and Are Associated with Immune Activation., PMID:33917174
ETS1 polymorphism rs73013527 in relation to serum RANKL levels among patients with RA., PMID:33592912
Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma., PMID:33479306
Genetic Basis of Response of Ghanaian Local Chickens to Infection With a Lentogenic Newcastle Disease Virus., PMID:32849779
Bacteroides fragilis alleviates the symptoms of lupus nephritis via regulating CD1d and CD86 expressions in B cells., PMID:32721450
The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy., PMID:32482755
Secreted stromal protein ISLR promotes intestinal regeneration by suppressing epithelial Hippo signaling., PMID:32128839
Ets1 Controls the Development of B Cell Autoimmune Responses in a Cell-Intrinsic Manner., PMID:31356162
Genetic Analyses of Tanzanian Local Chicken Ecotypes Challenged with Newcastle Disease Virus., PMID:31319636
Polymorphisms in MAPK9 (rs4147385) and CSF1R (rs17725712) are associated with the development of inhibitors in patients with haemophilia A in North China., PMID:31149782
Genetics and Genomic Regions Affecting Response to Newcastle Disease Virus Infection under Heat Stress in Layer Chickens., PMID:30669351
Endothelin-1 triggers human peritoneal mesothelial cells' proliferation via ERK1/2-Ets-1 signaling pathway and contributes to endothelial cell angiogenesis., PMID:30485480
German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells., PMID:30450857
Is granulomatosis with polyangiitis in Asia different from the West?, PMID:30338654
Eribulin Does Not Prevent Epithelial-to-Mesenchymal Transition in HT-29 Intestinal Epithelial Cells., PMID:30221148
ETS1 and PAX5 transcription factors recruit AID to Igh DNA., PMID:30089192
The effect of gap junction-mediated transfer of miR-200b on osteogenesis and angiogenesis in a co-culture of MSCs and HUVECs., PMID:29898921
MicroRNA-326 Upregulates B Cell Activity and Autoantibody Production in Lupus Disease of MRL/lpr Mice., PMID:29858063
Association of ETS1 polymorphism with granulomatosis with polyangiitis and proteinase 3-anti-neutrophil cytoplasmic antibody positive vasculitis in a Japanese population., PMID:29167552
Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1., PMID:28439269
Negative Correlation Between miR-326 and Ets-1 in Regulatory T Cells from new-Onset SLE Patients., PMID:26861134
Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer., PMID:26646320
Requirement for Transcription Factor Ets1 in B Cell Tolerance to Self-Antigens., PMID:26355157
Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels., PMID:26209625
RAC1 P29S regulates PD-L1 expression in melanoma., PMID:26176707
Post-transplant molecularly defined Burkitt lymphomas are frequently MYC-negative and characterized by the 11q-gain/loss pattern., PMID:25795716
Hypoxia-inducible factor-3α promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene., PMID:25626335
Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling., PMID:25564654
Inhibitory effects of transcription factor Ikaros on the expression of liver cancer stem cell marker CD133 in hepatocellular carcinoma., PMID:25301737
Interleukin-8 promotes cell migration through integrin αvβ6 upregulation in colorectal cancer., PMID:25150782
The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma., PMID:25145835
A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels., PMID:24929000
Transcription factor Ets1 regulates expression of thioredoxin-interacting protein and inhibits insulin secretion in pancreatic β-cells., PMID:24897113