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Anti-CCNB1 Antibody (R3D63)

Catalog #:   RHD05705 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG
Applications: IHC
Accession: P14635
Overview

Catalog No.

RHD05705

Species reactivity

Human, Mouse, Rat

Host species

Mouse

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:100

Target

CCNB1, G2/mitotic-specific cyclin-B1, CCNB

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P14635

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3D63

Data Image
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma Tissue using Cyclin B1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded Human tonsils using Cyclin B1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
References

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury., PMID:39890773

Pim1 is Critical in T-cell-independent B-cell Response and MAPK Activation in B Cells., PMID:39505064

The effects of enoxaparin treatment in a xenograft mouse model of oral squamous cell carcinoma: A pilot study., PMID:38853514

The dysfunction of CD8+ T cells triggered by endometriotic stromal cells promotes the immune survival of endometriosis., PMID:38544333

Clinical and Molecular Characteristics of Gonadotroph Pituitary Tumors According to the WHO Classification., PMID:38095839

The predictive value of plasma exosomal lncRNAs/mRNAs in NSCLC patients receiving immunotherapy., PMID:36801676

Reactivity Graph Yields Interpretable IgM Repertoire Signatures as Potential Tumor Biomarkers., PMID:36768923

Knockdown of SASS6 reduces growth of MDA‑MB‑231 triple‑negative breast cancer cells through arrest of the cell cycle at the G2/M phase., PMID:33907854

MiR-96-5p Induced by Palmitic Acid Suppresses the Myogenic Differentiation of C2C12 Myoblasts by Targeting FHL1., PMID:33322515

Toll-like receptor 4 (TLR4) deficiency aggravates dextran sulfate sodium (DSS)-induced intestinal injury by down-regulating IL6, CCL2 and CSF3., PMID:32042729

Heme oxygenase-1 attenuates seawater drowning-induced acute lung injury through a reduction in inflammation and oxidative stress., PMID:31254959

Molecular pathology of the luminal class of urothelial tumors., PMID:31232464

Prognostic value of cyclin A2 and B1 expression in lung carcinoids., PMID:31230818

Anticancer activity of 2'-hydroxyflavanone towards lung cancer., PMID:30546837

Embryonic poly(A)-binding protein is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos., PMID:30302808

Impaired liver regeneration is associated with reduced cyclin B1 in natural killer T cell-deficient mice., PMID:28330461

Tumour-Associated Autoantibodies as Diagnostic Biomarkers for Breast Cancer: A Systematic Review and Meta-Analysis., PMID:26991924

Patterns of cyclin A and B1 immunostaining in papillary thyroid carcinoma., PMID:26706989

Effects of a novel Nodal-targeting monoclonal antibody in melanoma., PMID:26460952

The natural compound gambogic acid radiosensitizes nasopharyngeal carcinoma cells under hypoxic conditions., PMID:26357974

RAC1 P29S regulates PD-L1 expression in melanoma., PMID:26176707

The Tumor Antigen Cyclin B1 Hosts Multiple CD4 T Cell Epitopes Differently Recognized by Pre-Existing Naive and Memory Cells in Both Healthy and Cancer Donors., PMID:26136431

DEPDC1 is a novel cell cycle related gene that regulates mitotic progression., PMID:25902835

Detection of autoantibodies to multiple tumor-associated antigens (TAAs) in the immunodiagnosis of breast cancer., PMID:25355596

A multiparametric serum marker panel as a complementary test to mammography for the diagnosis of node-negative early-stage breast cancer and DCIS in young women., PMID:24957886

Preferential autoimmune response in prostate cancer to cyclin B1 in a panel of tumor-associated antigens., PMID:24860838

Higher levels of antibodies to the tumour-associated antigen cyclin B1 in cancer-free individuals than in patients with breast cancer., PMID:24852823

MTHFR promotes heterochromatin maintenance., PMID:24769206

RyR channel-mediated increase of cytosolic free calcium level signals cyclin B1 degradation during abortive spontaneous egg activation in rat., PMID:24696373

Platelet-derived growth factor receptor alpha (PDGFRα) targeting and relevant biomarkers in ovarian carcinoma., PMID:24183729

Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells., PMID:23580446

The effects of DNA double-strand breaks on mouse oocyte meiotic maturation., PMID:23518501

Cdk1 protein-mediated phosphorylation of receptor-associated protein 80 (RAP80) serine 677 modulates DNA damage-induced G2/M checkpoint and cell survival., PMID:23264621

Oncogenic potential of cyclin kinase subunit-2 in cholangiocarcinoma., PMID:23121546

Tripeptidyl peptidase II in human oral squamous cell carcinoma., PMID:22986808

Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts., PMID:22834967

Evaluation of known oncoantibodies, HER2, p53, and cyclin B1, in prediagnostic breast cancer sera., PMID:22715141

Single-cell mass cytometry adapted to measurements of the cell cycle., PMID:22693166

HIV-1 Tat impairs cell cycle control by targeting the Tip60, Plk1 and cyclin B1 ternary complex., PMID:22391203

Hypoxia signature of splice forms of tryptophanyl-tRNA synthetase marks pancreatic cancer cells with distinct metastatic abilities., PMID:21926542

Role of endoplasmic reticulum stress in the amygdaloid kindling model of rats., PMID:21604154

Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1., PMID:21455311

Identification and regulation of c-Myb target genes in MCF-7 cells., PMID:21261996

Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors., PMID:20981424

Evaluation of serum autoantibody levels in the diagnosis of ovarian endometrioma., PMID:20872572

The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia., PMID:20823107

Protein subcellular localization profiling of breast cancer cells by dissociable antibody microarray staining., PMID:20127686

Gene and protein expression markers of response to combined antiangiogenic and epidermal growth factor targeted therapy in renal cell carcinoma., PMID:20089566

Oral administration of caffeine during voluntary exercise markedly decreases tissue fat and stimulates apoptosis and cyclin B1 in UVB-treated skin of hairless p53-knockout mice., PMID:19926639

Immunity against cyclin B1 tumor antigen delays development of spontaneous cyclin B1-positive tumors in p53 (-/-) mice., PMID:19769738

Datasheet

Document Download

Anti-CCNB1 Antibody (R3D63).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-CCNB1 Antibody (R3D63) [RHD05705]
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